Browsing SPH Scholarly Articles by Title

Now showing items 2059-2078 of 6362

    • Enhanced methods for unbiased deep sequencing of Lassa and Ebola RNA viruses from clinical and biological samples 

      Matranga, Christian B; Andersen, Kristian G; Winnicki, Sarah; Busby, Michele; Gladden, Adrianne D; Tewhey, Ryan; Stremlau, Matthew; Berlin, Aaron; Gire, Stephen K; England, Eleina; Moses, Lina M; Mikkelsen, Tarjei S; Odia, Ikponmwonsa; Ehiane, Philomena E; Folarin, Onikepe; Goba, Augustine; Kahn, S Humarr; Grant, Donald S; Honko, Anna; Hensley, Lisa; Happi, Christian; Garry, Robert F; Malboeuf, Christine M; Birren, Bruce W; Gnirke, Andreas; Levin, Joshua Z; Sabeti, Pardis C (BioMed Central, 2014)
      We have developed a robust RNA sequencing method for generating complete de novo assemblies with intra-host variant calls of Lassa and Ebola virus genomes in clinical and biological samples. Our method uses targeted RNase ...

    • Enhancer RNAs participate in androgen receptor-driven looping that selectively enhances gene activation 

      Hsieh, Chen-Lin; Fei, Teng; Chen, Yiwen; Li, Tiantian; Gao, Yanfei; Wang, Xiaodong; Sun, Tong; Sweeney, Christopher J; Lee, Gwo-Shu Mary; Chen, Shaoyong; Balk, Steven Paul; Liu, Xiaole (Shirley) Shirley; Brown, Myles Avery; Kantoff, Philip Wayne (Proceedings of the National Academy of Sciences, 2014)
      The androgen receptor (AR) is a key factor that regulates the behavior and fate of prostate cancer cells. The AR-regulated network is activated when AR binds enhancer elements and modulates specific enhancer–promoter ...

    • Enhancing disease surveillance with novel data streams: challenges and opportunities 

      Althouse, Benjamin M; Scarpino, Samuel V; Meyers, Lauren Ancel; Ayers, John W; Bargsten, Marisa; Baumbach, Joan; Brownstein, John S; Castro, Lauren; Clapham, Hannah; Cummings, Derek AT; Del Valle, Sara; Eubank, Stephen; Fairchild, Geoffrey; Finelli, Lyn; Generous, Nicholas; George, Dylan; Harper, David R; Hébert-Dufresne, Laurent; Johansson, Michael A; Konty, Kevin; Lipsitch, Marc; Milinovich, Gabriel; Miller, Joseph D; Nsoesie, Elaine O; Olson, Donald R; Paul, Michael; Polgreen, Philip M; Priedhorsky, Reid; Read, Jonathan M; Rodríguez-Barraquer, Isabel; Smith, Derek J; Stefansen, Christian; Swerdlow, David L; Thompson, Deborah; Vespignani, Alessandro; Wesolowski, Amy (2016)
      Novel data streams (NDS), such as web search data or social media updates, hold promise for enhancing the capabilities of public health surveillance. In this paper, we outline a conceptual framework for integrating NDS ...

    • Enhancing Situational Awareness to Prevent Infectious Disease Outbreaks from Becoming Catastrophic 

      Lipsitch, Marc; Santillana, Mauricio (Springer Berlin Heidelberg, 2019)
      Catastrophic epidemics, if they occur, will very likely start from localized and far smaller (noncatastrophic) outbreaks that grow into much greater threats. One key bulwark against this outcome is the ability of governments ...

    • Enhancing the quality of international orthopedic medical mission trips using the blue distinction criteria for knee and hip replacement centers 

      Dempsey, Kyle E; Ghazinouri, Roya; Diez, Desiree; Alcantara, Luis; Beagan, Carolyn; Aggouras, Barbara; Hoagland, Monica; Thornhill, Thomas S; Katz, Jeffrey N (BioMed Central, 2013)
      Background: Several organizations seek to address the growing burden of arthritis in developing countries by providing total joint replacements (TJR) to patients with advanced arthritis who otherwise would not have access ...

