Forelimb-Hindlimb Developmental Timing Changes across Tetrapod Phylogeny

DSpace/Manakin Repository

Forelimb-Hindlimb Developmental Timing Changes across Tetrapod Phylogeny

Citable link to this page

. . . . . .

Title: Forelimb-Hindlimb Developmental Timing Changes across Tetrapod Phylogeny
Author: Bininda-Emonds, Olaf RP; Jeffery, Jonathan E; Sánchez-Villagra, Marcelo R; Colbert, Matthew; Pieau, Claude; Selwood, Lynne; ten Cate, Carel; Raynaud, Albert; Osabutey, Casmile K; Hanken, James; Richardson, Michael K.

Note: Order does not necessarily reflect citation order of authors.

Citation: Bininda-Emonds, Olaf R.P., Jonathan E. Jeffery, Marcelo R. Sánchez-Villagra, James Hanken, Matthew Colbert, Claude Pieau, Lynne Selwood, et al. 2007. Forelimb-hindlimb developmental timing changes across tetrapod phylogeny. BMC Evolutionary Biology 7:182.
Full Text & Related Files:
Abstract: Background: Tetrapods exhibit great diversity in limb structures among species and also between forelimbs and hindlimbs within species, diversity which frequently correlates with locomotor modes and life history. We aim to examine the potential relation of changes in developmental timing (heterochrony) to the origin of limb morphological diversity in an explicit comparative and quantitative framework. In particular, we studied the relative time sequence of development of the forelimbs versus the hindlimbs in 138 embryos of 14 tetrapod species spanning a diverse taxonomic, ecomorphological and life-history breadth. Whole-mounts and histological sections were used to code the appearance of 10 developmental events comprising landmarks of development from the early bud stage to late chondrogenesis in the forelimb and the corresponding serial homologues in the hindlimb. Results: An overall pattern of change across tetrapods can be discerned and appears to be relatively clade-specific. In the primitive condition, as seen in Chondrichthyes and Osteichthyes, the forelimb/pectoral fin develops earlier than the hindlimb/pelvic fin. This pattern is either retained or re-evolved in eulipotyphlan insectivores (= shrews, moles, hedgehogs, and solenodons) and taken to its extreme in marsupials. Although exceptions are known, the two anurans we examined reversed the pattern and displayed a significant advance in hindlimb development. All other species examined, including a bat with its greatly enlarged forelimbs modified as wings in the adult, showed near synchrony in the development of the fore and hindlimbs. Conclusion: Major heterochronic changes in early limb development and chondrogenesis were absent within major clades except Lissamphibia, and their presence across vertebrate phylogeny are not easily correlated with adaptive phenomena related to morphological differences in the adult fore- and hindlimbs. The apparently conservative nature of this trait means that changes in chondrogenetic patterns may serve as useful phylogenetic characters at higher taxonomic levels in tetrapods. Our results highlight the more important role generally played by allometric heterochrony in this instance to shape adult morphology.
Published Version: doi:10.1186/1471-2148-7-182
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194785/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:4461122

Show full Dublin Core record

This item appears in the following Collection(s)

  • FAS Scholarly Articles [7495]
    Peer reviewed scholarly articles from the Faculty of Arts and Sciences of Harvard University
 
 

Search DASH


Advanced Search
 
 

Submitters