Now showing items 1401-1420 of 6362

    • Cost–effectiveness of CYP2B6 genotyping to optimize efavirenz dosing in HIV clinical practice 

      Schackman, Bruce R; Haas, David W; Park, Sanghee S; Li, X Cynthia; Freedberg, Kenneth A (2016)
      Aims To assess the cost–effectiveness of CYP2B6 genotyping to guide efavirenz dosing for initial HIV therapy in the USA. Methods: We used the Cost–Effectiveness of Preventing AIDS Complications (CEPAC) microsimulation model ...
    • Cotrimoxazole Prophylaxis and Risk of Severe Anemia or Severe Neutropenia in HAART-Exposed, HIV-Uninfected Infants 

      Dryden-Peterson, Scott; Jayeoba, Oluwemimo; Hughes, Michael D.; Jibril, Haruna; McIntosh, Kenneth; Modise, Taolo A.; Asmelash, Aida; Powis, Kathleen M.; Essex, Max; Shapiro, Roger L.; Lockman, Shahin (Public Library of Science, 2013)
      Background: Prophylactic cotrimoxazole is recommended for infants born to HIV-infected mothers. However, cotrimoxazole may increase the risk of severe anemia or neutropenia. Methods: We compared the proportion of HIV-exposed ...
    • Countdown to 2015 country case studies: what can analysis of national health financing contribute to understanding MDG 4 and 5 progress? 

      Mann, Carlyn; Ng, Courtney; Akseer, Nadia; Bhutta, Zulfiqar A; Borghi, Josephine; Colbourn, Tim; Hernández-Peña, Patricia; Huicho, Luis; Malik, Muhammad Ashar; Martinez-Alvarez, Melisa; Munthali, Spy; Salehi, Ahmad Shah; Tadesse, Mekonnen; Yassin, Mohammed; Berman, Peter; Rannan-Eliya, Ravi; Brearley, Lara; Friedman, Howard; Ravishankar, Nirmala; Cortes, Rafael; Mtei, Gemini (BioMed Central, 2016)
      Background: Countdown to 2015 (Countdown) supported countries to produce case studies that examine how and why progress was made toward the Millennium Development Goals (MDGs) 4 and 5. Analysing how health-financing data ...
    • Countdown to 2015 country case studies: what have we learned about processes and progress towards MDGs 4 and 5? 

      Moucheraud, Corrina; Owen, Helen; Singh, Neha S.; Ng, Courtney Kuonin; Requejo, Jennifer; Lawn, Joy E.; Berman, Peter; Salehi, Ahmed; Hong, Zhou; Ronsmans, Carine; Yanqiu, Gao; Kebede, Hillena; Mann, Carlyn; Ruducha, Jenny; Tadesse, Mekonnen; Ngugi, Anthony; Keats, Emily; Macharia, William; Ravishankar, Nirmala; Singh, Neha; Tole, John; Bryce, Jennifer; Colbourn, Tim; Daelmans, Bernadette; Kanyuka, Mercy; Nsona, Humphreys; Askeer, Nadia; Bhutta, Zulfiqar; Bhatti, Zaid; Rizvi, Arjumand; de Guzman, Jessica Niño; Huicho, Luis; Victora, Cesar; Afnan-Holmes, Hoviyeh; John, Theopista; Lawn, Joy; Magoma, Moke; Msemo, Georgina (BioMed Central, 2016)
      Background: Countdown to 2015 was a multi-institution consortium tracking progress towards Millennium Development Goals (MDGs) 4 and 5. Case studies to explore factors contributing to progress (or lack of progress) in ...
    • Countervailing effects of income, air pollution, smoking, and obesity on aging and life expectancy: population-based study of U.S. Counties 

      Allen, Ryan T.; Hales, Nicholas M.; Baccarelli, Andrea; Jerrett, Michael; Ezzati, Majid; Dockery, Douglas W.; Pope, C. Arden (BioMed Central, 2016)
      Background: Income, air pollution, obesity, and smoking are primary factors associated with human health and longevity in population-based studies. These four factors may have countervailing impacts on longevity. This ...
    • Countries’ Biomedical Publications and Attraction Scores 

      Xu, Qinyi; Boggio, Andrea; Ballabeni, Andrea (F1000Research, 2014)
      Studying publication volumes at the country level is key to understanding and improving a country’s research system. PubMed is a public search engine of publications in all life sciences areas. Here, we show how this search ...
    • Covariate selection for association screening in multiphenotype genetic studies 

      Aschard, Hugues; Guillemot, Vincent; Vilhjalmsson, Bjarni; Patel, Chirag; Skurnik, David; Ye, Chun J; Wolpin, Brian; Kraft, Phillip; Zaitlen, Noah (Springer Science and Business Media LLC, 2017-10-16)
    • Covariation in the socioeconomic determinants of self rated health and happiness: a multivariate multilevel analysis of individuals and communities in the USA 

      Subramanian, S.; Kim, D.; Kawachi, I. (BMJ Publishing Group, 2005)
      Objective: To investigate individual level determinants of self rated health and happiness, as well as the extent of community level covariation in health and happiness.Design: Multivariate multilevel regression analysis ...
    • Coverage and timing of antenatal care among poor women in 6 Mesoamerican countries 

