Browsing SPH Scholarly Articles by Keyword "C-reactive protein"

Now showing items 1-7 of 7

    • Are Statins Anti-Inflammatory? 

      Blake, Gavin J.; Ridker, Paul M. (BioMed Central, 2000)
      Large scale clinical trials demonstrate significant reductions in cardiovascular event rates with statin therapy. The observed benefit of statin therapy, however, may be larger in these trials than that expected on the ...

    • Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation 

      Ligthart, Symen; Vaez, Ahmad; Hsu, Yi-Hsiang; Stolk, Ronald; Uitterlinden, André G.; Hofman, Albert; Alizadeh, Behrooz Z.; Franco, Oscar H.; Dehghan, Abbas (BioMed Central, 2016)
      Background: Genome-wide association studies (GWAS) have identified multiple genetic loci for C-reactive protein (CRP) and lipids, of which some overlap. We aimed to identify genetic pleiotropy among CRP and lipids in order ...

    • C-reactive protein independently predicts HIV-related outcomes among women and children in a resource-poor setting 

      Drain, Paul K; Kupka, Roland; Msamanga, Gernard I; Urassa, Willy; Mugusi, Ferdinand; Fawzi, Wafaie W. (Ovid Technologies (Wolters Kluwer Health), 2007)
      Objective To evaluate C-reactive protein (CRP), an inflammatory marker, as a predictor of HIV-related outcomes among women and children in a resource-poor setting. Design We measured serum CRP concentration among ...

    • A cross sectional study of anemia and iron deficiency as risk factors for arsenic-induced skin lesions in Bangladeshi women 

      Kile, Molly L.; Faraj, Joycelyn M.; Ronnenberg, Alayne G.; Quamruzzaman, Quazi; Rahman, Mahmudar; Mostofa, Golam; Afroz, Sakila; Christiani, David C. (BioMed Central, 2016)
      Background: In the Ganges Delta, chronic arsenic poisoning is a health concern affecting millions of people who rely on groundwater as their potable water source. The prevalence of anemia is also high in this region, ...

    • Diabetes, Obesity, and Hypertension May Enhance Associations between Air Pollution and Markers of Systemic Inflammation 

      Dubowsky, Sara D.; Suh, Helen; Schwartz, Joel David; Coull, Brent Andrew; Gold, Diane R. (National Institute of Environmental Health Sciences, 2006)
      Airborne particulate matter (PM) may lead to increased cardiac risk through an inflammatory pathway. Therefore, we investigated associations between ambient PM and markers of systemic inflammation among repeated measures ...

    • DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases 

      Ligthart, Symen; Marzi, Carola; Aslibekyan, Stella; Mendelson, Michael M.; Conneely, Karen N.; Tanaka, Toshiko; Colicino, Elena; Waite, Lindsay L.; Joehanes, Roby; Guan, Weihua; Brody, Jennifer A.; Elks, Cathy; Marioni, Riccardo; Jhun, Min A.; Agha, Golareh; Bressler, Jan; Ward-Caviness, Cavin K.; Chen, Brian H.; Huan, Tianxiao; Bakulski, Kelly; Salfati, Elias L.; Fiorito, Giovanni; Wahl, Simone; Schramm, Katharina; Sha, Jin; Hernandez, Dena G.; Just, Allan C.; Smith, Jennifer A.; Sotoodehnia, Nona; Pilling, Luke C.; Pankow, James S.; Tsao, Phil S.; Liu, Chunyu; Zhao, Wei; Guarrera, Simonetta; Michopoulos, Vasiliki J.; Smith, Alicia K.; Peters, Marjolein J.; Melzer, David; Vokonas, Pantel; Fornage, Myriam; Prokisch, Holger; Bis, Joshua C.; Chu, Audrey Y.; Herder, Christian; Grallert, Harald; Yao, Chen; Shah, Sonia; McRae, Allan F.; Lin, Honghuang; Horvath, Steve; Fallin, Daniele; Hofman, Albert; Wareham, Nicholas J.; Wiggins, Kerri L.; Feinberg, Andrew P.; Starr, John M.; Visscher, Peter M.; Murabito, Joanne M.; Kardia, Sharon L. R.; Absher, Devin M.; Binder, Elisabeth B.; Singleton, Andrew B.; Bandinelli, Stefania; Peters, Annette; Waldenberger, Melanie; Matullo, Giuseppe; Schwartz, Joel D.; Demerath, Ellen W.; Uitterlinden, André G.; van Meurs, Joyce B. J.; Franco, Oscar H.; Chen, Yii-Der Ida; Levy, Daniel; Turner, Stephen T.; Deary, Ian J.; Ressler, Kerry J.; Dupuis, Josée; Ferrucci, Luigi; Ong, Ken K.; Assimes, Themistocles L.; Boerwinkle, Eric; Koenig, Wolfgang; Arnett, Donna K.; Baccarelli, Andrea A.; Benjamin, Emelia J.; Dehghan, Abbas (BioMed Central, 2016)
      Background: Chronic low-grade inflammation reflects a subclinical immune response implicated in the pathogenesis of complex diseases. Identifying genetic loci where DNA methylation is associated with chronic low-grade ...

    • Rosuvastatin for primary prevention in patients with European systematic coronary risk evaluation risk ≥5% or Framingham risk >20%: post hoc analyses of the JUPITER trial requested by European health authorities 

      Koenig, Wolfgang; Ridker, Paul M. (Oxford University Press, 2010)
      Aims: On the basis of the JUPITER trial, European health authorities recently approved the use of rosuvastatin to reduce first major cardiovascular events among ‘high' global risk primary prevention patients defined either ...