The p38 MAPK Family, a Pushmi-pullyu of Skeletal Muscle Differentiation

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The p38 MAPK Family, a Pushmi-pullyu of Skeletal Muscle Differentiation

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dc.contributor.author Lassar, Andrew B.
dc.date.accessioned 2010-12-08T17:14:21Z
dc.date.issued 2009
dc.identifier.citation Lassar, Andrew B. 2009. The p38 MAPK family, a pushmi-pullyu of skeletal muscle differentiation. The Journal of Cell Biology 187(7): 941-943. en_US
dc.identifier.issn 0021-9525 en_US
dc.identifier.uri http://nrs.harvard.edu/urn-3:HUL.InstRepos:4621009
dc.description.abstract In this issue, Gillespie et al. (Gillespie et al. 2009. J. Cell Biol. doi:10.1083/jcb.200907037) demonstrate that the mitogen-activated protein kinase isoform p38-γ plays a crucial role in blocking the premature differentiation of satellite cells, a skeletal muscle stem cell population. p38-γ puts the brakes on skeletal muscle differentiation by promoting the association of the transcription factor MyoD with the histone methyltransferase, KMT1A, which act together in a complex to repress the premature expression of the gene encoding the myogenic transcription factor Myogenin. en_US
dc.language.iso en_US en_US
dc.publisher The Rockefeller University Press en_US
dc.relation.isversionof doi:10.1083/jcb.200911123 en_US
dc.relation.hasversion http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806286/pdf/ en_US
dash.license LAA
dc.title The p38 MAPK Family, a Pushmi-pullyu of Skeletal Muscle Differentiation en_US
dc.type Journal Article en_US
dc.description.version Version of Record en_US
dc.relation.journal The Journal of Cell Biology en_US
dash.depositing.author Lassar, Andrew B.
dc.date.available 2010-12-08T17:14:21Z
dash.affiliation.other HMS^Biological Chemistry and Molecular Pharmacology en_US

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