Browsing SPH Scholarly Articles by Title

Now showing items 1091-1110 of 6362

    • Circulating insulin-like growth factor axis and the risk of pancreatic cancer in four prospective cohorts 

      Wolpin, B. M.; Michaud, D. S.; Giovannucci, E. L.; Schernhammer, E. S.; Stampfer, Meir; Manson, J. E.; Cochrane, B. B.; Rohan, T. E.; Ma, J.; Pollak, M. N.; Fuchs, C. S. (Springer Nature, 2007)
      Insulin-like growth factor (IGF)-I induces growth in pancreatic cancer cells and blockade of the IGF-I receptor has antitumour activity. The association of plasma IGF-I and IGF binding protein-3 (IGFBP-3) with pancreatic ...

    • Circulating Insulin-Like Growth Factor Binding Protein-1 and the Risk of Pancreatic Cancer 

      Wolpin, B. M.; Michaud, D. S.; Giovannucci, E. L.; Schernhammer, E. S.; Stampfer, Meir; Manson, J. E.; Cochrane, B. B.; Rohan, T. E.; Ma, J.; Pollak, M. N.; Fuchs, C. S. (American Association for Cancer Research, 2007)
      Insulin-like growth factor (IGF)-1 has growth-promoting effects on pancreatic cancer cells, and elevated fasting serum insulin has been linked to pancreatic cancer risk. IGF binding protein-1 (IGFBP-1) is a downstream ...

    • Circulating Levels of Resistin and Risk of Type 2 Diabetes in Men and Women: Results from Two Prospective Cohorts 

      Chen, Brian H.; Song, Yiqing; Ding, Eric L.; Roberts, Christian K.; Manson, JoAnn Elisabeth; Rifai, Nader; Buring, Julie Elizabeth; Gaziano, John Michael; Liu, Simin (American Diabetes Association, 2009)
      OBJECTIVE—The purpose of this study was to investigate the role of circulating resistin levels in the development of type 2 diabetes using two prospective cohorts of well-characterized men and women. RESEARCH DESIGN AND ...

    • Circulating levels of vitamin D and colon and rectal cancer: the Physicians’ Health Study and a meta-analysis of prospective studies 

      Lee, Jung Eun; Li, Haojie; Chan, Andrew T.; Hollis, Bruce W.; Lee, I-Min; Stampfer, Meir; Wu, Kana; Giovannucci, Edward; Ma, Jing (American Association for Cancer Research, 2011)
      It remains unknown whether increased risk with low levels of vitamin D is present for colon and/or rectal cancer. To investigate the association between circulating vitamin D levels and colon and rectal cancer, we examined ...

    • Circulating Long-Chain Omega-3 Fatty Acids and Incidence of Congestive Heart Failure in Older Adults: the Cardiovascular Health Study 

      Mozaffarian, Dariush; Lemaitre, Rozenn N.; King, Irena B.; Song, Xiaoling; Spiegelman, Donna; Sacks, Frank M.; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Siscovick, David S. (American College of Physicians, 2011)
      Background: Few previous studies have evaluated associations between long-chain omega-3 fatty acids and incidence of congestive heart failure (CHF), and those that have are typically based on diet questionnaires and yield ...

    • Circulating Metabolites and Survival Among Patients with Pancreatic Cancer 

      Yuan, Chen; Clish, Clary; Wu, Chen; Mayers, Jared; Kraft, Peter; Townsend, Mary; Zhang, Mingfeng; Tworoger, Shelley; Bao, Ying; Qian, Zhi Rong; Rubinson, Douglas; Ng, Kimmie; Giovannucci, Edward; Ogino, Shuji; Stampfer, Meir; Gaziano, John Michael; Ma, Jing; Sesso, Howard; Anderson, Garnet; Cochrane, Barbara; Manson, JoAnn; Torrence, Margaret; Kimmelman, Alec; Amundadottir, Laufey; Vander Heiden, Matthew G.; Fuchs, Charles; Wolpin, Brian (Oxford University Press, 2016)
      Background: Pancreatic tumors cause changes in whole-body metabolism, but whether prediagnostic circulating metabolites predict survival is unknown. Methods: We measured 82 metabolites by liquid chromatography-mass ...

    • Circulating MicroRNAs: Association with Lung Function in Asthma 

      Kho, Alvin T.; Sharma, Sunita; Davis, Joshua S.; Spina, Joseph; Howard, Dagnie; McEnroy, Kevin; Moore, Kip; Sylvia, Jody; Qiu, Weiliang; Weiss, Scott T.; Tantisira, Kelan G. (Public Library of Science, 2016)
      Background: MicroRNAs are key transcriptional and network regulators previously associated with asthma susceptibility. However, their role in relation to asthma severity has not been delineated. Objective: We hypothesized ...

