Browsing SPH Scholarly Articles by Title

Now showing items 2350-2369 of 6362

    • Fetal Window of Vulnerability to Airborne Polycyclic Aromatic Hydrocarbons on Proportional Intrauterine Growth Restriction 

      Choi, Hyunok; Wang, Lu; Lin, Xihong; Spengler, John D.; Perera, Frederica P. (Public Library of Science, 2012)
      Background: Although the entire duration of fetal development is generally considered a highly susceptible period, it is of public health interest to determine a narrower window of heightened vulnerability to polycyclic ...

    • Fetuin-A and risk of coronary heart disease: a Mendelian randomization analysis and a pooled analysis of AHSG genetic variants in 7 prospective studies 

      Laugsand, Lars; Ix, Joachim; Bartz, Traci; Djousse, Luc; Kizer, Jorge; Tracy, Russell; Dehghan, Abbas; Rexrode, Kathryn; Lopez, Oscar; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Siscovick, David; O'Donnell, Christopher J.; Newman, Anne; Mukamal, Kenneth; Jensen, Majken (Elsevier, 2015)
      Background and aims: Fetuin-A has a plausible role in the inhibition of arterial calcification, but its association with risk of coronary heart disease (CHD) in the general population is unclear. We used two common genetic ...

    • Fetuin-A, Type 2 Diabetes, and Risk of Cardiovascular Disease in Older Adults: The Cardiovascular Health Study 

      Jensen, Majken K.; Bartz, Traci M.; Mukamal, Kenneth J.; Djoussé, Luc; Kizer, Jorge R.; Tracy, Russell P.; Zieman, Susan J.; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Siscovick, David S.; Shlipak, Michael; Ix, Joachim H. (American Diabetes Association, 2013)
      OBJECTIVE-Fetuin-A, a hepatic secretory protein that simultaneously inhibits arterial calcification and insulin action, is associated with type 2 diabetes, but its association with cardiovascular disease (CVD) is uncertain. ...

    • Few changes in food security and dietary intake from short-term participation in the Supplemental Nutrition Assistance Program among low-income Massachusetts adults 

      Leung, Cindy W.; Cluggish, Sarah; Villamor, Eduardo; Catalano, Paul J.; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600 (2014)
      Objective: To examine whether short-term participation in the Supplemental Nutrition Assistance Program (SNAP) affects food security and dietary quality among low-income adults recruited from a Massachusetts-wide emergency ...

    • FGFR3 expression in primary and metastatic urothelial carcinoma of the bladder 

      Guancial, Elizabeth A; Werner, Lillian; Bellmunt, Joaquim; Bamias, Aristotle; Choueiri, Toni K; Ross, Robert; Schutz, Fabio A; Park, Rachel S; O'Brien, Robert J; Hirsch, Michelle S; Barletta, Justine A; Berman, David M; Lis, Rosina; Loda, Massimo; Stack, Edward C; Garraway, Levi A; Riester, Markus; Michor, Franziska; Kantoff, Philip W; Rosenberg, Jonathan E (BlackWell Publishing Ltd, 2014)
      While fibroblast growth factor receptor 3 (FGFR3) is frequently mutated or overexpressed in nonmuscle-invasive urothelial carcinoma (UC), the prevalence of FGFR3 protein expression and mutation remains unknown in muscle-invasive ...

    • Fibroblast Growth Factor–23 and Cardiac Structure and Function 

      Agarwal, Isha; Ide, Noriko; Ix, Joachim H.; Kestenbaum, Bryan; Lanske, Beate; Schiller, Nelson B.; Whooley, Mary A.; Mukamal, Kenneth J. (Blackwell Publishing Ltd, 2014)
      Background: Fibroblast growth factor–23 (FGF‐23) is a phosphaturic factor previously associated with left ventricular hypertrophy and systolic dysfunction among individuals with chronic kidney disease. Whether FGF‐23 acts ...

