Browsing SPH Scholarly Articles by Title

Now showing items 216-235 of 6362

    • Advances in the Science, Treatment, and Prevention of the Disease of Obesity: Reflections From a Diabetes Care Editors’ Expert Forum 

      Cefalu, William T.; Bray, George A.; Home, Philip D.; Garvey, W. Timothy; Klein, Samuel; Pi-Sunyer, F. Xavier; Hu, Frank B.; Raz, Itamar; Van Gaal, Luc; Wolfe, Bruce M.; Ryan, Donna H. (American Diabetes Association, 2015)
      As obesity rates increase, so too do the risks of type 2 diabetes, cardiovascular disease, and numerous other detrimental conditions. The prevalence of obesity in U.S. adults more than doubled between 1980 and 2010, from ...

    • Advances in translational bioinformatics facilitate revealing the landscape of complex disease mechanisms 

      Yang, Jack Y; Dunker, A Keith; Liu, Jun S; Qin, Xiang; Arabnia, Hamid R; Yang, William; Niemierko, Andrzej; Chen, Zhongxue; Luo, Zuojie; Wang, Liangjiang; Liu, Yunlong; Xu, Dong; Deng, Youping; Tong, Weida; Yang, Mary Qu (BioMed Central, 2014)
      Advances of high-throughput technologies have rapidly produced more and more data from DNAs and RNAs to proteins, especially large volumes of genome-scale data. However, connection of the genomic information to cellular ...

    • Advancing Survivors’ Knowledge (ASK) about skin cancer study: study protocol for a randomized controlled trial 

      Daniel, Casey L; Armstrong, Gregory T; Keske, Robyn R; Davine, Jessica A; McDonald, Aaron J; Sprunck-Harrild, Kim M; Coleman, Catherine; Haneuse, Sebastien J; Mertens, Ann C; Emmons, Karen M; Marghoob, Ashfaq A; Elkin, Elena B; Dusza, Stephen W; Robison, Leslie L; Geller, Alan C (BioMed Central, 2015)
      Background: Advances in treatment have increased childhood cancer 5-year survival rates to greater than 80%. However, children previously treated with radiation are at significantly increased risk of developing subsequent ...

    • Advancing the field of health systems research synthesis 

      Langlois, Etienne V.; Ranson, Michael K.; Bärnighausen, Till; Bosch-Capblanch, Xavier; Daniels, Karen; El-Jardali, Fadi; Ghaffar, Abdul; Grimshaw, Jeremy; Haines, Andy; Lavis, John N.; Lewin, Simon; Meng, Qingyue; Oliver, Sandy; Pantoja, Tomás; Straus, Sharon; Shemilt, Ian; Tovey, David; Tugwell, Peter; Waddington, Hugh; Wilson, Mark; Yuan, Beibei; Røttingen, John-Arne (BioMed Central, 2015)
      Those planning, managing and working in health systems worldwide routinely need to make decisions regarding strategies to improve health care and promote equity. Systematic reviews of different kinds can be of great help ...

    • Advancing the Science of Developmental Neurotoxicity (DNT): Testing for Better Safety Evaluation 

      Bal-Price, Anna; Coecke, Sandra; Crofton, Kevin; Fritsche, Ellen; Goldberg, Alan; Grandjean, Philippe; Lein, Pamela; Li, Abby; Lucchini, Roberto; Mundy, William R.; Padilla, Stephanie; Persico, Antonio; Seiler, Andrea; Kreysa, Joachim (ALTEX Edition, 2012)

    • Adverse Drug Events in Ambulatory Care 

      Gandhi, Tejal; Weingart, Saul N.; Borus, Joshua; Seger, Andrew C; Peterson, Josh; Burdick, Elisabeth; Seger, Diane L.; Small, Kirstin; Federico, Frank; Leape, Lucian; Bates, David (Massachusetts Medical Society, 2003-04-17)
      Background: Adverse events related to drugs occur frequently among inpatients, and many of these events are preventable. However, few data are available on adverse drug events among outpatients. We conducted a study to ...