    • The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data 

      Thompson, Paul M.; Stein, Jason L.; Medland, Sarah E.; Hibar, Derrek P.; Vasquez, Alejandro Arias; Renteria, Miguel E.; Toro, Roberto; Jahanshad, Neda; Schumann, Gunter; Franke, Barbara; Wright, Margaret J.; Martin, Nicholas G.; Agartz, Ingrid; Alda, Martin; Alhusaini, Saud; Almasy, Laura; Almeida, Jorge; Alpert, Kathryn; Andreasen, Nancy C.; Andreassen, Ole A.; Apostolova, Liana G.; Appel, Katja; Armstrong, Nicola J.; Aribisala, Benjamin; Bastin, Mark E.; Bauer, Michael; Bearden, Carrie E.; Bergmann, Ørjan; Binder, Elisabeth B.; Blangero, John; Bockholt, Henry J.; Bøen, Erlend; Bois, Catherine; Boomsma, Dorret I.; Booth, Tom; Bowman, Ian J.; Bralten, Janita; Brouwer, Rachel M.; Brunner, Han G.; Brohawn, David G.; Buckner, Randy L.; Buitelaar, Jan; Bulayeva, Kazima; Bustillo, Juan R.; Calhoun, Vince D.; Cannon, Dara M.; Cantor, Rita M.; Carless, Melanie A.; Caseras, Xavier; Cavalleri, Gianpiero L.; Chakravarty, M. Mallar; Chang, Kiki D.; Ching, Christopher R. K.; Christoforou, Andrea; Cichon, Sven; Clark, Vincent P.; Conrod, Patricia; Coppola, Giovanni; Crespo-Facorro, Benedicto; Curran, Joanne E.; Czisch, Michael; Deary, Ian J.; de Geus, Eco J. C.; den Braber, Anouk; Delvecchio, Giuseppe; Depondt, Chantal; de Haan, Lieuwe; de Zubicaray, Greig I.; Dima, Danai; Dimitrova, Rali; Djurovic, Srdjan; Dong, Hongwei; Donohoe, Gary; Duggirala, Ravindranath; Dyer, Thomas D.; Ehrlich, Stefan; Ekman, Carl Johan; Elvsåshagen, Torbjørn; Emsell, Louise; Erk, Susanne; Espeseth, Thomas; Fagerness, Jesen; Fears, Scott; Fedko, Iryna; Fernández, Guillén; Fisher, Simon E.; Foroud, Tatiana; Fox, Peter T.; Francks, Clyde; Frangou, Sophia; Frey, Eva Maria; Frodl, Thomas; Frouin, Vincent; Garavan, Hugh; Giddaluru, Sudheer; Glahn, David C.; Godlewska, Beata; Goldstein, Rita Z.; Gollub, Randy L.; Grabe, Hans J.; Grimm, Oliver; Gruber, Oliver; Guadalupe, Tulio; Gur, Raquel E.; Gur, Ruben C.; Göring, Harald H. H.; Hagenaars, Saskia; Hajek, Tomas; Hall, Geoffrey B.; Hall, Jeremy; Hardy, John; Hartman, Catharina A.; Hass, Johanna; Hatton, Sean N.; Haukvik, Unn K.; Hegenscheid, Katrin; Heinz, Andreas; Hickie, Ian B.; Ho, Beng-Choon; Hoehn, David; Hoekstra, Pieter J.; Hollinshead, Marisa; Holmes, Avram J.; Homuth, Georg; Hoogman, Martine; Hong, L. Elliot; Hosten, Norbert; Hottenga, Jouke-Jan; Hulshoff Pol, Hilleke E.; Hwang, Kristy S.; Jack, Clifford R.; Jenkinson, Mark; Johnston, Caroline; Jönsson, Erik G.; Kahn, René S.; Kasperaviciute, Dalia; Kelly, Sinead; Kim, Sungeun; Kochunov, Peter; Koenders, Laura; Krämer, Bernd; Kwok, John B. J.; Lagopoulos, Jim; Laje, Gonzalo; Landen, Mikael; Landman, Bennett A.; Lauriello, John; Lawrie, Stephen M.; Lee, Phil H.; Le