    • Fibromyalgia is characterized by altered frontal and cerebellar structural covariance brain networks 

      Kim, Hyungjun; Kim, Jieun; Loggia, Marco L.; Cahalan, Christine; Garcia, Ronald G.; Vangel, Mark G.; Wasan, Ajay D.; Edwards, Robert R.; Napadow, Vitaly (Elsevier, 2015)
      Altered brain morphometry has been widely acknowledged in chronic pain, and recent studies have implicated altered network dynamics, as opposed to properties of individual brain regions, in supporting persistent pain. ...

    • Fibrosis-Related Biomarkers and Incident Cardiovascular Disease in Older Adults: The Cardiovascular Health Study 

      Agarwal, Isha; Glazer, Nicole; Barasch, Eddy; Biggs, Mary; Djousse, Luc; Fitzpatrick, Annette; Gottdiener, John; Ix, Joachim; Kizer, Jorge; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Sicovick, David; Tracy, Russell; Mukamal, Kenneth (2014)
      Background-Fibrotic changes in the heart and arteries have been implicated in a diverse range of cardiovascular diseases (CVD), but whether circulating biomarkers that reflect fibrosis are associated with CVD is unknown.Methods ...

    • Fibrosis-Related Biomarkers and Large and Small Vessel Disease: The Cardiovascular Health Study 

      Agarwal, Isha; Arnold, Alice; Glazer, Nicole; Barasch, Eddy; Djousse, Luc; Fitzpatrick, Annette; Gottdiener, John; Ix, Joachim; Jensen, Richard; Kizer, Jorge; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Sicovick, David; Tracy, Russell; Wong, Tien; Mukamal, Kenneth (Elsevier, 2015)
      Objective: Fibrosis has been implicated in a number of pathological, organ-based conditions of the liver, kidney, heart, and lungs. The objective of this study was to determine whether biomarkers of fibrosis are associated ...

    • Fibrosis-Related Biomarkers and Risk of Total and Cause-Specific Mortality: The Cardiovascular Health Study 

      Agarwal, Isha; Glazer, Nicole L.; Barasch, Eddy; Biggs, Mary L.; Djoussé, Luc; Fitzpatrick, Annette L.; Gottdiener, John S.; Ix, Joachim H.; Kizer, Jorge R.; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Siscovick, David S.; Tracy, Russell P.; Zieman, Susan J.; Mukamal, Kenneth J. (Oxford University Press, 2014)
      Fibrosis has been implicated in diverse diseases of the liver, kidney, lungs, and heart, but its importance as a risk factor for mortality remains unconfirmed. We determined the prospective associations of 2 complementary ...

    • Fifty-Year Fate and Impact of General Medical Journals 

      Ioannidis, John; Belbasis, Lazaros; Evangelou, Evangelos (Public Library of Science, 2010)
      Background: Influential medical journals shape medical science and practice and their prestige is usually appraised by citation impact metrics, such as the journal impact factor. However, how permanent are medical journals ...

    • The Financial Impact of the ‘Zero-Markup Policy for Essential Drugs’ on Patients in County Hospitals in Western Rural China 

      Zhou, Zhongliang; Su, Yanfang; Campbell, Benjamin; Zhou, Zhiying; Gao, Jianmin; Yu, Qiang; Chen, Jiuhao; Pan, Yishan (Public Library of Science, 2015)
      Objective: With a quasi-experimental design, this study aims to assess whether the Zero-markup Policy for Essential Drugs (ZPED) reduces the medical expense for patients at county hospitals, the major healthcare provider ...

    • Financial Incentives for Return of Service in Underserved Areas: a Systematic Review 

      Bärnighausen, Till; Bloom, David E. (BioMed Central, 2009)
      Background: In many geographic regions, both in developing and in developed countries, the number of health workers is insufficient to achieve population health goals. Financial incentives for return of service are intended ...

