Browsing SPH Scholarly Articles by Title

Now showing items 25-44 of 6362

    • A genetic variant at the fatty acid-binding protein aP2 locus reduces the risk for hypertriglyceridemia, type 2 diabetes, and cardiovascular disease 

      Tuncman, G.; Erbay, E.; Hom, X.; Vivo, I. De; Campos, H.; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; Hotamisligil, G. S. (National Academy of Sciences, 2006)
      Obesity and the associated pathologies including dyslipidemia, insulin resistance, type 2 diabetes, and cardiovascular disease constitute a major threat to global human health. Yet, the genetic factors that differentially ...

    • A genome-wide analysis of gene–caffeine consumption interaction on basal cell carcinoma 

      Li, Xin; Cornelis, Marilyn; Liang, Liming; Song, Fengju; De Vivo, Immaculata; Giovannucci, Edward; Tang, Jean; Han, Jiali (Oxford University Press, 2016)
      Animal models have suggested that oral or topical administration of caffeine could inhibit ultraviolet-induced carcinogenesis via the ataxia telangiectasia and rad3 (ATR)-related apoptosis. Previous epidemiological studies ...

    • A genome-wide investigation of food addiction 

      Cornelis, Marilyn; Flint, Alan; Field, Alison; Kraft, Peter; Han, Jiali; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600; van Dam, Rob M. (Wiley, 2016)
      Objective: Evidence of parallels between drug addiction and eating behavior continues to accumulate. Genetic studies of addictive substances have yielded a number of susceptibility loci that point to common higher order ...

    • A Genome-wide Pleiotropy Scan for Prostate Cancer Risk 

      Panagiotou, Orestis; Travis, Ruth; Campa, Daniele; Berndt, Sonja; Lindstrom, Sara; Kraft, Peter; Schumacher, Fredrick; Siddiq, Afshan; Papatheodorou, Stefania; Stanford, Janet; Albanes, Demetrius; Virtamo, Jarmo; Weinstein, Stephanie; Diver, W. Ryan; Gapstur, Susan; Stevens, Victoria; Boeing, Heiner; Bueno-de-Mesquita, H. Bas; Gurrea, Aurelio Barricarte; Kaaks, Rudolf; Khaw, Kay-Tee; Krogh, Vittorio; Overvad, Kim; Riboli, Elio; Trichopoulos, Dimitrios; Giovannucci, Edward; Stampfer, Meir; Haiman, Christopher; Henderson, Brian; Le Marchand, Loic; Gaziano, J. Michael; DavidJ. Hunter; Koutros, Stella; Yeager, Meredith; Hoover, Robert; Chanock, Stephen; Wacholder, Sholom; Key, Timothy; Tsilidis, Konstantinos; PRACTICAL Consortium (Elsevier, 2015)
      Background: No single-nucleotide polymorphisms (SNPs) specific for aggressive prostate cancer have been identified in genome-wide association studies (GWAS). Objective: To test if SNPs associated with other traits may also ...

    • A Genome-Wide Screen for Interactions Reveals a New Locus on 4p15 Modifying the Effect of Waist-to-Hip Ratio on Total Cholesterol 