    • Adverse Effects of Methylmercury: Environmental Health Research Implications 

      Grandjean, Philippe; Satoh, Hiroshi; Murata, Katsuyuki; Eto, Komyo (National Institute of Environmental Health Sciences, 2010)
      Background: The scientific discoveries of health risks resulting from methylmercury exposure began in 1865 describing ataxia, dysarthria, constriction of visual fields, impaired hearing, and sensory disturbance as symptoms ...

    • The Affordable Care Act Has Led To Significant Gains In Health Insurance And Access To Care For Young Adults 

      Sommers, Benjamin Daniel; Buchmueller, Thomas; Decker, Sandra; Carey, Colleen; Kronick, Richard (Health Affairs (Project Hope), 2012)
      The Affordable Care Act enables young adults to remain as dependents on their parents’ health insurance until age twenty-six, and recent evidence suggests that as many as three million young adults have gained coverage as ...

    • Afghanistan's Ethnic Groups Share a Y-Chromosomal Heritage Structured by Historical Events 

      Haber, Marc; Platt, Daniel E.; Ashrafian Bonab, Maziar; Youhanna, Sonia C.; Soria-Hernanz, David F.; Martínez-Cruz, Begoña; Douaihy, Bouchra; Ghassibe-Sabbagh, Michella; Rafatpanah, Hoshang; Ghanbari, Mohsen; Whale, John; Balanovsky, Oleg; Wells, R. Spencer; Comas, David; Tyler-Smith, Chris; Zalloua, Pierre A.; The Genographic Consortium (Public Library of Science, 2012)
      Afghanistan has held a strategic position throughout history. It has been inhabited since the Paleolithic and later became a crossroad for expanding civilizations and empires. Afghanistan's location, history, and diverse ...

    • African Organization for Research and Training in Cancer: position and vision for cancer research on the African Continent 

      Ogunbiyi, J. Olufemi; Stefan, D. Cristina; Rebbeck, Timothy R. (BioMed Central, 2016)
      The African Organization for Research and training in Cancer (AORTIC) bases the following position statements on a critical appraisal of the state on cancer research and cancer care in Africa including information on the ...

    • After abduction: exploring access to reintegration programs and mental health status among young female abductees in Northern Uganda 

      Muldoon, Katherine A; Muzaaya, Godfrey; Betancourt, Theresa S; Ajok, Mirriam; Akello, Monica; Petruf, Zaira; Nguyen, Paul; Baines, Erin K; Shannon, Kate (BioMed Central, 2014)
      Background: Reintegration programs are commonly offered to former combatants and abductees to acquire civilian status and support services to reintegrate into post-conflict society. Among a group of young female abductees ...

    • Age and Gender Moderate the Impact of Early Palliative Care in Metastatic Non-Small Cell Lung Cancer 

      Nipp, Ryan D.; Greer, Joseph A.; El-Jawahri, Areej; Traeger, Lara; Gallagher, Emily R.; Park, Elyse R.; Jackson, Vicki A.; Pirl, William F.; Temel, Jennifer S. (AlphaMed Press, 2016)
      Background. Studies demonstrate that early palliative care (EPC) improves advanced cancer patients’ quality of life (QOL) and mood. However, it remains unclear whether the role of palliative care differs based upon patients’ ...

    • Age and sharing of needle injection equipment in a cohort of Massachusetts injection drug users: an observational study 

      Tassiopoulos, Katherine; Bernstein, Judith; Bernstein, Edward (BioMed Central, 2013)
      Background: Hepatitis C infection (HCV) among individuals aged 15–24 years has increased in Massachusetts, likely due to injection drug use. The prevalence of injection equipment sharing (sharing) and its association with ...

