Now showing items 774-793 of 6362

    • Biological variability dominates and influences analytical variance in HPLC-ECD studies of the human plasma metabolome 

      Shurubor, Yevgeniya I; Matson, Wayne R; Willett, Walter C.; Hankinson, Susan Elizabeth; Kristal, Bruce S. (BioMed Central, 2007)
      Background: Biomarker-based assessments of biological samples are widespread in clinical, pre-clinical, and epidemiological investigations. We previously developed serum metabolomic profiles assessed by HPLC-separations ...
    • Biological, psychological and social processes that explain celebrities’ influence on patients’ health-related behaviors 

      Hoffman, Steven J; Tan, Charlie (BioMed Central, 2015)
      Background: Celebrities can have substantial influence as medical advisors. However, their impact on public health is equivocal: depending on the advice’s validity and applicability, celebrity engagements can benefit or ...
    • Biomarker Validation of Dietary Intervention in Two Multiethnic Populations 

      Eliassen, A Heather; Colditz, Graham A.; Peterson, Karen E.; Furtado, Jeremy Daniel; Fay, Martha Elizabeth; Sorensen, Glorian; Emmons, Karen Maria (Centers for Disease Control and Prevention, 2006)
      Introduction: Intervention studies have been designed to change dietary and lifestyle factors associated with chronic diseases, but self-reported behavior change may incorporate intervention-related bias. This study examines ...
    • Biomarker-Defined Subsets of Common Diseases: Policy and Economic Implications of Orphan Drug Act Coverage 

      Kesselheim, Aaron S.; Treasure, Carolyn L.; Joffe, Steven (Public Library of Science, 2017)
      Aaron Kesselheim and colleagues examine orphan-designated drugs approved between 2009 and 2015 in the United States.
    • Biomarkers in environmental toxicology: state of the art. 

      Grandjean, Philippe; Brown, SS; Reavey, P; Young, DS (American Association for Clinical Chemistry, 1995)
    • Biomarkers in epidemiology 

      Grandjean, Philippe (American Association for Clinical Chemistry, 1995)
    • Biomarkers of chemical exposure: state of the art. 

      Grandjean, Philippe; Brown, SS; Reavey, P; Young, DS (American Association for Clinical Chemistry, 1994)
      Establishing associations between environmental agents and disease presents challenges to both epidemiologists and toxicologists, particularly in cases of complex gene-environment interactions and when there is a long ...
    • Biomarkers of Dairy Fatty Acids and Risk of Cardiovascular Disease in the Multi‐Ethnic Study of Atherosclerosis 

      de Oliveira Otto, Marcia C.; Nettleton, Jennifer A.; Lemaitre, Rozenn N.; M. Steffen, Lyn; Kromhout, Daan; Rich, Stephen S.; Y. Tsai, Michael; Jacobs, David R.; Mozaffarian, Dariush (Blackwell Publishing Ltd, 2013)
      Background: Evidence regarding the role of dairy fat intake in cardiovascular disease (CVD) has been mixed and inconclusive. Most earlier studies have used self‐reported measures of dietary intake and focused on relatively ...
    • Biomarkers of Environmental Enteropathy are Positively Associated with Immune Responses to an Oral Cholera Vaccine in Bangladeshi Children 

      Uddin, Muhammad Ikhtear; Islam, Shahidul; Nishat, Naoshin S.; Hossain, Motaher; Rafique, Tanzeem Ahmed; Rashu, Rasheduzzaman; Hoq, Mohammad Rubel; Zhang, Yue; Saha, Amit; Harris, Jason B.; Calderwood, Stephen B.; Bhuiyan, Taufiqur Rahman; Ryan, Edward T.; Leung, Daniel T.; Qadri, Firdausi (Public Library of Science, 2016)
      Environmental enteropathy (EE) is a poorly understood condition that refers to chronic alterations in intestinal permeability, absorption, and inflammation, which mainly affects young children in resource-limited settings. ...
    • Biomarkers of Lead Exposure and DNA Methylation within Retrotransposons 

      Bollati, Valentina; Tarantini, Letizia; Hu, Howard; Schwartz, Joel David; Wright, Rosalind Jo; Park, Sung Kyun; Sparrow, David; Vokonas, Pantel S; Baccarelli, Andrea; Wright, Robert O. (National Institute of Environmental Health Sciences, 2010)
      Background: DNA methylation is an epigenetic mark that regulates gene expression. Changes in DNA methylation within white blood cells may result from cumulative exposure to environmental metals such as lead. Bone lead, a ...
    • Biomedical Ph.D. Students Enrolled in Two Elite Universities in the United Kingdom and the United States Report Adopting Multiple Learning Relationships 

      Kemp, Matthew W.; Lazarus, Benjamin M.; Perron, Gabriel G.; Hanage, William P.; Chapman, Elaine (Public Library of Science, 2014)
      Objective: The ability to form multiple learning relationships is a key element of the doctoral learning environment in the biomedical sciences. Of these relationships, that between student and supervisor has long been ...
    • Biomedical publications on Ebola and the 2014 outbreak 

      Ballabeni, Andrea; Boggio, Andrea (F1000Research, 2015)
      In this research note we examine the biomedical publication output about Ebola in 2014. We show that the volume of publications has dramatically increased in the past year. The rise reflects an impressive growth starting ...
    • Bipartite Community Structure of eQTLs 