    • Circulating Mitochondrial DNA in Patients in the ICU as a Marker of Mortality: Derivation and Validation 

      Nakahira, Kiichi; Kyung, Sun-Young; Rogers, Angela J.; Gazourian, Lee; Youn, Sojung; Massaro, Anthony F.; Quintana, Carolina; Osorio, Juan C.; Wang, Zhaoxi; Zhao, Yang; Lawler, Laurie A.; Christie, Jason D.; Meyer, Nuala J.; Causland, Finnian R. Mc.; Waikar, Sushrut S.; Waxman, Aaron B.; Chung, Raymond T.; Bueno, Raphael; Rosas, Ivan O.; Fredenburgh, Laura E.; Baron, Rebecca M.; Christiani, David C.; Hunninghake, Gary M.; Choi, Augustine M. K. (Public Library of Science, 2013)
      Background: Mitochondrial DNA (mtDNA) is a critical activator of inflammation and the innate immune system. However, mtDNA level has not been tested for its role as a biomarker in the intensive care unit (ICU). We hypothesized ...

    • Circulating Mucosal Associated Invariant T Cells Are Activated in Vibrio cholerae O1 Infection and Associated with Lipopolysaccharide Antibody Responses 

      Leung, Daniel T.; Bhuiyan, Taufiqur R.; Nishat, Naoshin S.; Hoq, Mohammad Rubel; Aktar, Amena; Rahman, M. Arifur; Uddin, Taher; Khan, Ashraful I.; Chowdhury, Fahima; Charles, Richelle C.; Harris, Jason B.; Calderwood, Stephen B.; Qadri, Firdausi; Ryan, Edward T. (Public Library of Science, 2014)
      Background: Mucosal Associated Invariant T (MAIT) cells are innate-like T cells found in abundance in the intestinal mucosa, and are thought to play a role in bridging the innate-adaptive interface. Methods: We measured ...

    • Circulating N‐Linked Glycoprotein Side‐Chain Biomarker, Rosuvastatin Therapy, and Incident Cardiovascular Disease: An Analysis From the JUPITER Trial 

      Akinkuolie, Akintunde O.; Glynn, Robert J.; Padmanabhan, Latha; Ridker, Paul M; Mora, Samia (John Wiley and Sons Inc., 2016)
      Background: GlycA, a novel protein glycan biomarker of N‐acetyl side chains of acute‐phase proteins, was recently associated with incident cardiovascular disease (CVD) in healthy women. Whether GlycA predicts CVD events ...

    • Circulating Omega‐3 Polyunsaturated Fatty Acids and Subclinical Brain Abnormalities on MRI in Older Adults: The Cardiovascular Health Study 

      Virtanen, Jyrki K.; Siscovick, David S.; Lemaitre, Rozenn N.; Longstreth, William T.; Spiegelman, Donna; Rimm, Eric B.; King, Irena B.; Mozaffarian, Dariush (Blackwell Publishing Ltd, 2013)
      Background: Consumption of tuna or other broiled or baked fish, but not fried fish, is associated with fewer subclinical brain abnormalities on magnetic resonance imaging (MRI). We investigated the association between ...

    • Circulating Persistent Organic Pollutants and Body Fat Distribution, Evidence from NHANES 1999-2004 

      Zong, Geng; Grandjean, Philippe; Wu, Hongyu; Sun, Qi (2015)
      Objective: To evaluate and compare the correlations of various circulating persistent organic pollutants (POPs) with fat mass percentages (FM%) of trunk, leg, and whole body measured by Dual-energy X-ray absorptiometry. ...

    • Circulating Pre-Diagnostic Interleukin-6 and C-Reactive Protein and Prostate Cancer Incidence and Mortality 

      Stark, Jennifer Rider; Li, Haojie; Kraft, Peter; Kurth, Tobias; Giovannucci, Edward L.; Stampfer, Meir; Ma, Jing; Mucci, Lorelei A. (Wiley, 2009)
      Interleukin-6 (IL-6) and C-reactive protein (CRP) are elevated in prostate cancer patients, but the role of prediagnostic levels of these inflammatory mediators on prostate cancer outcomes is unclear. We undertook a large, ...

