Browsing SPH Scholarly Articles by Title
Now showing items 1302-1321 of 6362
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A Conceptual Framework to Measure Systems’ Performance during Emergency Preparedness Exercises
(MDPI, 2014)Large-scale public health emergencies require a sophisticated, coordinated response involving multiple entities to protect health and minimize suffering. However, the rarity of such emergencies presents a barrier to gathering ... -
Concerning RNA-guided gene drives for the alteration of wild populations
(eLife Sciences Publications, Ltd, 2014)Gene drives may be capable of addressing ecological problems by altering entire populations of wild organisms, but their use has remained largely theoretical due to technical constraints. Here we consider the potential for ... -
Concerns about SARS-CoV-2 evolution should not hold back efforts to expand vaccination
(2021)When vaccines are in limited supply, expanding the number of people who receive some vaccine can reduce disease and mortality compared to concentrating vaccines in a subset of the population. A corollary of such dose-sparing ... -
Concomitant Socioeconomic, Behavioral, and Biological Factors Associated with the Disproportionate HIV Infection Burden among Black Men Who Have Sex with Men in 6 U.S. Cities
(Public Library of Science, 2014)Background: American Black men who have sex with men (MSM) are disproportionately affected by HIV, but the factors associated with this concentrated epidemic are not fully understood. Methods: Black MSM were enrolled in 6 ... -
Concomitant Use of Single Antiplatelet Therapy With Edoxaban or Warfarin in Patients With Atrial Fibrillation: Analysis From the ENGAGE AF‐TIMI48 Trial
(John Wiley and Sons Inc., 2016)Background: We studied the concomitant use of single antiplatelet therapy (SAPT) on the efficacy and safety of the anti‐Xa agent edoxaban in patients with atrial fibrillation (AF). Methods and Results: ENGAGE AF‐TIMI 48 ... -
Concordance Between Life Satisfaction and Six Elements of Well-Being Among Respondents to a Health Assessment Survey, HealthPartners Employees, Minnesota, 2011
(Centers for Disease Control and Prevention, 2016)Introduction: We assessed and tracked perceptions of well-being among employees of member companies of HealthPartners, a nonprofit health care provider and health insurance company in Bloomington, Minnesota. The objective ... -
Concordance between self-reported pre-pregnancy body mass index (BMI) and BMI measured at the first prenatal study contact
(BioMed Central, 2016)Background: The 2009 Institute of Medicine (IOM) gestational weight recommendations are tailored to women’s pre-pregnancy body mass index (BMI). Limited evidence exists on methods for estimating women’s pre-pregnancy BMI, ... -
Concordance of gene expression in human protein complexes reveals tissue specificity and pathology
(Oxford University Press, 2013)Disease-causing variants in human genes usually lead to phenotypes specific to only a few tissues. Here, we present a method for predicting tissue specificity based on quantitative deregulation of protein complexes. The ... -
Conditioned to eat while watching television? Low-income caregivers’ perspectives on the role of snacking and television viewing among pre-schoolers
(2016)Objective: Although television (TV) viewing is frequently paired with snacking among young children, little is known about the environment in which caregivers promote this behaviour. We describe low-income pre-schoolers' ... -
Confidence Intervals for Heterogeneity Measures in Meta-analysis
(Oxford University Press, 2013)Two methods of quantifying heterogeneity between studies in meta-analysis were studied. One method quantified the proportion of the total variance of the effect estimate due to variation between studies (R-I), and the other ... -
Confirmation of emergence of mutations associated with atovaquone-proguanil resistance in unexposed Plasmodium falciparum isolates from Africa
(BioMed Central, 2006)Background: In vitro and in vivo resistance of Plasmodium falciparum to atovaquone or atovaquone-proguanil hydrochloride combination has been associated to two point mutations in the parasite cytochrome b (cytb) gene ... -
Confounding by indication affects antimicrobial risk factors for methicillin-resistant Staphylococcus aureus but not vancomycin-resistant enterococci acquisition
(BioMed Central, 2014)Background: Observational studies rarely account for confounding by indication, whereby empiric antibiotics initiated for signs and symptoms of infection prior to the diagnosis of infection are then viewed as risk factors ... -
Confounding Effects in "A Six-Gene Signature Predicting Breast Cancer Lung Metastasis"
(American Association for Cancer Research (AACR), 2009)The majority of breast cancer deaths result from metastases rather than from direct effects of the primary tumor itself. Recently, Landemaine and colleagues described a six-gene signature purported to predict lung metastasis ... -
Connectedness, social support and internalising emotional and behavioural problems in adolescents displaced by the Chechen conflict
(Wiley-Blackwell, 2012)The study investigated factors associated with internalising emotional and behavioural problems among adolescents displaced during the most recent Chechen conflict. A cross-sectional survey (N=183) examined relationships ... -
Connexin43 Inhibition Prevents Human Vein Grafts Intimal Hyperplasia
(Public Library of Science, 2015)Venous bypass grafts often fail following arterial implantation due to excessive smooth muscle cells (VSMC) proliferation and consequent intimal hyperplasia (IH). Intercellular communication mediated by Connexins (Cx) ... -
Conscientiousness is modified by genetic variation in catechol-O-methyltransferase to reduce symptom complaints in IBS patients
(BlackWell Publishing Ltd, 2014)Background: Attention to and perception of physical sensations and somatic states can significantly influence reporting of complaints and symptoms in the context of clinical care and randomized trials. Although anxiety and ... -
Consensus Statement on Electronic Health Predictive Analytics: A Guiding Framework to Address Challenges
(AcademyHealth, 2016)Context: The recent explosion in available electronic health record (EHR) data is motivating a rapid expansion of electronic health care predictive analytic (e-HPA) applications, defined as the use of electronic algorithms ... -
Consensus Statement: Atlantic Coast Contaminants Workshop 2000
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Consequences of exposure measurement error for confounder identification in environmental epidemiology
(Wiley-Blackwell, 2003)Non-differential measurement error in the exposure variable is known to attenuate the dose–response relationship. The amount of attenuation introduced in a given situation is not only a function of the precision of the ...