    • Financing Essential HIV Services: A New Economic Agenda 

      Vassall, Anna; Remme, Michelle; Watts, Charlotte; Hallett, Timothy; Siapka, Mariana; Vickerman, Peter; Terris-Prestholt, Fern; Haacker, Markus; Heise, Lori; Haines, Andy; Atun, Rifat; Piot, Peter (Public Library of Science, 2013)
      Anna Vassall and colleagues discuss the need for, and challenges facing, innovative and sustainable financing of the HIV response. Please see later in the article for the Editors' Summary

    • A finding of sex similarities rather than differences in COVID-19 outcomes 

      Shattuck-Heidorn, Heather; Danielsen, Ann Caroline; Gompers, Annika; Bruch, Joseph Dov; Zhao, Helen; Boulicault, Marion; Marsella, Jamie; Richardson, Sarah S. (Springer Science and Business Media LLC, 2021-09-22)
      The sex disparity in COVID-19 mortality varies widely and is of uncertain origin. In their recent Nature paper “Sex differences in immune responses that underlie COVID-19 disease outcomes," Takahashi et al. assess immune ...

    • Fine mapping and functional analysis of a common variant in MSMB on chromosome 10q11.2 associated with prostate cancer susceptibility 

      Lou, Hong; Yeager, Meredith; Li, Hongchuan; Bosquet, Jesus Gonzalez; Hayes, Richard B.; Orr, Nick; Yu, Kai; Hutchinson, Amy; Jacobs, Kevin B.; Kraft, Peter; Wacholder, Sholom; Chatterjee, Nilanjan; Feigelson, Heather Spencer; Thun, Michael J.; Diver, W. Ryan; Albanes, Demetrius; Virtamo, Jarmo; Weinstein, Stephanie; Ma, Jing; Gaziano, J. Michael; Stampfer, Meir; Schumacher, Fredrick R.; Giovannucci, Edward; Cancel-Tassin, Geraldine; Cussenot, Olivier; Valeri, Antoine; Andriole, Gerald L.; Crawford, E. David; Anderson, Stephen K.; Tucker, Margaret; Hoover, Robert N.; Fraumeni, Joseph F. Jr.; Thomas, Gilles; Hunter, David J.; Dean, Michael; Chanock, Stephen J. (National Academy of Sciences, 2009)
      Two recent genome-wide association studies have independently identified a prostate cancer susceptibility locus on chromosome 10q11.2. The most significant single-nucleotide polymorphism (SNP) marker reported, rs10993994, ...

    • Fine mapping of chromosome 15q25 implicates ZNF592 in neurosarcoidosis patients 

      Lareau, Caleb A; Adrianto, Indra; Levin, Albert M; Iannuzzi, Michael C; Rybicki, Benjamin A; Montgomery, Courtney G (John Wiley & Sons, Ltd, 2015)
      Neurosarcoidosis is a clinical subtype of sarcoidosis characterized by the presence of granulomas in the nervous system. Here, we report a highly significant association with a variant (rs75652600, P = 3.12 × 10−8, odds ...

    • Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2 

      Orr, Nick; Dudbridge, Frank; Dryden, Nicola; Maguire, Sarah; Novo, Daniela; Perrakis, Eleni; Johnson, Nichola; Ghoussaini, Maya; Hopper, John L.; Southey, Melissa C.; Apicella, Carmel; Stone, Jennifer; Schmidt, Marjanka K.; Broeks, Annegien; Van't Veer, Laura J.; Hogervorst, Frans B.; Fasching, Peter A.; Haeberle, Lothar; Ekici, Arif B.; Beckmann, Matthias W.; Gibson, Lorna; Aitken, Zoe; Warren, Helen; Sawyer, Elinor; Tomlinson, Ian; Kerin, Michael J.; Miller, Nicola; Burwinkel, Barbara; Marme, Frederik; Schneeweiss, Andreas; Sohn, Chistof; Guénel, Pascal; Truong, Thérèse; Cordina-Duverger, Emilie; Sanchez, Marie; Bojesen, Stig E.; Nordestgaard, Børge G.; Nielsen, Sune F.; Flyger, Henrik; Benitez, Javier; Zamora, Maria Pilar; Arias Perez, Jose Ignacio; Menéndez, Primitiva; Anton-Culver, Hoda; Neuhausen, Susan L.; Brenner, Hermann; Dieffenbach, Aida Karina; Arndt, Volker; Stegmaier, Christa; Hamann, Ute; Brauch, Hiltrud; Justenhoven, Christina; Brüning, Thomas; Ko, Yon-Dschun; Nevanlinna, Heli; Aittomäki, Kristiina; Blomqvist, Carl; Khan, Sofia; Bogdanova, Natalia; Dörk, Thilo; Lindblom, Annika; Margolin, Sara; Mannermaa, Arto; Kataja, Vesa; Kosma, Veli-Matti; Hartikainen, Jaana M.; Chenevix-Trench, Georgia; Beesley, Jonathan; Lambrechts, Diether; Moisse, Matthieu; Floris, Guiseppe; Beuselinck, Benoit; Chang-Claude, Jenny; Rudolph, Anja; Seibold, Petra; Flesch-Janys, Dieter; Radice, Paolo; Peterlongo, Paolo; Peissel, Bernard; Pensotti, Valeria; Couch, Fergus J.; Olson, Janet E.; Slettedahl, Seth; Vachon, Celine; Giles, Graham G.; Milne, Roger L.; McLean, Catriona; Haiman, Christopher A.; Henderson, Brian E.; Schumacher, Fredrick; Le Marchand, Loic; Simard, Jacques; Goldberg, Mark S.; Labrèche, France; Dumont, Martine; Kristensen, Vessela; Alnæs, Grethe Grenaker; Nord, Silje; Borresen-Dale, Anne-Lise; Zheng, Wei; Deming-Halverson, Sandra; Shrubsole, Martha; Long, Jirong; Winqvist, Robert; Pylkäs, Katri; Jukkola-Vuorinen, Arja; Grip, Mervi; Andrulis, Irene L.; Knight, Julia A.; Glendon, Gord; Tchatchou, Sandrine; Devilee, Peter; Tollenaar, Robertus A. E. M.; Seynaeve, Caroline M.; Van Asperen, Christi J.; Garcia-Closas, Montserrat; Figueroa, Jonine; Chanock, Stephen J.; Lissowska, Jolanta; Czene, Kamila; Darabi, Hatef; Eriksson, Mikael; Klevebring, Daniel; Hooning, Maartje J.; Hollestelle, Antoinette; van Deurzen, Carolien H. M.; Kriege, Mieke; Hall, Per; Li, Jingmei; Liu, Jianjun; Humphreys, Keith; Cox, Angela; Cross, Simon S.; Reed, Malcolm W. R.; Pharoah, Paul D. P.; Dunning, Alison M.; Shah, Mitul; Perkins, Barbara J.; Jakubowska, Anna; Lubinski, Jan; Jaworska-Bieniek, Katarzyna; Durda, Katarzyna; Ashworth, Alan; Swerdlow, Anthony; Jones, Michael; Schoemaker, Minouk J.; Meindl, Alfons; Schmutzler, Rita K.; Olswold, Curtis; Slager, Susan; Toland, Amanda E.; Yannoukakos, Drakoulis; Muir, Kenneth; Lophatananon, Artitaya; Stewart-Brown, Sarah; Siriwanarangsan, Pornthep; Matsuo, Keitaro; Ito, Hidema; Iwata, Hiroji; Ishiguro, Junko; Wu, Anna H.; Tseng, Chiu-chen; Van Den Berg, David; Stram, Daniel O.; Teo, Soo Hwang; Yip, Cheng Har; Kang, Peter; Ikram, Mohammad Kamran; Shu, Xiao-Ou; Lu, Wei; Gao, Yu-Tang; Cai, Hui; Kang, Daehee; Choi, Ji-Yeob; Park, Sue K.; Noh, Dong-Young; Hartman, Mikael; Miao, Hui; Lim, Wei Yen; Lee, Soo Chin; Sangrajrang, Suleeporn; Gaborieau, Valerie; Brennan, Paul; Mckay, James; Wu, Pei-Ei; Hou, Ming-Feng; Yu, Jyh-Cherng; Shen, Chen-Yang; Blot, William; Cai, Qiuyin; Signorello, Lisa B.; Luccarini, Craig; Bayes, Caroline; Ahmed, Shahana; Maranian, Mel; Healey, Catherine S.; González-Neira, Anna; Pita, Guillermo; Alonso, M. Rosario; Álvarez, Nuria; Herrero, Daniel; Tessier, Daniel C.; Vincent, Daniel; Bacot, Francois; Hunter, David J.; Lindstrom, Sara; Dennis, Joe; Michailidou, Kyriaki; Bolla, Manjeet K.; Easton, Douglas F.; dos Santos Silva, Isabel; Fletcher, Olivia; Peto, Julian (Oxford University Press, 2015)
      We recently identified a novel susceptibility variant, rs865686, for estrogen-receptor positive breast cancer at 9q31.2. Here, we report a fine-mapping analysis of the 9q31.2 susceptibility locus using 43 160 cases and 42 ...