Hellard, Stephanie; Lemaître, Herve; Leonardo, Cassandra D.; Li, Chiang-shan; Liberg, Benny; Liewald, David C.; Liu, Xinmin; Lopez, Lorna M.; Loth, Eva; Lourdusamy, Anbarasu; Luciano, Michelle; Macciardi, Fabio; Machielsen, Marise W. J.; MacQueen, Glenda M.; Malt, Ulrik F.; Mandl, René; Manoach, Dara S.; Martinot, Jean-Luc; Matarin, Mar; Mather, Karen A.; Mattheisen, Manuel; Mattingsdal, Morten; Meyer-Lindenberg, Andreas; McDonald, Colm; McIntosh, Andrew M.; McMahon, Francis J.; McMahon, Katie L.; Meisenzahl, Eva; Melle, Ingrid; Milaneschi, Yuri; Mohnke, Sebastian; Montgomery, Grant W.; Morris, Derek W.; Moses, Eric K.; Mueller, Bryon A.; Muñoz Maniega, Susana; Mühleisen, Thomas W.; Müller-Myhsok, Bertram; Mwangi, Benson; Nauck, Matthias; Nho, Kwangsik; Nichols, Thomas E.; Nilsson, Lars-Göran; Nugent, Allison C.; Nyberg, Lars; Olvera, Rene L.; Oosterlaan, Jaap; Ophoff, Roel A.; Pandolfo, Massimo; Papalampropoulou-Tsiridou, Melina; Papmeyer, Martina; Paus, Tomas; Pausova, Zdenka; Pearlson, Godfrey D.; Penninx, Brenda W.; Peterson, Charles P.; Pfennig, Andrea; Phillips, Mary; Pike, G. Bruce; Poline, Jean-Baptiste; Potkin, Steven G.; Pütz, Benno; Ramasamy, Adaikalavan; Rasmussen, Jerod; Rietschel, Marcella; Rijpkema, Mark; Risacher, Shannon L.; Roffman, Joshua L.; Roiz-Santiañez, Roberto; Romanczuk-Seiferth, Nina; Rose, Emma J.; Royle, Natalie A.; Rujescu, Dan; Ryten, Mina; Sachdev, Perminder S.; Salami, Alireza; Satterthwaite, Theodore D.; Savitz, Jonathan; Saykin, Andrew J.; Scanlon, Cathy; Schmaal, Lianne; Schnack, Hugo G.; Schork, Andrew J.; Schulz, S. Charles; Schür, Remmelt; Seidman, Larry; Shen, Li; Shoemaker, Jody M.; Simmons, Andrew; Sisodiya, Sanjay M.; Smith, Colin; Smoller, Jordan W.; Soares, Jair C.; Sponheim, Scott R.; Sprooten, Emma; Starr, John M.; Steen, Vidar M.; Strakowski, Stephen; Strike, Lachlan; Sussmann, Jessika; Sämann, Philipp G.; Teumer, Alexander; Toga, Arthur W.; Tordesillas-Gutierrez, Diana; Trabzuni, Daniah; Trost, Sarah; Turner, Jessica; Van den Heuvel, Martijn; van der Wee, Nic J.; van Eijk, Kristel; van Erp, Theo G. M.; van Haren, Neeltje E. M.; van ‘t Ent, Dennis; van Tol, Marie-Jose; Valdés Hernández, Maria C.; Veltman, Dick J.; Versace, Amelia; Völzke, Henry; Walker, Robert; Walter, Henrik; Wang, Lei; Wardlaw, Joanna M.; Weale, Michael E.; Weiner, Michael W.; Wen, Wei; Westlye, Lars T.; Whalley, Heather C.; Whelan, Christopher D.; White, Tonya; Winkler, Anderson M.; Wittfeld, Katharina; Woldehawariat, Girma; Wolf, Christiane; Zilles, David; Zwiers, Marcel P.; Thalamuthu, Anbupalam; Schofield, Peter R.; Freimer, Nelson B.; Lawrence, Natalia S.; Drevets, Wayne (Springer US, 2014)
      The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from 70 institutions worldwide. ...