    • Circulating prolactin and in situ breast cancer risk in the European EPIC cohort: a case-control study 

      Tikk, Kaja; Sookthai, Disorn; Fortner, Renée T; Johnson, Theron; Rinaldi, Sabina; Romieu, Isabelle; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Clavel-Chapelon, Françoise; Baglietto, Laura; Boeing, Heiner; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Masala, Giovanna; Krogh, Vittorio; Tumino, Rosario; Ricceri, Fulvio; Mattiello, Amalia; Agudo, Antonio; Menéndez, Virginia; Sánchez, María-José; Amiano, Pilar; Chirlaque, Maria-Dolores; Barricarte, Aurelio; Bueno-de-Mesquita, HBas; Monninkhof, Evelyn M; Onland-Moret, N Charlotte; Andresson, Anne; Sund, Malin; Weiderpass, Elisabete; Khaw, Kay-Tee; Key, Timothy J; Travis, Ruth C; Merritt, Melissa A; Riboli, Elio; Dossus, Laure; Kaaks, Rudolf (BioMed Central, 2015)
      Introduction: The relationship between circulating prolactin and invasive breast cancer has been investigated previously, but the association between prolactin levels and in situ breast cancer risk has received less ...

    • Circulating Very-Long Chain Saturated Fatty Acids and Incident Coronary Heart Disease in U.S. Men and Women 

      Malik, Vasanti; Chiuve, Stephanie; Campos, Hannia; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Mozaffarian, Dariush; Hu, Frank; Sun, Qi (American Heart Association, 2015)
      Background-Circulating very-long-chain saturated fatty acids (VLCSFAs) may play an active role in the origin of cardiometabolic diseases.Methods and Results-We measured 3 VLCSFAs (C20:0, C22:0, and C24:0) in plasma and ...

    • Circulating vitamin D in relation to cancer incidence and survival of the head and neck and oesophagus in the EPIC cohort 

      Fanidi, Anouar; Muller, David C.; Midttun, Øivind; Ueland, Per Magne; Vollset, Stein Emil; Relton, Caroline; Vineis, Paolo; Weiderpass, Elisabete; Skeie, Guri; Brustad, Magritt; Palli, Domenico; Tumino, Rosario; Grioni, Sara; Sacerdote, Carlotta; Bueno-de-Mesquita, H. B(as).; Peeters, Petra H.; Boutron-Ruault, Marie-Christine; Kvaskoff, Marina; Cadeau, Claire; Huerta, José María; Sánchez, Maria-José; Agudo, Antonio; Lasheras, Cristina; Quirós, J. Ramón; Chamosa, Saioa; Riboli, Elio; Travis, Ruth C.; Ward, Heather; Murphy, Neil; Khaw, Kay-Tee; Trichopoulou, Antonia; Lagiou, Pagona; Papatesta, Eleni-Maria; Boeing, Heiner; Kuehn, Tilman; Katzke, Verena; Steffen, Annika; Johansson, Anders; Brennan, Paul; Johansson, Mattias (Nature Publishing Group, 2016)
      Experimental and epidemiological data suggest that vitamin D play a role in pathogenesis and progression of cancer, but prospective data on head and neck cancer (HNC) and oesophagus cancer are limited. The European Prospective ...

    • CIS Sequence Effects on Gene Expression 

      Bergen, Andrew W; McDaniel, Timothy K; Kuhn, Kenneth; Pfeiffer, Ruth; Kakol, Jerry; Bender, Patrick; Jacobs, Kevin; Packer, Bernice; Chanock, Stephen J; Yeager, Meredith; Baccarelli, Andrea (BioMed Central, 2007)
      Background: Sequence and transcriptional variability within and between individuals are typically studied independently. The joint analysis of sequence and gene expression variation (genetical genomics) provides insight ...

    • Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer 

      Lawrenson, Kate; Li, Qiyuan; Kar, Siddhartha; Seo, Ji-Heui; Tyrer, Jonathan; Spindler, Tassja J.; Lee, Janet; Chen, Yibu; Karst, Alison; Drapkin, Ronny; Aben, Katja K. H.; Anton-Culver, Hoda; Antonenkova, Natalia; Bowtell, David; Webb, Penelope M.; deFazio, Anna; Baker, Helen; Bandera, Elisa V.; Bean, Yukie; Beckmann, Matthias W.; Berchuck, Andrew; Bisogna, Maria; Bjorge, Line; Bogdanova, Natalia; Brinton, Louise A.; Brooks-Wilson, Angela; Bruinsma, Fiona; Butzow, Ralf; Campbell, Ian G.; Carty, Karen; Chang-Claude, Jenny; Chenevix-Trench, Georgia; Chen, Anne; Chen, Zhihua; Cook, Linda S.; Cramer, Daniel W.; Cunningham, Julie M.; Cybulski, Cezary; Dansonka-Mieszkowska, Agnieszka; Dennis, Joe; Dicks, Ed; Doherty, Jennifer A.; Dörk, Thilo; du Bois, Andreas; Dürst, Matthias; Eccles, Diana; Easton, Douglas T.; Edwards, Robert P.; Eilber, Ursula; Ekici, Arif B.; Fasching, Peter A.; Fridley, Brooke L.; Gao, Yu-Tang; Gentry-Maharaj, Aleksandra; Giles, Graham G.; Glasspool, Rosalind; Goode, Ellen L.; Goodman, Marc T.; Grownwald, Jacek; Harrington, Patricia; Harter, Philipp; Hasmad, Hanis Nazihah; Hein, Alexander; Heitz, Florian; Hildebrandt, Michelle A. T.; Hillemanns, Peter; Hogdall, Estrid; Hogdall, Claus; Hosono, Satoyo; Iversen, Edwin S.; Jakubowska, Anna; James, Paul; Jensen, Allan; Ji, Bu-Tian; Karlan, Beth Y.; Kruger Kjaer, Susanne; Kelemen, Linda E.; Kellar, Melissa; Kelley, Joseph L.; Kiemeney, Lambertus A.; Krakstad, Camilla; Kupryjanczyk, Jolanta; Lambrechts, Diether; Lambrechts, Sandrina; Le, Nhu D.; Lee, Alice W.; Lele, Shashi; Leminen, Arto; Lester, Jenny; Levine, Douglas A.; Liang, Dong; Lissowska, Jolanta; Lu, Karen; Lubinski, Jan; Lundvall, Lene; Massuger, Leon F. A. G.; Matsuo, Keitaro; McGuire, Valerie; McLaughlin, John R.; Nevanlinna, Heli; McNeish, Ian; Menon, Usha; Modugno, Francesmary; Moysich, Kirsten B.; Narod, Steven A.; Nedergaard, Lotte; Ness, Roberta B.; Azmi, Mat Adenan Noor; Odunsi, Kunle; Olson, Sara H.; Orlow, Irene; Orsulic, Sandra; Weber, Rachel Palmieri; Pearce, Celeste L.; Pejovic, Tanja; Pelttari, Liisa M.; Permuth-Wey, Jennifer; Phelan, Catherine M.; Pike, Malcolm C.; Poole, Elizabeth M.; Ramus, Susan J.; Risch, Harvey A.; Rosen, Barry; Rossing, Mary Anne; Rothstein, Joseph H.; Rudolph, Anja; Runnebaum, Ingo B.; Rzepecka, Iwona K.; Salvesen, Helga B.; Schildkraut, Joellen M.; Schwaab, Ira; Sellers, Thomas A.; Shu, Xiao-Ou; Shvetsov, Yurii B.; Siddiqui, Nadeem; Sieh, Weiva; Song, Honglin; Southey, Melissa C.; Sucheston, Lara; Tangen, Ingvild L.; Teo, Soo-Hwang; Terry, Kathryn L.; Thompson, Pamela J.; Timorek, Agnieszka; Tsai, Ya-Yu; Tworoger, Shelley S.; van Altena, Anne M.; Van Nieuwenhuysen, Els; Vergote, Ignace; Vierkant, Robert A.; Wang-Gohrke, Shan; Walsh, Christine; Wentzensen, Nicolas; Whittemore, Alice S.; Wicklund, Kristine G.; Wilkens, Lynne R.; Woo, Yin-Ling; Wu, Xifeng; Wu, Anna H.; Yang, Hannah; Zheng, Wei; Ziogas, Argyrios; Monteiro, Alvaro; Pharoah, Paul D.; Gayther, Simon A.; Freedman, Matthew L. (Nature Pub. Group, 2015)
      Genome-wide association studies have reported 11 regions conferring risk of high-grade serous epithelial ovarian cancer (HGSOC). Expression quantitative trait locus (eQTL) analyses can identify candidate susceptibility ...

    • Cistrome Data Browser: a data portal for ChIP-Seq and chromatin accessibility data in human and mouse 

      Mei, Shenglin; Qin, Qian; Wu, Qiu; Sun, Hanfei; Zheng, Rongbin; Zang, Chongzhi; Zhu, Muyuan; Wu, Jiaxin; Shi, Xiaohui; Taing, Len; Liu, Tao; Brown, Myles; Meyer, Clifford A.; Liu, X. Shirley (Oxford University Press, 2017)
      Chromatin immunoprecipitation, DNase I hypersensitivity and transposase-accessibility assays combined with high-throughput sequencing enable the genome-wide study of chromatin dynamics, transcription factor binding and ...

    • Citrus Consumption and Risk of Cutaneous Malignant Melanoma 

      Wu, Shaowei; Han, Jiali; Feskanich, Diane; Cho, Eunyoung; Stampfer, Meir; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Qureshi, Abrar (American Society of Clinical Oncology, 2015)
      Purpose: Citrus products are widely consumed foods that are rich in psoralens and furocoumarins, a group of naturally occurring chemicals with potential photocarcinogenic properties. We prospectively evaluated the risk of ...