Copper-Mediated Amidation of Heterocyclic and Aromatic C−H Bonds

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Copper-Mediated Amidation of Heterocyclic and Aromatic C−H Bonds

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Title: Copper-Mediated Amidation of Heterocyclic and Aromatic C−H Bonds
Author: Wang, Qiu; Schreiber, Stuart L.

Note: Order does not necessarily reflect citation order of authors.

Citation: Wang, Qiu, and Stuart L. Schreiber. 2009. Copper-mediated amidation of heterocyclic and aromatic C−H bonds. Organic Letters 11(22): 5178-5180.
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Abstract: A copper-mediated aerobic coupling reaction enables direct amidation of heterocycles or aromatics having weakly acidic C−H bonds with a variety of nitrogen nucleophiles. These reactions provide efficient access to many biologically important skeletons, including ones with the potential to serve as inhibitors of HMTs.
Published Version: doi:10.1021/ol902079g
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776381/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Open Access Policy Articles, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#OAP
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:4459010

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  • FAS Scholarly Articles [6463]
    Peer reviewed scholarly articles from the Faculty of Arts and Sciences of Harvard University
 
 

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