dc.contributor.author | Balague Ponz, Olga | |
dc.contributor.author | Ott, German | |
dc.contributor.author | Hasserjian, Robert Paul | |
dc.contributor.author | Elenitoba-Johnson, Kojo S. J. | |
dc.contributor.author | de Leval, Laurence | |
dc.contributor.author | de Jong, Daphne | |
dc.date.accessioned | 2011-02-20T15:47:08Z | |
dc.date.issued | 2009 | |
dc.identifier.citation | Balague Ponz, Olga, German Ott, Robert P. Hasserjian, Kojo S. J. Elenitoba-Johnson, Laurence de Leval, and Daphne de Jong. 2009. Commentary on the WHO classification of tumors of lymphoid tissues (2008): Aggressive B-cell lymphomas. Journal of Hematopathology 2(2): 83-87. | en_US |
dc.identifier.issn | 1865-5785 | en_US |
dc.identifier.uri | http://nrs.harvard.edu/urn-3:HUL.InstRepos:4728486 | |
dc.description.abstract | In the novel WHO classification 2008, the classification of aggressive B-cell lymphoma has been revised for several categories with the aim to define “clean” entities. Within large B-cell lymphoma, a few distinct clinico-pathological entities have been recognized with more clinically defined entities than pathologically defined ones. The majority of known morphological variations were not considered to merit more than classification as a variant of DLBCL, not otherwise specified. Specifically, a biological subgrouping of DLBCL on the basis of molecular (activated B-cell versus germinal center B-cell) or immunophenotypic (CD5+) features was felt to be too immature to include at this stage. The role of EBV in aggressive B-cell lymphoma has been explored in more depth with the recognition of several novel and re-defined clinico-pathological entities. Also, in these diseases, clinical definitions play a very dominant role in the WHO classification 2008. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Springer Verlag | en_US |
dc.relation.isversionof | doi:10.1007/s12308-009-0038-8 | en_US |
dc.relation.hasversion | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725286/pdf/ | en_US |
dash.license | LAA | |
dc.subject | diffuse large B-cell lymphoma | en_US |
dc.subject | clinico-pathological entity | en_US |
dc.subject | EBV | en_US |
dc.subject | immunodeficiency | en_US |
dc.subject | classification | en_US |
dc.subject | WHO | en_US |
dc.title | Commentary on the WHO Classification of Tumors of Lymphoid Tissues (2008): Aggressive B-cell Lymphomas | en_US |
dc.type | Journal Article | en_US |
dc.description.version | Version of Record | en_US |
dc.relation.journal | Journal of Hematopathology | en_US |
dash.depositing.author | Hasserjian, Robert Paul | |
dc.date.available | 2011-02-20T15:47:08Z | |
dash.affiliation.other | HMS^Pathology | en_US |
dc.identifier.doi | 10.1007/s12308-009-0038-8 | * |
dash.contributor.affiliated | Hasserjian, Robert | |