Browsing SPH Scholarly Articles by Title
Now showing items 2796-2815 of 6362
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Hallux valgus and plantar pressure loading: the Framingham foot study
(BioMed Central, 2013)Background: Hallux valgus (HV), a common structural foot deformity, can cause foot pain and lead to limited mobility. The purpose of this study was to evaluate differences in plantar pressure and force during gait by HV ... -
Halo effect of a weight-loss trial on spouses: the DIRECT-Spouse study
(Cambridge University Press, 2010)Objective: We examined the halo effect of a 2-year weight-loss diet trial, the Dietary Intervention Randomized Controlled Trial (DIRECT), on the weight and nutritional patterns of participants' spouses. Design: DIRECT ... -
Handling random errors and biases in methods used for short-term dietary assessment
(Faculdade de Saúde Pública da Universidade de São Paulo, 2014)Epidemiological studies have shown the effect of diet on the incidence of chronic diseases; however, proper planning, designing, and statistical modeling are necessary to obtain precise and accurate food consumption data. ... -
Handling the data management needs of high-throughput sequencing data: SpeedGene, a compression algorithm for the efficient storage of genetic data
(BioMed Central, 2012)Background: As Next-Generation Sequencing data becomes available, existing hardware environments do not provide sufficient storage space and computational power to store and process the data due to their enormous size. ... -
Haploinsufficiency of Hedgehog interacting protein causes increased emphysema induced by cigarette smoke through network rewiring
(BioMed Central, 2015)Background: The HHIP gene, encoding Hedgehog interacting protein, has been implicated in chronic obstructive pulmonary disease (COPD) by genome-wide association studies (GWAS), and our subsequent studies identified a ... -
Haplotype Block Partitioning and Tag SNP Selection Using Genotype Data and Their Applications to Association Studies
(Cold Spring Harbor Laboratory Press, 2004)Recent studies have revealed that linkage disequilibrium (LD) patterns vary across the human genome with some regions of high LD interspersed by regions of low LD. A small fraction of SNPs (tag SNPs) is sufficient to capture ... -
Haplotype Information and Linkage Disequilibrium Mapping for Single Nucleotide Polymorphisms
(Cold Spring Harbor Laboratory Press, 2003)Single nucleotide polymorphisms in the human genome have become an increasingly popular topic in that their analyses promise to be a key step toward personalized medicine. We investigate two related questions, how much the ... -
Haptoglobin Genotype Is a Consistent Marker of Coronary Heart Disease Risk Among Individuals with Elevated Glycosylated Hemoglobin
(Elsevier, 2013)Objectives This study sought to investigate into the biologically plausible interaction between the common haptoglobin (Hp) polymorphism rs#72294371 and glycosylated hemoglobin (HbA(1c)) on risk of coronary heart disease ... -
Harnessing Poverty Alleviation to Reduce the Stigma of HIV in Sub-Saharan Africa
(Public Library of Science, 2013)Alexander Tsai and colleagues highlight the complex relationship between poverty and HIV stigma in sub-Saharan Africa, and discuss possible ways to break the cycle. Please see later in the article for the Editors' Summary -
Harnessing the diversity of small-scale actors is key to the future of aquatic food systems
(Springer Science and Business Media LLC, 2021-09-15) -
Harnessing the Medicaid Analytic eXtract (MAX) to Evaluate Medications in Pregnancy: Design Considerations
(Public Library of Science, 2013)Background: In the absence of clinical trial data, large post-marketing observational studies are essential to evaluate the safety and effectiveness of medications during pregnancy. We identified a cohort of pregnancies ... -
Has the tobacco industry evaded the FDA's ban on ‘Light’ cigarette descriptors?
(BMJ Publishing Group, 2014)Background: Under the Family Smoking Prevention and Tobacco Control Act (FSPTCA), the Food and Drug Administration (FDA) banned the use of “Lights” descriptors or similar terms on tobacco products that convey messages of ... -
Has the Tobacco Industry Evaded the Intent and Purpose of the FDA's Ban on "Light" Cigarette Descriptors
(BMJ Journals, 2013)Background Under the Family Smoking Prevention and Tobacco Control Act (FSPTCA), the Food and Drug Administration (FDA) banned the use of “Lights” descriptors or similar terms on tobacco products that convey messages of ... -
A hazardous substance exposure prevention rating method for intervention needs assessment and effectiveness evaluation: the Small Business Exposure Index
(BioMed Central, 2009)Aims: This paper describes the refinement and adaptation to small business of a previously developed method for systematically prioritizing needs for intervention on hazardous substance exposures in manufacturing worksites, ... -
HbA1c measured in stored erythrocytes and mortality rate among middle-aged and older women
(Springer Verlag, 2008)Aims/hypothesis Diabetes is known to increase mortality rate, but the degree to which mild hyperglycaemia may be associated with the risk of death is uncertain. We examined the association between HbA(1c) measured in stored ... -
HCV-Related Burden of Disease in Europe: A Systematic Assessment of Incidence, Prevalence, Morbidity, and Mortality
(BioMed Central, 2009)Background: Hepatitis C virus (HCV) is a leading cause of chronic liver disease, end-stage cirrhosis, and liver cancer, but little is known about the burden of disease caused by the virus. We summarised burden of disease ... -
HDAC6 Inhibitors Modulate Lys49 Acetylation and Membrane Localization of β-Catenin in Human iPSC-Derived Neuronal Cells
(American Chemical Society, 2014)We examined the effects of isoform-specific histone deacetylase (HDAC) inhibitors on β-catenin posttranslational modifications in neural progenitor cells (NPCs) derived from human induced pluripotent stem cells (iPSCs). ... -
Headache, migraine and risk of brain tumors in women: prospective cohort study
(Springer Milan, 2015)Background: While headache is a common symptom among brain tumors patients, often patients with common headache have concerns of being at risk for developing brain tumors. We aimed to disprove that migraine or headache in ... -
Headache, migraine, and structural brain lesions and function: population based Epidemiology of Vascular Ageing-MRI study
(BMJ Publishing Group Ltd., 2011)Objective: To evaluate the association of overall and specific headaches with volume of white matter hyperintensities, brain infarcts, and cognition. Design: Population based, cross sectional study. Setting: Epidemiology ... -
Health and Economic Burden of Post-Partum Staphylococcus aureus Breast Abscess
(Public Library of Science, 2013)Objectives: To determine the health and economic burdens of post-partum Staphylococcus aureus breast abscess. Study design We conducted a matched cohort study (N = 216) in a population of pregnant women (N = 32,770) who ...