Browsing SPH Scholarly Articles by Title

Now showing items 1424-1443 of 6362

    • A Critical Role of Fatty Acid Binding Protein 4 and 5 (FABP4/5) in the Systemic Response to Fasting 

      Syamsunarno, Mas Rizky A. A.; Iso, Tatsuya; Hanaoka, Hirofumi; Yamaguchi, Aiko; Obokata, Masaru; Koitabashi, Norimichi; Goto, Kosaku; Hishiki, Takako; Nagahata, Yoshiko; Matsui, Hiroki; Sano, Motoaki; Kobayashi, Masaki; Kikuchi, Osamu; Sasaki, Tsutomu; Maeda, Kazuhisa; Murakami, Masami; Kitamura, Tadahiro; Suematsu, Makoto; YoshitoTsushima; Endo, Keigo; Hotamisligil, Gökhan S.; Kurabayashi, Masahiko (Public Library of Science, 2013)
      During prolonged fasting, fatty acid (FA) released from adipose tissue is a major energy source for peripheral tissues, including the heart, skeletal muscle and liver. We recently showed that FA binding protein 4 (FABP4) ...

    • A cross sectional study of anemia and iron deficiency as risk factors for arsenic-induced skin lesions in Bangladeshi women 

      Kile, Molly L.; Faraj, Joycelyn M.; Ronnenberg, Alayne G.; Quamruzzaman, Quazi; Rahman, Mahmudar; Mostofa, Golam; Afroz, Sakila; Christiani, David C. (BioMed Central, 2016)
      Background: In the Ganges Delta, chronic arsenic poisoning is a health concern affecting millions of people who rely on groundwater as their potable water source. The prevalence of anemia is also high in this region, ...

    • Cross-biome comparison of microbial association networks 

      Faust, Karoline; Lima-Mendez, Gipsi; Lerat, Jean-Sébastien; Sathirapongsasuti, Jarupon F.; Knight, Rob; Huttenhower, Curtis; Lenaerts, Tom; Raes, Jeroen (Frontiers Media S.A., 2015)
      Clinical and environmental meta-omics studies are accumulating an ever-growing amount of microbial abundance data over a wide range of ecosystems. With a sufficiently large sample number, these microbial communities can ...

    • Cross-cancer genome-wide analysis of lung, ovary, breast, prostate and colorectal cancer reveals novel pleiotropic associations 

      Fehringer, Gordon; Kraft, Peter; Pharoah, Paul; Eeles, Rosalind; Chatterjee, Nilanjan; Schumacher, Fred; Schildkraut, Joellen; Lindström, Sara; Brennan, Paul; Bickeböller, Heike; Houlston, Richard; Landi, Maria Teresa; Caporaso, Neil; Risch, Angela; Olama, Ali Amin Al; Berndt, Sonja; Giovannucci, Edward; Grönberg, Henrik; Kote-Jarai, Zsofia; Ma, Jing; Muir, Kenneth; Stampfer, Meir; Stevens, Victoria; Wiklund, Fredrik; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Goode, Ellen; Permuth, Jennifer; Risch, Harvey; Reid, Brett; Bezieau, Stephane; Brenner, Hermann; Chan, Andrew; Chang-Claude, Jenny; Hudson, Thomas; Kocarnik, Jonathan; Newcomb, Polly; Schoen, Robert; Slattery, Martha; White, Emily; Adank, Muriel; Ahsan, Habibul; Aittomäki, Kristiina; Baglietto, Laura; Blomquist, Carl; Canzian, Federico; Czene, Kamila; dos-Santos-Silva, Isabel; Eliassen, A. Heather; Figueroa, Jonine; Flesch-Janys, Dieter; Fletcher, Olivia; Garcia-Closas, Montserrat; Gaudet, Mia; Johnson, Nichola; Hall, Per; Hazra, Aditi; Hein, Rebecca; Hofman, Albert; Hopper, John; Irwanto, Astrid; Johansson, Mattias; Kaaks, Rudolf; Kibriya, Muhammad; Lichtner, Peter; Liu, Jianjun; Lund, Eiliv; Makalic, Enes; Meindl, Alfons; Müller-Myhsok, Bertram; Muranen, Taru; Nevanlinna, Heli; Peeters, Petra; Peto, Julian; Prentice, Ross; Rahman, Nazneen; Sanchez, Maria Jose; Schmidt, Daniel; Schmutzler, Rita; Southey, Melissa; Tamimi, Rulla; Travis, Ruth; Turnbull, Clare; Uitterlinden, Andre; Wang, Zhaoming; Whittemore, Alice; Yang, Xiaohong; Zheng, Wei; Rafnar, Thorunn; Gudmundsson, Julius; Stacey, Simon; Stefansson, Kari; Sulem, Patrick; Chen, Y. Ann; Tyrer, Jonathan; Christiani, David; Wei, Yongyue; Shen, Hongbing; Hu, Zhibin; Shu, Xiao-Ou; Shiraishi, Kouya (American Association for Cancer Research, 2016)
      Identifying genetic variants with pleiotropic associations can uncover common pathways influencing multiple cancers. We took a two-stage approach to conduct genome-wide association studies for lung, ovary, breast, prostate, ...

