Now showing items 1141-1160 of 6362

    • Co-Operative Additive Effects between HLA Alleles in Control of HIV-1 

      Matthews, Philippa C.; Listgarten, Jennifer; Carlson, Jonathan M.; Payne, Rebecca; Huang, Kuan-Hsiang Gary; Frater, John; Goedhals, Dominique; Steyn, Dewald; van Vuuren, Cloete; Paioni, Paolo; Jooste, Pieter; Ogwu, Anthony; Shapiro, Roger L.; Mncube, Zenele; Ndung'u, Thumbi; Walker, Bruce David; Heckerman, David; Goulder, Philip J. R. (Public Library of Science, 2012)
      Background: HLA class I genotype is a major determinant of the outcome of HIV infection, and the impact of certain alleles on HIV disease outcome is well studied. Recent studies have demonstrated that certain HLA class I ...
    • Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins 

      Richard, Jonathan; Pacheco, Beatriz; Gohain, Neelakshi; Veillette, Maxime; Ding, Shilei; Alsahafi, Nirmin; Tolbert, William D.; Prévost, Jérémie; Chapleau, Jean-Philippe; Coutu, Mathieu; Jia, Manxue; Brassard, Nathalie; Park, Jongwoo; Courter, Joel R.; Melillo, Bruno; Martin, Loïc; Tremblay, Cécile; Hahn, Beatrice H.; Kaufmann, Daniel E.; Wu, Xueling; Smith, Amos B.; Sodroski, Joseph; Pazgier, Marzena; Finzi, Andrés (Elsevier, 2016)
      Human immunodeficiency virus type 1 (HIV-1) has evolved a sophisticated strategy to conceal conserved epitopes of its envelope glycoproteins (Env) recognized by antibody-dependent cellular cytotoxicity (ADCC)-mediating ...
    • Codynamics of Four Variables Involved in Dengue Transmission and Its Control by Community Intervention: A System of Four Difference Equations 

      Awerbuch, Tamara Eugenia; Levins, Richard; Predescu, M. (Hindawi Publishing Corporation, 2014)
      In the case of Dengue transmission and control, the interaction of nature and society is captured by a system of difference equations. For the purpose of studying the dynamics of these interactions, four variables involved ...
    • Coffee Consumption and Incidence of Colorectal Cancer in Two Prospective Cohort Studies of Swedish Women and Men 

      Larsson, Susanna C.; Bergkvist, Leif; Giovannucci, Edward; Wolk, Alicja (Oxford University Press, 2006)
      Investigators have reported an inverse association between coffee consumption and risk of colorectal cancer in several case-control studies, but prospective studies, most of them involving small numbers of cases, have not ...
    • Coffee Consumption and Prostate Cancer Risk and Progression in the Health Professionals Follow-up Study 

      Wilson, Kathryn M.; Kasperzyk, Julie L.; Rider, Jennifer R.; Kenfield, Stacey; Dam, Rob van; Stampfer, Meir; Giovannucci, Edward; Mucci, Lorelei A. (Oxford University Press, 2011)
      Background Coffee contains many biologically active compounds, including caffeine and phenolic acids, that have potent antioxidant activity and can affect glucose metabolism and sex hormone levels. Because of these biological ...
    • Coffee Consumption and Risk for Type 2 Diabetes Mellitus 

      Salazar-Martinez, Eduardo; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Ascherio, Alberto; Manson, JoAnn E.; Leitzmann, Michael F.; Stampfer, Meir; Hu, Frank B. (American College of Physicians, 2004)
    • Coffee Consumption and Risk of Cardiovascular Diseases and All-Cause Mortality Among Men With Type 2 Diabetes 

      Zhang, Weili; Lopez-Garcia, Esther; Li, Tricia Y.; Hu, Frank B.; van Dam, Rob M. (American Diabetes Association, 2009)
      OBJECTIVE: Coffee consumption has been linked to detrimental acute metabolic and hemodynamic effects. We investigated coffee consumption in relation to risk of CVDs and mortality in diabetic men. RESEARCH DESIGN AND METHODS: ...
    • Coffee Consumption and Risk of Myocardial Infarction among Older Swedish Women 

      Rosner, Sarah; Åkesson, Agneta; Stampfer, Meir; Wolk, Alicja (Oxford University Press, 2007)
      Numerous studies have examined the association between coffee consumption and risk of myocardial infarction (MI), but results have been inconsistent. Case-control studies generally suggest a harmful effect of coffee drinking, ...
    • Coffee consumption and the risk of overall and fatal prostate cancer in the NIH-AARP Diet and Health study 

      Bosire, Claire; Stampfer, Meir; Subar, Amy F.; Wilson, Kathryn M.; Park, Yikyung; Sinha, Rashmi (Springer (part of Springer Nature), 2013)
      Evidence on the association between coffee consumption and prostate cancer risk is inconsistent; furthermore, few studies have examined the relationship between coffee consumption and fatal prostate cancer. The aim of this ...
    • Coffee consumption and total mortality: a meta-analysis of twenty prospective cohort studies 