    • Ensuring It Works: A Community-Based Approach to HIV Prevention Intervention Development for Men Who Have Sex with Men in Chennai, India 

      Thomas, Beena; Mimiaga, Matthew James; Mayer, Kenneth Hugh; Closson, Elizabeth F.; Johnson, Carey V.; Menon, Sunil; Mani, Jamuna; Vijaylakshmi, R.; Dilip, Meenalochini; Betancourt, Theresa Stichick; Safren, Steven Alex (Guilford Publications, 2012)
      Men who have sex with men (MSM) in India have an HIV seroprevalence 22 times greater than the country’s general population and face unique challenges that may hinder the effectiveness of current HIV prevention efforts. To ...

    • Ensuring Quality in AFRINEST and SATT: Clinical Standardization and Monitoring 

      Wall, Stephen N.; Mazzeo, Corinne I.; Adejuyigbe, Ebunoluwa A.; Ayede, Adejumoke I.; Bahl, Rajiv; Baqui, Abdullah H.; Blackwelder, William C.; Brandes, Neal; Darmstadt, Gary L.; Esamai, Fabian; Hibberd, Patricia L.; Jacobs, Marian; Klein, Jerome O.; Mwinga, Kasonde; Rollins, Nigel Campbell; Saloojee, Haroon; Tshefu, Antoinette Kitoto; Wammanda, Robinson D.; Zaidi, Anita K. M.; Qazi, Shamim Ahmad (Williams & Wilkins, 2013)
      Background: Three randomized open-label clinical trials [Simplified Antibiotic Therapy Trial (SATT) Bangladesh, SATT Pakistan and African Neonatal Sepsis Trial (AFRINEST)] were developed to test the equivalence of simplified ...

    • Entomologic and Serologic Evidence of Zoonotic Transmission of Babesia microti, Eastern Switzerland 

      Foppa, Ivo M.; Krause, Peter J.; Spielman, Andrew; Goethert, Heidi; Gern, Lise; Brand, Brigit; Telford, Sam R. (Centers for Disease Control and Prevention, 2002)
      We evaluated human risk for infection with Babesia microti at a site in eastern Switzerland where several B. microti–infected nymphal Ixodes ricinus ticks had been found. DNA from pooled nymphal ticks amplified by polymerase ...

    • Enumeration of CD4+ T-Cells Using a Portable Microchip Count Platform in Tanzanian HIV-Infected Patients 

      Moon, SangJun; Gurkan, Umut; Blander, Jeffrey; Fawzi, Wafaie W.; Aboud, Said; Mugusi, Ferdinand; Kuritzkes, Daniel Robert; Demirci, Utkan (Public Library of Science (PLoS), 2011)
      Background CD4+ T-lymphocyte count (CD4 count) is a standard method used to monitor HIV-infected patients during anti-retroviral therapy (ART). The World Health Organization (WHO) has pointed out or recommended that a ...

    • Environment and Brain Development: Challenges in the Global Context 

      Julvez, Jordi; Paus, Tomas; Bellinger, David C; Eskenazi, Brenda; Tiemeier, Henning; Pearce, Neil; Ritz, Beate; White, Tonya; Ramchandani, Paul; Gispert, Juan; Desrivières, Sylvane; Brouwer, Rachel; Boucher, Olivier; Alemany, Silvia; López-Vicente, Mónica; Suades-González, Elisabeth; Forns, Joan; Grandjean, Philippe; Sunyer, Jordi (S. Karger AG, 2015)

    • Environment and Obesity in the National Children's Study 

      Trasande, Leonardo; Cronk, Chris; Durkin, Maureen; Weiss, Marianne; Schoeller, Dale A.; Gall, Elizabeth A.; Hewitt, Jeanne B.; Carrel, Aaron L.; Landrigan, Philip J.; Gillman, Matthew William (National Institute of Environmental Health Sciences, 2008)
      Objective: In this review we describe the approach taken by the National Children’s Study (NCS), a 21-year prospective study of 100,000 American children, to understanding the role of environmental factors in the development ...