    • Cross-kingdom patterns of alternative splicing and splice recognition 

      McGuire, Abigail M; Pearson, Matthew D; Neafsey, Daniel Edward; Galagan, James E (BioMed Central, 2008)
      Background: Variations in transcript splicing can reveal how eukaryotes recognize intronic splice sites. Retained introns (RIs) commonly appear when the intron definition (ID) mechanism of splice site recognition ...

    • Cross-national comparison of socioeconomic inequalities in obesity in the United States and Canada 

      Siddiqi, Arjumand; Brown, Rashida; Nguyen, Quynh C.; Loopstra, Rachel; Kawachi, Ichiro (BioMed Central, 2015)
      Introduction: Prior cross-national studies of socioeconomic inequalities in obesity have only compared summary indices of inequality but not specific, policy-relevant dimensions of inequality: (a) shape of the socioeconomic ...

    • Cross-National Variation in Glycemic Control and Diabetes-Related Distress Among East Asian Patients Using Insulin: Results from the MOSAIc Study 

      Matsuba, Ikuro; Sawa, Tasuku; Kawata, Takehiro; Kanamori, Akira; Jiang, Dingfeng; Machimura, Hideo; Takeda, Hiroshi; Han, Jeong Hee; Wang, Ke; Tanaka, Keiji; Shen, Li; Ajima, Miho; Kaneshiro, Mizuki; Kim, Sang-Wook; Umezawa, Shinichi; Asakura, Taro; Suzuki, Shuichi; Kim, Seoyoung C. (Springer Healthcare, 2016)
      Introduction: Guidelines recommend insulin progression for patients with type 2 diabetes (T2D) with inadequate glycemic control. The Multinational Observational Study Assessing Insulin use (MOSAIc [ClinicalTrials.gov ...

    • Cross-reactivity to human T-lymphotropic virus type III/lymphadenopathy-associated virus and molecular cloning of simian T-cell lymphotropic virus type III from African green monkeys. 

      Hirsch, V.; Riedel, N.; Kornfeld, H.; Kanki, Phyllis Jean; Essex, Myron Elmer; Mullins, J. I. (Proceedings of the National Academy of Sciences, 1986)
      Simian T-lymphotropic retroviruses with structural, antigenic, and cytopathic features similar to the etiologic agent of human acquired immunodeficiency syndrome, human T-lymphotropic virus type III/lymphadenopathy-associated ...

    • A cross-sectional study of secondhand smoke exposure and respiratory symptoms in non-current smokers in the U.S. trucking industry: SHS exposure and respiratory symptoms 

      Laden, Francine; Chiu, Yueh-Hsiu; Garshick, Eric; Hammond, S Katharine; Hart, Jaime Elizabeth (BioMed Central, 2013)
      Background: Previous studies have suggested associations of adult exposures to secondhand smoke (SHS) with respiratory symptoms, but no study has focused on blue-collar industrial environments. We assessed the association ...

    • A cross-sectional study of the identification of prevalent asthma and chronic obstructive pulmonary disease among initiators of long-acting β-agonists in health insurance claims data 

      Dore, David D; Ziyadeh, Najat; Cai, Bin; Clifford, C Robin; Norman, Heather; Seeger, John D (BioMed Central, 2014)
      Background: Claims data are potentially useful for identifying long-acting β-agonist (LABA) use by patients with asthma, a practice that is associated with increased mortality. We evaluated the accuracy of claims data for ...

    • A cross-sectional study on tobacco use and dependence among women: Does menthol matter? 

      Rosenbloom, Judith; Rees, Vaughan Wallis; Reid, Kathleen; Wong, Jeannie; Kinnunen, Taru Hannele (BioMed Central, 2012)
      Background: The question of whether mentholation of cigarettes enhances tobacco dependence has generated conflicting findings. Potential mediating factors in a putative relationship between menthol use and tobacco dependence ...