      Surakka, Ida; Isaacs, Aaron; Karssen, Lennart; Laurila, Pirkka-Pekka; Middelberg, Rita; Tikkanen, Emmi; Ried, Janina; Lamina, Claudia; Mangino, Massimo; Igl, Wilmar; Hottenga, Jouke-Jan; Lagou, Vasiliki; van der Harst, Pim; Leach, Irene Mateo; Tõnu Esko; Zoltán Kutalik; Wainwright, Nicholas; Struchalin, Maksim; Sarin, Antti-Pekka; Kangas, Antti; Viikari, Jorma; Perola, Markus; Rantanen, Taina; Petersen, Ann-Kristin; Soininen, Pasi; Åsa Johansson; Soranzo, Nicole; Heath, Andrew; Papamarkou, Theodore; Prokopenko, Inga; Tönjes, Anke; Kronenberg, Florian; Döring, Angela; Rivadeneira, Fernando; Montgomery, Grant; Whitfield, John; Kähönen, Mika; Lehtimäki, Terho; Freimer, Nelson; Willemsen, Gonneke; de Geus, Eco J. C.; Palotie, Aarno; Sandhu, Manj; Waterworth, Dawn; Metspalu, Andres; Stumvoll, Michael; Uitterlinden, André G.; Jula, Antti; Navis, Gerjan; Wijmenga, Cisca; Wolffenbuttel, Bruce; Taskinen, Marja-Riitta; Ala-Korpela, Mika; Kaprio, Jaakko; Kyvik, Kirsten; Boomsma, Dorret; Pedersen, Nancy; Gyllensten, Ulf; Wilson, James; Rudan, Igor; Campbell, Harry; Pramstaller, Peter; Spector, Tim; Witteman, Jacqueline; Eriksson, Johan; Salomaa, Veikko; Oostra, Ben; Raitakari, Olli; Wichmann, H.-Erich; Gieger, Christian; Marjo-Riitta Järvelin; Martin, Nicholas; Hofman, Albert; McCarthy, Mark; Peltonen, Leena; van Duijn, Cornelia M.; Aulchenko, Yurii; Ripatti, Samuli (Public Library of Science, 2011)

    • A glossary for health inequalities 

      Kawachi, I.; Subramanian, S.; Almeida-Filho, N. (BMJ Publishing Group, 2002)
      In this glossary, the authors address eight key questions pertinent to health inequalities: (1) What is the distinction between health inequality and health inequity?; (2) Should we assess health inequalities themselves, ...

    • A high anthocyanin intake is associated with a reduced risk of myocardial infarction in young and middle-aged women 

      Cassidy, Aedín; Mukamal, Kenneth J.; Liu, Lydia; Franz, Mary; Eliassen, A. Heather; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600 (American Heart Association, 2013)
      Background-Our current knowledge of modifiable risk factors to prevent myocardial infarction (MI) in young and middle-aged women is limited, and the impact of diet is largely unknown. Dietary flavonoids exert potential ...

    • A large cohort study of nonsteroidal anti-inflammatory drugs and renal cell carcinoma incidence in the National Institutes of Health–AARP Diet and Health Study 

      Liu, Wei; Park, Yikyung; Purdue, Mark; Giovannucci, Edward; Cho, Eunyoung (Springer (part of Springer Nature), 2013)
      Existing epidemiologic evidence for the association between nonsteroidal anti-inflammatory drugs (NSAIDs) and renal cell carcinoma (RCC) risk is inconsistent.We investigated the association between the use of aspirin and ...

    • A large prospective study of SEP15 genetic variation, interaction with plasma selenium levels, and prostate cancer risk and survival 

      Penney, Kathryn L.; Schumacher, Fredrick R.; Li, Haojie; Kraft, Peter; Morris, J. Steven; Kurth, Tobias; Mucci, Lorelei A.; Hunter, David J.; Kantoff, Philip W.; Stampfer, Meir; Ma, Jing (American Association for Cancer Research, 2010)
      The role of selenium in prostate cancer (PCa) risk remains controversial, but many epidemiologic studies suggest an inverse association with more aggressive disease. A recently discovered selenoprotein, SEP15, which is ...

    • A Large Study of Androgen Receptor Germline Variants and Their Relation to Sex Hormone Levels and Prostate Cancer Risk. Results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium 

      Lindström, Sara; Ma, Jing; Altshuler, David; Giovannucci, Edward; Riboli, Elio; Albanes, Demetrius; Allen, Naomi E.; Berndt, Sonja I.; Boeing, Heiner; Bueno-de-Mesquita, H. Bas; Chanock, Stephen J.; Dunning, Alison M.; Feigelson, Heather Spencer; Gaziano, J. Michael; Haiman, Christopher A.; Hayes, Richard B.; Henderson, Brian E.; Hunter, David J.; Kaaks, Rudolf; Kolonel, Laurence N.; Marchand, Loic Le; Martínez, Carmen; Overvad, Kim; Siddiq, Afshan; Stampfer, Meir; Stattin, Pär; Stram, Daniel O.; Thun, Michael J.; Trichopoulos, Dimitrios; Tumino, Rosario; Virtamo, Jarmo; Weinstein, Stephanie J.; Yeager, Meredith; Kraft, Peter; Freedman, Matthew L. (Oxford University Press, 2010)
      Background: Androgens are key regulators of prostate gland maintenance and prostate cancer growth, and androgen deprivation therapy has been the mainstay of treatment for advanced prostate cancer for many years. Along-standing ...