    • Environmental Chemicals in Urine and Blood: Improving Methods for Creatinine and Lipid Adjustment 

      O’Brien, Katie M.; Upson, Kristen; Cook, Nancy R.; Weinberg, Clarice R. (National Institute of Environmental Health Sciences, 2015)
      Background: Investigators measuring exposure biomarkers in urine typically adjust for creatinine to account for dilution-dependent sample variation in urine concentrations. Similarly, it is standard to adjust for serum ...

    • Environmental Exposure to Polychlorinated Biphenyls and p,p´-DDE and Sperm Sex-Chromosome Disomy 

      McAuliffe, Megan E.; Williams, Paige L.; Korrick, Susan Abigail; Altshul, Larisa M.; Perry, Melissa J. (National Institute of Environmental Health Sciences, 2012)
      Background: Chromosomal abnormalities contribute substantially to reproductive problems, but the role of environmental risk factors has received little attention. Objectives: We evaluated the association of polychlorinated ...

    • Environmental Health: the First Five Years 

      Grandjean, Philippe; Ozonoff, David (BioMed Central, 2007)
      Environmental Health is now firmly established as a major venue for publishing in the field of environmental health. While remaining selective in our acceptances – of the 217 manuscripts that we have processed by June 2007, ...

    • Environmental Mold and Mycotoxin Exposures Elicit Specific Cytokine and Chemokine Responses 

      Rosenblum Lichtenstein, Jamie H.; Hsu, Yi-Hsiang; Gavin, Igor M.; Donaghey, Thomas C.; Molina, Ramon M.; Thompson, Khristy J.; Chi, Chih-Lin; Gillis, Bruce S.; Brain, Joseph D. (Public Library of Science, 2015)
      Background: Molds can cause respiratory symptoms and asthma. We sought to use isolated peripheral blood mononuclear cells (PBMCs) to understand changes in cytokine and chemokine levels in response to mold and mycotoxin ...

    • Environmental Organochlorines and Semen Quality: Results of a Pilot Study 

      Hauser, Russ B.; Altshul, Larisa M.; Chen, Zuying; Ryan, Louise Marie; Overstreet, James; Schiff, Isaac; Christiani, David C. (National Institute of Environmental Health Sciences, 2002)
      There have been numerous studies that suggest that sperm concentrations (sperm counts) are declining in men. However, other studies suggest that sperm counts are not declining or may be increasing in some areas. Although ...

    • Environmental Profile of a Community's Health (EPOCH): An Instrument to Measure Environmental Determinants of Cardiovascular Health in Five Countries 

      Chow, Clara K.; Lock, Karen; Madhavan, Manisha; Corsi, Daniel J.; Gilmore, Anna B.; Subramanian, S.V. Venkata; Li, Wei; Swaminathan, Sumathi; Lopez-Jaramillo, Patricio; Avezum, Alvaro; Lear, Scott A.; Dagenais, Gilles; Teo, Koon; McKee, Martin; Yusuf, Salim (Public Library of Science (PLoS), 2010)
      Background The environment in which people live is known to be important in influencing diet, physical activity, smoking, psychosocial and other risk factors for cardiovascular (CV) disease. However no instrument exists ...

    • Environmental Profile of a Community’s Health (EPOCH): An Ecometric Assessment of Measures of the Community Environment Based on Individual Perception 

      Corsi, Daniel J.; Subramanian, S.V. Venkata; McKee, Martin; Li, Wei; Swaminathan, Sumathi; Lopez-Jaramillo, Patricio; Avezum, Alvaro; Lear, Scott A.; Dagenais, Gilles; Rangarajan, Sumathy; Teo, Koon; Yusuf, Salim; Chow, Clara K. (Public Library of Science, 2012)
      Background: Public health research has turned towards examining upstream, community-level determinants of cardiovascular disease risk factors. Objective measures of the environment, such as those derived from direct ...

    • Environmental Susceptibility of the Sperm Epigenome During Windows of Male Germ Cell Development 

      Wu, Haotian; Hauser, Russ; Krawetz, Stephen A.; Pilsner, J. Richard (Springer International Publishing, 2015)
      Male germ cells require multiple epigenetic reprogramming events during their lifespan to achieve reproductive capacity. An emerging body of compelling data demonstrates that environmental exposures can be embodied within ...