Browsing SPH Scholarly Articles by Keyword "p53"
Now showing items 1-3 of 3
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Indoor air pollution exposure from use of indoor stoves and fireplaces in association with breast cancer: a case-control study
(BioMed Central, 2014)Background: Previous studies suggest that polycyclic aromatic hydrocarbons (PAHs) may adversely affect breast cancer risk. Indoor air pollution from use of indoor stoves and/or fireplaces is an important source of ambient ... -
Low-dose Arsenic induces chemotherapy protection via p53/NF-κB-mediated metabolic regulation
(2015)Most chemotherapeutical drugs kill cancer cells chiefly by inducing DNA damage, which unfortunately also causes undesirable injuries to normal tissues, mainly due to p53 activation. We report a novel strategy of normal ... -
UXT, a novel MDMX-binding protein, promotes glycolysis by mitigating p53-mediated restriction of NF-κB activity
(Impact Journals LLC, 2015)The importance of stress-induced p53 activation has been extensively investigated and well established. How the basal activity of p53 prevents carcinogenesis, however, remains incompletely understood. We report the ...