    • Fine-Mapping the HOXB Region Detects Common Variants Tagging a Rare Coding Allele: Evidence for Synthetic Association in Prostate Cancer 

      Saunders, Edward J.; Dadaev, Tokhir; Leongamornlert, Daniel A.; Jugurnauth-Little, Sarah; Tymrakiewicz, Malgorzata; Wiklund, Fredrik; Al Olama, Ali Amin; Benlloch, Sara; Neal, David E.; Hamdy, Freddie C.; Donovan, Jenny L.; Giles, Graham G.; Severi, Gianluca; Gronberg, Henrik; Aly, Markus; Haiman, Christopher A.; Schumacher, Fredrick; Henderson, Brian E.; Lindstrom, Sara; Kraft, Peter; Hunter, David J.; Gapstur, Susan; Chanock, Stephen; Berndt, Sonja I.; Albanes, Demetrius; Andriole, Gerald; Schleutker, Johanna; Weischer, Maren; Nordestgaard, Børge G.; Canzian, Federico; Campa, Daniele; Riboli, Elio; Key, Tim J.; Travis, Ruth C.; Ingles, Sue A.; John, Esther M.; Hayes, Richard B.; Pharoah, Paul; Khaw, Kay-Tee; Stanford, Janet L.; Ostrander, Elaine A.; Signorello, Lisa B.; Thibodeau, Stephen N.; Schaid, Daniel; Maier, Christiane; Kibel, Adam S.; Cybulski, Cezary; Cannon-Albright, Lisa; Brenner, Hermann; Park, Jong Y.; Kaneva, Radka; Batra, Jyotsna; Clements, Judith A.; Teixeira, Manuel R.; Xu, Jianfeng; Mikropoulos, Christos; Goh, Chee; Govindasami, Koveela; Guy, Michelle; Wilkinson, Rosemary A.; Sawyer, Emma J.; Morgan, Angela; Easton, Douglas F.; Muir, Ken; Eeles, Rosalind A.; Kote-Jarai, Zsofia (Public Library of Science, 2014)
      The HOXB13 gene has been implicated in prostate cancer (PrCa) susceptibility. We performed a high resolution fine-mapping analysis to comprehensively evaluate the association between common genetic variation across the ...

    • Fine-tuning of macrophage activation using synthetic rocaglate derivatives 

      Bhattacharya, Bidisha; Chatterjee, Sujoy; Devine, William G.; Kobzik, Lester; Beeler, Aaron B.; Porco, John A.; Kramnik, Igor (Nature Publishing Group, 2016)
      Drug-resistant bacteria represent a significant global threat. Given the dearth of new antibiotics, host-directed therapies (HDTs) are especially desirable. As IFN-gamma (IFNγ) plays a central role in host resistance to ...