      Je, Youjin; Giovannucci, Edward (Cambridge University Press, 2014)
      Coffee consumption has been shown to be associated with various health outcomes, but no comprehensive review and meta-analysis of the association between coffee consumption and total mortality has been conducted. To ...
    • Coffee intake is associated with lower risk of symptomatic gallstone disease in women 

      Leitzmann, Michael F.; Stampfer, Meir; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Spiegelman, Donna; Colditz, Graham A.; Giovannucci, Edward L. (Elsevier, 2002)
      Background: & Aims: Metabolic studies have shown that coffee affects several hepatobiliary processes that are involved in cholesterol lithogenesis. We previously showed that coffee drinking was associated with a lower ...
    • Coffee, Tea and Sugar-sweetened Carbonated Soft Drink Intake and Pancreatic Cancer Risk: A Pooled Analysis of 14 Cohort Studies 

      Genkinger, Jeanine; Li, Ruifeng; Spiegelman, Donna; Anderson, Kristin; Albanes, Demetrius; Bergkvist, Leif; Bernstein, Leslie; Black, Amanda; van den Brandt, Piet A.; English, Dallas; Freudenheim, Jo; Fuchs, Charles; Giles, Graham; Giovannucci, Edward; Goldbohm, R. Alexandra; Horn-Ross, Pamela; Jacobs, Eric; Koushik, Anita; Männistö, Satu; Marshall, James; Miller, Anthony; Patel, Alpa; Robien, Kim; Schairer, Catherine; Stolzenberg-Solomon, Rachael; Wolk, Alicja; Ziegler, Regina; Smith-Warner, Stephanie (American Association for Cancer Research, 2012)
      Background: Coffee has been hypothesized to have pro- and anticarcinogenic properties, whereas tea may contain anticarcinogenic compounds. Studies assessing coffee intake and pancreatic cancer risk have yielded mixed ...
    • Coffee, Tea, and Caffeine Consumption and Incidence of Colon and Rectal Cancer 

      Michels, Karin B.; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Fuchs, Charles S.; Giovannucci, Edward (Oxford University Press, 2005)
      Background. Frequent coffee consumption has been associated with a reduced risk of colorectal cancer in a number of case-control studies. Cohort studies have not revealed such an association but were limited in size. We ...
    • Cognitive deficits and magnetic resonance spectroscopy in adult monozygotic twins with lead poisoning. 

      Weisskopf, Marc G.; Hu, Howard; Mulkern, Robert Vincent; White, Roberta F; Aro, Antonio; Oliveira, Steven; Wright, Robert O. (2004)
      Seventy-one-year-old identical twin brothers with chronic lead poisoning were identified from an occupational medicine clinic roster. Both were retired painters, but one brother (J.G.) primarily removed paint and had a ...
    • Cognitive deficits at age 22 years associated with prenatal exposure to methylmercury 

      Debes, Frodi; Weihe, Pal; Grandjean, Philippe (Elsevier BV, 2016)
      Prenatal exposure to mercury has been associated with adverse effects on child neurodevelopment. The present study aims to determine the extent to which methylmercury-associated cognitive deficits persist into adult age. ...
    • The cohesin-associated protein Wapal is required for proper Polycomb-mediated gene silencing 

      Stelloh, Cary; Reimer, Michael H.; Pulakanti, Kirthi; Blinka, Steven; Peterson, Jonathan; Pinello, Luca; Jia, Shuang; Roumiantsev, Sergei; Hessner, Martin J.; Milanovich, Samuel; Yuan, Guo-Cheng; Rao, Sridhar (BioMed Central, 2016)
      Background: The cohesin complex consists of multiple core subunits that play critical roles in mitosis and transcriptional regulation. The cohesin-associated protein Wapal plays a central role in off-loading cohesin to ...
    • Cohort Profile: The AGES 2003 Cohort Study in Aichi, Japan 

      Nishi, Akihiro; Kondo, Katsunori; Hirai, Hiroshi; Kawachi, Ichiro (Japan Epidemiological Association, 2011)
      Background: The longevity of Japanese is thought to be associated with psychosocial factors such as sense of coherence, social support, and social capital. However, the actual factors responsible and the extent of their ...
    • Cohort Profile: The Resilience for Eating and Activity Despite Inequality (READI) study 

      Ball, Kylie; Cleland, Verity; Salmon, Jo; Timperio, Anna F.; McNaughton, Sarah; Thornton, Lukar; Campbell, Karen; Jackson, Michelle; Baur, Louise A.; Mishra, Gita; Brug, Johannes; Jeffery, Robert W.; King, Abby; Kawachi, Ichiro; Crawford, David A. (Oxford University Press, 2013)
      The Resilience for Eating and Activity Despite Inequality (READI) cohort was established to address the following two key aims: to investigate the pathways (personal, social and structural) by which socio-economic disadvantage ...
    • Collection of Aerosolized Human Cytokines Using Teflon® Filters 

      McKenzie, Jennifer Helen; McDevitt, James J; Fabian, Maria Patricia; Hwang, Grace M.; Milton, Donald Kirby (Public Library of Science, 2012)
      Background: Collection of exhaled breath samples for the analysis of inflammatory biomarkers is an important area of research aimed at improving our ability to diagnose, treat and understand the mechanisms of chronic ...