    • A long-term survival analysis of prediagnostic body mass index, plasma C-peptide concentration, and prostate cancer-specific mortality among men with prostate cancer 

      Ma, Jing; Li, Haojie; Giovannucci, Ed; Mucci, Lorelei; Qiu, Weiliang; Nguyen, Paul L.; Gaziano, J. Michael; Pollak, Michael; Stampfer, Meir (Elsevier, 2008)

    • A mathematical framework to determine the temporal sequence of somatic genetic events in cancer 

      Attolini, Camille Stephan-Otto; Cheng, Yu-Kang; Beroukhim, Rameen; Getz, Gad; Abdel-Wahab, Omar; Levine, Ross L.; Mellinghoff, Ingo K.; Michor, Franziska (National Academy of Sciences, 2010)
      Human cancer is caused by the accumulation of genetic alterations in cells. Of special importance are changes that occur early during malignant transformation because they may result in oncogene addiction and represent ...

    • A meta-analysis of cholecystectomy and risk of colorectal cancer 

      Giovannucci, Edward; Colditz, Graham A.; Stampfer, Meir (Elsevier, 1993)

    • A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease 

      Olama, Ali Amin Al; Kote-Jarai, Zsofia; Schumacher, Fredrick; Wiklund, Fredrik; Berndt, Sonja; Benlloch, Sara; Giles, Graham; Severi, Gianluca; Neal, David; Hamdy, Freddie; Donovan, Jenny; Hunter, David; Henderson, Brian; Thun, Michael; Gaziano, Michael; Giovannucci, Edward; Siddiq, Afshan; Travis, Ruth; Cox, David; Canzian, Federico; Riboli, Elio; Key, Timothy; Andriole, Gerald; Albanes, Demetrius; Hayes, Richard; Schleutker, Johanna; Auvinen, Anssi; Tammela, Teuvo L. J.; Weischer, Maren; Stanford, Janet; Ostrander, Elaine; Cybulski, Cezary; Lubinski, Jan; Thibodeau, Stephen; Schaid, Daniel; Sorensen, Karina; Batra, Jyotsna; Clements, Judith; Chambers, Suzanne; Aitken, Joanne; Gardiner, Robert; Maier, Christiane; Vogel, Walther; Dörk, Thilo; Brenner, Hermann; Habuchi, Tomonori; Ingles, Sue; John, Esther; Dickinson, Joanne; Cannon-Albright, Lisa; Teixeira, Manuel; Kaneva, Radka; Zhang, Hong-Wei; Lu, Yong-Jie; Park, Jong; Cooney, Kathleen; Muir, Kenneth; Leongamornlert, Daniel; Saunders, Edward; Tymrakiewicz, Malgorzata; Mahmud, Nadiya; Guy, Michelle; Govindasami, Koveela; O'Brien, Lynne T.; Wilkinson, Rosemary; Hall, Amanda; Sawyer, Emma; Dadaev, Tokhir; Morrison, Jonathan; Dearnaley, David; Horwich, Alan; Huddart, Robert; Khoo, Vincent; Parker, Christopher; Van As, Nicholas; Woodhouse, Christopher; Thompson, Alan; Dudderidge, Tim; Ogden, Chris; Cooper, Colin; Lophatonanon, Artitaya; Southey, Melissa; Hopper, John; English, Dallas; Virtamo, Jarmo; Le Marchand, Loic; Campa, Daniele; Kaaks, Rudolf; Lindstrom, Sara; Diver, W. Ryan; Gapstur, Susan; Yeager, Meredith; Cox, Angela; Stern, Mariana; Corral, Roman; Aly, Markus; Isaacs, William; Adolfsson, Jan; Xu, Jianfeng; Zheng, S. Lilly (Oxford University Press, 2013)
      Genome-wide association studies (GWAS) have identified multiple common genetic variants associated with an increased risk of prostate cancer (PrCa), but these explain less than one-third of the heritability. To identify ...

