Cytoplasmic Diffusion: Molecular Motors Mix It Up

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Cytoplasmic Diffusion: Molecular Motors Mix It Up

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Title: Cytoplasmic Diffusion: Molecular Motors Mix It Up
Author: Brangwynne, Clifford P.; Koenderink, Gijsje H.; MacKintosh, Frederick C.; Weitz, David A.

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Citation: Brangwynne, Clifford P., Gijsje H. Koenderink, Frederick C. MacKintosh, and David A. Weitz. 2008. Cytoplasmic diffusion: molecular motors mix it up. The Journal of Cell Biology 183: 583-587.
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Abstract: Random motion within the cytoplasm gives rise to molecular diffusion; this motion is essential to many biological processes. However, in addition to thermal Brownian motion, the cytoplasm also undergoes constant agitation caused by the activity of molecular motors and other nonequilibrium cellular processes. Here, we discuss recent work that suggests this activity can give rise to cytoplasmic motion that has the appearance of diffusion but is significantly enhanced in its magnitude and which can play an important biological role, particularly in cytoskeletal assembly.
Published Version: doi:10.1083/jcb.200806149
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582900/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Open Access Policy Articles, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#OAP
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:4459986

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  • FAS Scholarly Articles [7078]
    Peer reviewed scholarly articles from the Faculty of Arts and Sciences of Harvard University
 
 

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