| Title: | P04-41. Kinetics of Antibody Neutralization and Viral Evolution Following Envelope Vaccination in SIV-infected Rhesus Monkeys |
| Author: |
Basavapathruni, A; Coffey, R; Hraber, P; Giri, A; Mascola, J; Nabel, G; Korber, B; Yeh, Wendy Wen-Li; Whitney, James B.; Rao, Sowmya R.; Seaman, Michael S.; Letvin, Norman Lee
Note: Order does not necessarily reflect citation order of authors. |
| Citation: | Basavapathruni, A, W Yeh, R Coffey, J Whitney, P Hraber, A Giri, S Rao, et al. 2009. P04-41. Kinetics of antibody neutralization and viral evolution following envelope vaccination in SIV-infected rhesus monkeys. Retrovirology 6(Suppl 3): P69. |
| Full Text & Related Files: |
2767972.pdf (132.5Kb; PDF)
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| Abstract: | Poster presentation. Conclusion: Our results indicate that env vaccination is associated with an accelerated development of autologous neutralizing antibodies. These antibodies were focused at least in part on the V1 region of Env, since there was selective pressure in this region of the envelope for the evolution of mutational changes. |
| Published Version: | doi://10.1186/1742-4690-6-S3-P69 |
| Other Sources: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2767972/pdf/ |
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| Citable link to this page: | http://nrs.harvard.edu/urn-3:HUL.InstRepos:4706588 |
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