Browsing HMS Scholarly Articles by Keyword "validation"
Now showing items 1-4 of 4
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Bioinformatics Workflow for Clinical Whole Genome Sequencing at Partners HealthCare Personalized Medicine
(MDPI, 2016)Effective implementation of precision medicine will be enhanced by a thorough understanding of each patient’s genetic composition to better treat his or her presenting symptoms or mitigate the onset of disease. This ideally ... -
The Illusion of Distribution-Free Small-Sample Classification in Genomics
(Bentham Science Publishers, 2011)Classification has emerged as a major area of investigation in bioinformatics owing to the desire to discriminate phenotypes, in particular, disease conditions, using high-throughput genomic data. While many classification ... -
On evaluating brain tissue classifiers without a ground truth
(Elsevier BV, 2007)In this paper, we present a set of techniques for the evaluation of brain tissue classifiers on a large data set of MR images of the head. Due to the difficulty of establishing a gold standard for this type of data, we ... -
Technical and clinical validation of an environmental exposure unit for ragweed
(Dove Medical Press, 2016)Background: Allergic rhinitis is a common condition, with ragweed pollen one of the more prevalent aeroallergens. Environmental exposure units such as the Allergen BioCube® are valuable models for clinical allergy studies. ...