The p38 MAPK Family, a Pushmi-pullyu of Skeletal Muscle Differentiation

The p38 MAPK Family, a Pushmi-pullyu of Skeletal Muscle Differentiation

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The p38 MAPK Family, a Pushmi-pullyu of Skeletal Muscle Differentiation

dc.contributor.author	Lassar, Andrew B.
dc.date.accessioned	2010-12-08T17:14:21Z
dc.date.issued	2009
dc.identifier.citation	Lassar, Andrew B. 2009. The p38 MAPK family, a pushmi-pullyu of skeletal muscle differentiation. The Journal of Cell Biology 187(7): 941-943.	en_US
dc.identifier.issn	0021-9525	en_US
dc.identifier.uri	http://nrs.harvard.edu/urn-3:HUL.InstRepos:4621009
dc.description.abstract	In this issue, Gillespie et al. (Gillespie et al. 2009. J. Cell Biol. doi:10.1083/jcb.200907037) demonstrate that the mitogen-activated protein kinase isoform p38-γ plays a crucial role in blocking the premature differentiation of satellite cells, a skeletal muscle stem cell population. p38-γ puts the brakes on skeletal muscle differentiation by promoting the association of the transcription factor MyoD with the histone methyltransferase, KMT1A, which act together in a complex to repress the premature expression of the gene encoding the myogenic transcription factor Myogenin.	en_US
dc.language.iso	en_US	en_US
dc.publisher	The Rockefeller University Press	en_US
dc.relation.isversionof	doi:10.1083/jcb.200911123	en_US
dc.relation.hasversion	http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806286/pdf/	en_US
dash.license	LAA
dc.title	The p38 MAPK Family, a Pushmi-pullyu of Skeletal Muscle Differentiation	en_US
dc.type	Journal Article	en_US
dc.description.version	Version of Record	en_US
dc.relation.journal	The Journal of Cell Biology	en_US
dash.depositing.author	Lassar, Andrew B.
dc.date.available	2010-12-08T17:14:21Z
dash.affiliation.other	HMS^Biological Chemistry and Molecular Pharmacology	en_US