    • Age- and Serogroup-Related Differences in Observed Durations of Nasopharyngeal Carriage of Penicillin-Resistant Pneumococci 

      Högberg, Liselotte; Geli, Patricia; Ringberg, Håkan; Melander, Eva; Lipsitch, Marc; Ekdahl, Karl (American Society for Microbiology, 2007)
      Using data from an ongoing Swedish intervention project, the observed durations of nasopharyngeal carriage of penicillin-nonsusceptible Streptococcus pneumoniae (PNSP) (MIC of penicillin G of >= 0.5 mu g/ml) stratified ...

    • Age-associated NF-κB signaling in myofibers alters the satellite cell niche and re-strains muscle stem cell function 

      Oh, Juhyun; Sinha, Indranil; Tan, Kah Yong; Rosner, Bernard; Dreyfuss, Jonathan M.; Gjata, Ornela; Tran, Peter; Shoelson, Steven E.; Wagers, Amy J. (Impact Journals LLC, 2016)
      Skeletal muscle is a highly regenerative tissue, but muscle repair potential is increasingly compromised with advancing age. In this study, we demonstrate that increased NF-κB activity in aged muscle fibers contributes to ...

    • Age-Related Decline in Cardiorespiratory Fitness among Career Firefighters: Modification by Physical Activity and Adiposity 

      Baur, Dorothee Maria; Christophi, Costas A.; Cook, Earl F.; Kales, Stefanos Nicholas (Hindawi Publishing Corporation, 2012)
      Firefighting is a very hazardous occupation, and strenuous fire duties require high levels of physical fitness. In the general adult population, cardiorespiratory fitness (CRF) declines with aging. We sought to investigate ...

    • Age-Related Macular Degeneration and the Incidence of Cardiovascular Disease: A Systematic Review and Meta-Analysis 

      Wu, Juan; Uchino, Miki; Sastry, Srinivas M.; Schaumberg, Debra A. (Public Library of Science, 2014)
      Importance Research has indicated some shared pathogenic mechanisms between age-related macular degeneration (AMD) and cardiovascular disease (CVD). However, results from prior epidemiologic studies have been inconsistent ...

    • Age-Specific Immunoglobulin G (IgG) and IgA to Pneumococcal Protein Antigens in a Population in Coastal Kenya 

      Laine, C.; Mwangi, T.; Thompson, Claudette M.; Obiero, J.; Lipsitch, Marc; Scott, J. A. G. (American Society for Microbiology, 2004)
      Streptococcus pneumoniae is the primary etiological agent of community-acquired pneumonia and a major cause of meningitis and bacteremia. Three conserved pneumococcal proteins-pneumolysin, pneumococcal surface adhesin A ...

    • Age-specific prevalence of human papilloma virus infection among Nigerian women 

      Akarolo-Anthony, Sally N; Famooto, Ayo O; Dareng, Eileen O; Olaniyan, Olayinka B; Offiong, Richard; Wheeler, Cosette M; Adebamowo, Clement A (BioMed Central, 2014)
      Background: Inconsistent trends in HPV prevalence by age have been described in Africa. We examined the age prevalence pattern and distribution of 37 HPV-DNA types among urban Nigerian women. Methods: The study population ...

    • The Age-Specific Quantitative Effects of Metabolic Risk Factors on Cardiovascular Diseases and Diabetes: A Pooled Analysis 

      Singh, Gitanjali M.; Danaei, Goodarz; Farzadfar, Farshad; Stevens, Gretchen A.; Woodward, Mark; Wormser, David; Kaptoge, Stephen; Whitlock, Gary; Qiao, Qing; Lewington, Sarah; Di Angelantonio, Emanuele; vander Hoorn, Stephen; Lawes, Carlene M. M.; Ali, Mohammed K.; Mozaffarian, Dariush; Ezzati, Majid (Public Library of Science, 2013)
      Background: The effects of systolic blood pressure (SBP), serum total cholesterol (TC), fasting plasma glucose (FPG), and body mass index (BMI) on the risk of cardiovascular diseases (CVD) have been established in ...