Browsing SPH Scholarly Articles by Title
Now showing items 1024-1043 of 6362
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Characterization of mycobacterial virulence genes through genetic interaction mapping
(National Academy of Sciences, 2006)We have previously shown that approximate to 5% of the genes encoded by the genome of Mycobacterium tuberculosis are specifically required for the growth or survival of this bacterium during infection. This corresponds to ... -
Characterization of Occupational Exposures to Cleaning Products Used for Common Cleaning Tasks-A Pilot Study of Hospital Cleaners
(BioMed Central, 2009)Background: In recent years, cleaning has been identified as an occupational risk because of an increased incidence of reported respiratory effects, such as asthma and asthma-like symptoms among cleaning workers. Due to ... -
Characterization of Phthalate Exposure among Pregnant Women Assessed by Repeat Air and Urine Samples
(National Institute of Environmental Health Sciences, 2008)Background: Although urinary concentrations of phthalate metabolites are frequently used as biomarkers in epidemiologic studies, variability during pregnancy has not been characterized. Methods: We measured phthalate ... -
Characterization of two distinct early post-entry blocks to HIV-1 in common marmoset lymphocytes
(Nature Publishing Group, 2016)In nature, primate lentiviruses infect humans and several Old World monkeys and apes. However, to date, lentiviruses infecting New World monkeys have not been described. We studied the susceptibility of common marmoset ... -
The Characterization of Upper-Room Ultraviolet Germicidal Irradiation in Inactivating Airborne Microorganisms
(The National Institute of Environmental Health Sciences, 2002)In this study, we explored the efficacy of upper-room ultraviolet germicidal irradiation (UVGI) in reducing the concentration of Serratia marcescens and Mycobacterium bovis bacille Calmette-Guérin (BCG) aerosols in enclosed ... -
Characterization of Vascular Disease Risk in Postmenopausal Women and Its Association with Cognitive Performance
(Public Library of Science, 2013)Objectives: While global measures of cardiovascular (CV) risk are used to guide prevention and treatment decisions, these estimates fail to account for the considerable interindividual variability in pre-clinical risk ... -
Characterizing Associations and SNP-Environment Interactions for GWAS-Identified Prostate Cancer Risk Markers—Results from BPC3
(Public Library of Science, 2011)Genome-wide association studies (GWAS) have identified multiple single nucleotide polymorphisms (SNPs) associated with prostate cancer risk. However, whether these associations can be consistently replicated, vary with ... -
Characterizing redescriptions using persistent homology to isolate genetic pathways contributing to pathogenesis
(BioMed Central, 2016)Background: Complex diseases may have multiple pathways leading to disease. E.g. coronary artery disease evolves from arterial damage to their epithelial layers, but has multiple causal pathways. More challenging, those ... -
Characterizing the Epidemiological Transition in Mexico: National and Subnational Burden of Diseases, Injuries, and Risk Factors
(Public Library of Science, 2008)Background: Rates of diseases and injuries and the effects of their risk factors can have substantial subnational heterogeneity, especially in middle-income countries like Mexico. Subnational analysis of the burden of ... -
Charitable Platforms in Global Surgery: A Systematic Review of their Effectiveness, Cost-Effectiveness, Sustainability, and Role Training
(Springer US, 2014)Objective: This study was designed to propose a classification scheme for platforms of surgical delivery in low- and middle-income countries (LMICs) and to review the literature documenting their effectiveness, cost-effectiveness, ... -
Chemoprevention of cancer: current evidence and future prospects
(F1000Research, 2015)Cancer chemoprevention refers to the use of agents for the inhibition, delay, or reversal of carcinogenesis before invasion. In the present review, agents examined in the context of cancer chemoprevention are classified ... -
Chemoproteomic profiling of host and pathogen enzymes active in cholera
(2016)Activity-based protein profiling (ABPP) is a chemoproteomic tool for detecting active enzymes in complex biological systems. We used ABPP to identify secreted bacterial and host serine hydrolases that are active in animals ... -
Chemotherapy refractory testicular germ cell tumor is associated with a variant in Armadillo Repeat gene deleted in Velco-Cardio-Facial syndrome (ARVCF)
(Frontiers Media S.A., 2012)Introduction: There is evidence that inherited genetic variation affects both testicular germ cell tumor (TGCT) treatment outcome and risks of late-complications arising from cisplatin-based chemotherapy. Using a candidate ... -
Chikungunya Fever, Mauritius, 2006
(Centers for Disease Control and Prevention, 2008) -
Child Mortality Estimation: Accelerated Progress in Reducing Global Child Mortality, 1990–2010
(Public Library of Science, 2012)Monitoring development indicators has become a central interest of international agencies and countries for tracking progress towards the Millennium Development Goals. In this review, which also provides an introduction ... -
Child Mortality Estimation: Methods Used to Adjust for Bias due to AIDS in Estimating Trends in Under-Five Mortality
(Public Library of Science, 2012)In most low- and middle-income countries, child mortality is estimated from data provided by mothers concerning the survival of their children using methods that assume no correlation between the mortality risks of the ... -
A Child with Chronic Manganese Exposure from Drinking Water
(U.S. Department of Health and Human Services & National Institute of Environmental Health Sciences, 2002)The patient's family bought a home in a suburb, but the proximity of the house to wetlands and its distance from the town water main prohibited connecting the house to town water. The family had a well drilled and they ... -
Childcare Attendance and Obesity Risk
(2016)BACKGROUND AND OBJECTIVES: Several observational studies have revealed that children who receive nonparental childcare are at increased risk of obesity. However, this may be due to unmeasured confounding or selection into ...