    • A cross-sectional survey of supports for evidence-informed decision-making in healthcare organisations: a research protocol 

      Ouimet, Mathieu; Lavis, John N; Léon, Grégory; Ellen, Moriah E; Bédard, Pierre-Olivier; Grimshaw, Jeremy M; Gagnon, Marie-Pierre (BioMed Central, 2014)
      Background: This protocol builds on the development of a) a framework that identified the various supports (i.e. positions, activities, interventions) that a healthcare organisation or health system can implement for ...

    • CRP gene variation and risk of community-acquired pneumonia 

      Mukamal, Kenneth J.; Pai, Jennifer K.; O'MEARA, Ellen S.; Tracy, Russell P.; Psaty, Bruce M.; Kuller, Lewis H.; Newman, Anne B.; Yende, Sachin; Curhan, Gary C.; Siscovick, David S.; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600 (2010)

    • The CRTC-1 transcriptional domain is required for COMPASS complex-mediated longevity in C. elegans 

      Silva-García, Carlos Giovanni; Heintz, Caroline; Prabhakar, Aditi; Morrow, Christopher S.; Pajuelo Torres, Lourdes; Sharma, Arpit; Liu, Jihe; Mair, William B. (Springer Science and Business Media LLC, 2023-11-09)
      Loss of function during ageing is accompanied by transcriptional drift, altering gene expression and contributing to a variety of age-related diseases. CREB-regulated transcriptional coactivators (CRTCs) have emerged as ...

    • Cumulative Community-Level Lead Exposure and Pulse Pressure: The Normative Aging Study 

      Perlstein, Todd Steven; Weuve, Jennifer Lynn; Schwartz, Joel David; Sparrow, David; Wright, Robert O.; Litonjua, Augusto Ampil; Nie, Huiling; Hu, Howard (National Institute of Environmental Health Sciences, 2007)
      Background: Pulse pressure increases with age in industrialized societies as a manifestation of arterial stiffening. Lead accumulates in the vasculature and is associated with vascular oxidative stress, which can promote ...

    • Cumulative Exposure to Lead in Relation to Cognitive Function in Older Women 

      Weuve, Jennifer Lynn; Korrick, Susan Abigail; Weisskopf, Marc G.; Ryan, Louise Marie; Schwartz, Joel David; Nie, Huiling; Grodstein, Francine; Hu, Howard (National Institute of Environmental Health Sciences, 2008)
      Background: Recent data indicate that chronic low-level exposure to lead is associated with accelerated declines in cognition in older age, but this has not been examined in women. Objective: We examined biomarkers of lead ...

    • Cumulative Lead Dose and Cognitive Function in Adults: A Review of Studies That Measured Both Blood Lead and Bone Lead 

      Shih, Regina A.; Hu, Howard; Weisskopf, Marc G.; Schwartz, Brian Elliott (National Institute of Environmental Health Sciences, 2006)
      Objective: We review empirical evidence for the relations of recent and cumulative lead dose with cognitive function in adults. Data Sources: A systematic search of electronic databases resulted in 21 environmental and ...

    • Cumulative Lead Exposure and Age at Menopause in the Nurses’ Health Study Cohort 

      Eum, Ki-Do; Weisskopf, Marc G.; Nie, Linda H.; Hu, Howard; Korrick, Susan A. (National Institute of Environmental Health Sciences, 2014)
      Background: Early menopause has been associated with many adverse health outcomes, including increased risk of cardiovascular disease morbidity and mortality. Lead has been found to be adversely associated with female ...

    • Cumulative Lead Exposure and Tooth Loss in Men: The Normative Aging Study 

      Arora, Manish; Weuve, Jennifer Lynn; Weisskopf, Marc G.; Sparrow, David; Nie, Huiling; Garcia, Raul I.; Hu, Howard (National Institute of Environmental Health Sciences, 2009)
      Background: Individuals previously exposed to lead remain at risk because of endogenous release of lead stored in their skeletal compartments. However, it is not known if long-term cumulative lead exposure is a risk factor ...

    • Cumulative Risk of Colon Cancer up to Age 70 Years by Risk Factor Status Using Data From the Nurses’ Health Study 

      Wei, Esther K.; Colditz, Graham A.; Giovannucci, Edward L.; Fuchs, Charles S.; Rosner, Bernard A. (Oxford University Press, 2009)
      The authors developed a comprehensive model of colon cancer incidence that allows for nonproportional hazards and accounts for the temporal nature of risk factors. They estimated relative risk based on cumulative incidence ...