      Platig, John; Castaldi, Peter J.; DeMeo, Dawn; Quackenbush, John (Public Library of Science, 2016)
      Genome Wide Association Studies (GWAS) and expression quantitative trait locus (eQTL) analyses have identified genetic associations with a wide range of human phenotypes. However, many of these variants have weak effects ...
    • Birth cohorts in asthma and allergic diseases: Report of a NIAID/NHLBI/MeDALL joint workshop 

      Bousquet, Jean; Gern, James E.; Martinez, Fernando D.; Anto, Josep M.; Johnson, Christine Haynes; Holt, Patrick G.; Lemanske, Robert F.; Le Souëf, Peter N.; Tepper, Robert Ira; von Mutius, Erika R.M.; Arshad, S. Hasan; Bacharier, Leonard B.; Becker, Allan; Belanger, Kathleen; Bergström, Anna; Bernstein, David I.; Cabana, Michael D.; Carroll, Kecia N.; Castro, Mario; Cooper, Philip J.; Gillman, Matthew William; Gold, Diane R.; Henderson, John; Heinrich, Joachim; Hong, Soo-Jong; Jackson, Danielle; Keil, Thomas; Kozyrskyj, Anita L.; Lødrup Carlsen, Karin C.; Miller, Rachel Blair; Momas, Isabelle; Morgan, Wayne J.; Noel, Patricia; Ownby, Dennis R.; Pinart, Mariona; Ryan, Patrick H.; Schwaninger, Julie M.; Sears, Malcolm R.; Simpson, Angela; Smit, Henriette A.; Stern, Debra A.; Subbarao, Padmaja; Valenta, Rudolf; Wang, Xiaobin; Weiss, Scott Tillman; Wood, Robert J.; Wright, Anne L.; Wright, Rosalind Jo; Togias, Alkis; Gergen, Peter J. (Elsevier BV, 2014)
      Population-based birth cohorts on asthma and allergies increasingly provide new insights into the development and natural history of the diseases. Over 130 birth cohorts focusing on asthma and allergy have been initiated ...
    • Birth Order and Suicide in Adulthood: Evidence From Swedish Population Data 

      Rostila, M.; Saarela, J.; Kawachi, I. (, 2014)
      Each year, almost 1 million people die from suicide, which is among the leading causes of death in young people. We studied how birth order was associated with suicide and other main causes of death. A follow-up study based ...
    • Birth weight and later life adherence to unhealthy lifestyles in predicting type 2 diabetes: prospective cohort study 

      Li, Yanping; Ley, Sylvia H; Tobias, Deirdre K; Chiuve, Stephanie E; VanderWeele, Tyler J; Rich-Edwards, Janet W; Curhan, Gary C; Willett, Walter C; Manson, JoAnn E; Hu, Frank B; Qi, Lu (BMJ Publishing Group Ltd., 2015)
      Objectives To prospectively assess the joint association of birth weight and established lifestyle risk factors in adulthood with incident type 2 diabetes and to quantitatively decompose the attributing effects to birth ...
    • Birth Weight for Gestational Age Norms for a Large Cohort of Infants Born to HIV-Negative Women in Botswana Compared with Norms for U.S.-Born Black Infants 

      Parekh, Natasha K; Binda, Kelebogile; Souda, Sajini; Essex, Max; Matthews, Lynn Turner; Ribaudo, Heather J.; Chen, Jennifer Yin-zu; Ogwu, Anthony; Makhema, Joseph Moeketsi; Lockman, Shahin; Shapiro, Roger L. (BioMed Central, 2011)
      Background: Standard values for birth weight by gestational age are not available for sub-Saharan Africa, but are needed to evaluate incidence and risk factors for intrauterine growth retardation in settings where HIV, ...
    • Birth Weight, Genetic Susceptibility, and Adulthood Risk of Type 2 Diabetes 

      Li, Yanping; Qi, Qibin; Workalemahu, Tsegaselassie; Hu, Frank B.; Qi, Lu (American Diabetes Association, 2012)
      OBJECTIVE Both stressful intrauterine milieus and genetic susceptibility have been linked to later-life diabetes risk. The current study aims to examine the interaction between low birth weight, a surrogate measure of ...
    • Birth weight-for-gestational age is associated with DNA methylation at birth and in childhood 

      Agha, Golareh; Hajj, Hanine; Rifas-Shiman, Sheryl L.; Just, Allan C.; Hivert, Marie-France; Burris, Heather H.; Lin, Xihong; Litonjua, Augusto A.; Oken, Emily; DeMeo, Dawn L.; Gillman, Matthew W.; Baccarelli, Andrea A. (BioMed Central, 2016)
      Background: Both higher and lower fetal growth are associated with cardio-metabolic health later in life, suggesting that prenatal developmental programming determines long-term cardiovascular disease risk. Epigenetic ...
    • Birthweight in a fishing community: significance of essential fatty acids and marine food contaminants 

      Grandjean, Philippe; Bjerve, Kristian S; Weihe, Pal; Steuerwald, Ulrike (Oxford University Press (OUP), 2001)
      Background Marine food provides essential fatty acids that are important during pregnancy, but the benefits may be limited at high intakes and by seafood contaminants. Methods In the fishing community of the Faroe Islands, ...