      Dansereau, Emily; McNellan, Claire R.; Gagnier, Marielle C.; Desai, Sima S.; Haakenstad, Annie; Johanns, Casey K.; Palmisano, Erin B.; Ríos-Zertuche, Diego; Schaefer, Alexandra; Zúñiga-Brenes, Paola; Hernandez, Bernardo; Iriarte, Emma; Mokdad, Ali H. (BioMed Central, 2016)
      Background: Poor women in the developing world have a heightened need for antenatal care (ANC) but are often the least likely to attend it. This study examines factors associated with the number and timing of ANC visits ...
    • Coverage recommendations for methylation analysis by whole genome bisulfite sequencing 

      Ziller, Michael J.; Hansen, Kasper D.; Meissner, Alexander; Aryee, Martin J. (2014)
      Whole genome bisulfite sequencing (WGBS) allows genome-wide DNA methylation profiling but the associated high sequencing costs continue to limit its widespread application. We utilized several high coverage reference data ...
    • COVID-19 care in India: the course to self-reliance 

      Balsari, Satchit; Sange, Mansoor; Udwadia, Zarir (Elsevier BV, 2020-08)
    • COVID-19: US federal accountability for entry, spread, and inequities—lessons for the future 

      Hanage, William; Testa, Christian; Chen, Jarvis; Davis, Letitia; Pechter, Elise; Seminario, Peg; Santillana, Mauricio; Krieger, Nancy (Springer Science and Business Media LLC, 2020-11)
      The United States (US) has been among those nations most severely affected by the first—and subsequent—phases of the pandemic of COVID-19, the disease caused by SARS-CoV-2. With only 4% of the worldwide population, the US ...
    • Cox Model Setup: Garshick et al. Respond 

      Garshick, Eric; Laden, Francine; Hart, Jaime Elizabeth; Davis, Mary Elizabeth; Eisen, Ellen A.; Smith, Thomas J. (National Institute of Environmental Health Sciences, 2012)
    • CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer 

      Ogino, Shuji; Nosho, Katsuhiko; Kirkner, Gregory J.; Kawasaki, Takako; Meyerhardt, Jeffrey A.; Loda, Massimo; Giovannucci, Edward L.; Fuchs, Charles S. (BMJ Publishing Group, 2009)
      Background: The CpG island methylator phenotype (CIMP), characterised by widespread promoter methylation, is associated with microsatellite instability (MSI) and BRAF mutation in colorectal cancer. The independent effect ...
    • CR Cistrome: a ChIP-Seq database for chromatin regulators and histone modification linkages in human and mouse 

      Wang, Qixuan; Huang, Jinyan; Sun, Hanfei; Liu, Jing; Wang, Juan; Wang, Qian; Qin, Qian; Mei, Shenglin; Zhao, Chengchen; Yang, Xiaoqin; Liu, X. Shirley; Zhang, Yong (Oxford University Press, 2013)
      Diversified histone modifications (HMs) are essential epigenetic features. They play important roles in fundamental biological processes including transcription, DNA repair and DNA replication. Chromatin regulators (CRs), ...
    • Craniofacial features as assessed by lateral cephalometric measurements in children with Down syndrome 

      Allareddy, Veerasathpurush; Ching, Nicholas; Macklin, Eric A.; Voelz, Lauren; Weintraub, Gil; Davidson, Emily; Prock, Lisa Albers; Rosen, Dennis; Brunn, Richard; Skotko, Brian G. (Springer Berlin Heidelberg, 2016)
      Objective: The objective of the present study is to examine the craniofacial development of patients with Down syndrome (DS) and compare them with a neurotypical population. Methods: This study is a cross-sectional analysis ...
    • Craniofacial Measurements of Donors and Recipients Correlate with Aesthetic Outcome in Virtual Face Transplantation 

      S. Wallins, Joseph; Chandawarkar, Akash A.; Dobry, Allison; Diaz-Siso, J. Rodrigo; Bueno, Ericka M.; Caterson, Edward J.; Jania, Camille; Hevelone, Nathanael D.; Lipsitz, Stuart R.; Mukundan, Srinivasan; Pomahac, Bohdan (Wolters Kluwer Health, 2015)
      Background: Face transplantation is an increasingly feasible option for patients with severe disfigurement. Donors and recipients are currently matched based on immune compatibility, skin characteristics, age, and gender. ...
    • A Cricket Gene Index: A Genomic Resource for Studying Neurobiology, Speciation, and Molecular Evolution 

      Danley, Patrick D; Mullen, Sean P; Liu, Fenglong; Nene, Vishvanath; Quackenbush, John; Shaw, Kerry L (BioMed Central, 2007)
      Background: As the developmental costs of genomic tools decline, genomic approaches to nonmodel systems are becoming more feasible. Many of these systems may lack advanced genetic tools but are extremely valuable models ...
    • CRISPR-Induced Distributed Immunity in Microbial Populations 

      Childs, Lauren M.; England, Whitney E.; Young, Mark J.; Weitz, Joshua S.; Whitaker, Rachel J. (Public Library of Science, 2014)
      In bacteria and archaea, viruses are the primary infectious agents, acting as virulent, often deadly pathogens. A form of adaptive immune defense known as CRISPR-Cas enables microbial cells to acquire immunity to viral ...
    • Criteria for assessing high-priority drug-drug interactions for clinical decision support in electronic health records 

      Phansalkar, Shobha; Desai, Amrita; Choksi, Anish; Yoshida, Eileen; Doole, John; Czochanski, Melissa; Tucker, Alisha D; Middleton, Blackford; Bell, Douglas; Bates, David W (BioMed Central, 2013)
      Background: High override rates for drug-drug interaction (DDI) alerts in electronic health records (EHRs) result in the potentially dangerous consequence of providers ignoring clinically significant alerts. Lack of ...