    • A meta-analysis of individual participant data reveals an association between circulating levels of IGF-I and prostate cancer risk 

      Travis, Ruth; Appleby, Paul; Martin, Richard; Holly, Jeff M. P.; Albanes, Demetrius; Black, Amanda; Bueno-de-Mesquita, H. B.; Chan, June; Chen, Chu; Chirlaque, Maria-Dolores; Cook, Michael; Deschasaux, Mélanie; Donovan, Jenny; Ferrucci, Luigi; Galan, Pilar; Giles, Graham; Giovannucci, Edward; Gunter, Marc; Habel, Laurel; Hamdy, Freddie; Helzlsouer, Kathy; Hercberg, Serge; Hoover, Robert; Janssen, Joseph A. M. J. L.; Kaaks, Rudolf; Kubo, Tatsuhiko; Le Marchand, Loic; Metter, E. Jeffrey; Mikami, Kazuya; Morris, Joan; Neal, David; Neuhouser, Marian; Ozasa, Kotaro; Palli, Domenico; Platz, Elizabeth; Pollak, Michael; Price, Alison; Roobol, Monique; Schaefer, Catherine; Schenk, Jeannette; Severi, Gianluca; Stampfer, Meir; Pär Stattin; Tamakoshi, Akiko; Tangen, Catherine; Touvier, Mathilde; Wald, Nicholas; Weiss, Noel; Ziegler, Regina; Key, Timothy; Allen, Naomi (American Association for Cancer Research, 2016)
      The role of insulin-like growth factors (IGF) in prostate cancer development is not fully understood. To investigate the association between circulating concentrations of IGFs (IGF-I, IGF-II, IGFBP-1, IGFBP-2, and IGFBP-3) ...

    • A Meta-Analysis Shows That Docosahexaenoic Acid from Algal Oil Reduces Serum Triglycerides and Increases HDL-Cholesterol and LDL-Cholesterol in Persons without Coronary Heart Disease 

      Bernstein, A. M.; Ding, E. L.; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Rimm, Eric Bruce::0ab2926c8242f35e5a982e3cf59f4987::600 (Oxford University Press, 2012)
      Certain algae contain the (n-3) fatty acid DHA, yet the relation between algal oil supplementation and cardiovascular disease risk factors has not been systematically examined. Our objective was to examine the relation ...

    • A Multilevel Analysis of Key Forms of Community- and Individual-Level Social Capital as Predictors of Self-Rated Health in the United States 

      Kim, Daniel; Kawachi, Ichiro (Springer Verlag, 2006)
      Communities may be rich or poor in a variety of stocks of social capital. Studies that have investigated relations among these forms and their simultaneous and combined health effects are sparse. Using data on a sample of ...

    • A Multilevel Analysis of Social Ties and Social Cohesion among Latinos and Their Neighborhoods: Results from Chicago 

      Almeida, Joanna; Kawachi, Ichiro; Molnar, Beth E.; Subramanian, S. V. (Springer Verlag, 2009)
      Research suggests that, among Latinos, there are health benefits associated with living in a neighborhood populated with coethnics. While social networks and social cohesion are the proposed explanation for the salubrious ...

    • A Nested Case-Control Study of Plasma 25-Hydroxyvitamin D Concentrations and Risk of Colorectal Cancer 

      Wu, K.; Feskanich, D.; Fuchs, C. S.; Willett, Walter C.::94559ea206eef8a8844fc5b80654fa5b::600; Hollis, B. W.; Giovannucci, E. L. (Oxford University Press, 2007)
      Background: Low vitamin D status has long been implicated in colorectal carcinogenesis. We investigated this relationship in a nested case-control study within the Health Professionals Follow-up Study (HPFS), a large ongoing ...

    • A novel fatty acid lipophilic index and risk of CHD in US men: the Health Professionals Follow-Up Study 

      Wu, Hongyu; Ding, Eric L.; Toledo, Estefanía T.; Campos, Hannia; Baylin, Ana; Hu, Frank B.; Sun, Qi (Cambridge University Press, 2013)
      Few epidemiological studies have examined the association between an overall fatty acid (FA) profile and CHD risk. The aim of the present study was to examine a novel index that summarises individual FA levels based on FA ...