A software tool for creating simulated outbreaks to benchmark surveillance systems

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A software tool for creating simulated outbreaks to benchmark surveillance systems

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Title: A software tool for creating simulated outbreaks to benchmark surveillance systems
Author: Cassa, Christopher Anthony; Iancu, Karin; Olson, Karen Lea; Mandl, Kenneth David

Note: Order does not necessarily reflect citation order of authors.

Citation: Cassa, Christopher A., Karin Iancu, Karen L. Olson, and Kenneth D. Mandl. 2005. A software tool for creating simulated outbreaks to benchmark surveillance systems. BMC Medical Informatics and Decision Making 5: 22.
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Abstract: Background: Evaluating surveillance systems for the early detection of bioterrorism is particularly challenging when systems are designed to detect events for which there are few or no historical examples. One approach to benchmarking outbreak detection performance is to create semi-synthetic datasets containing authentic baseline patient data (noise) and injected artificial patient clusters, as signal. Methods: We describe a software tool, the AEGIS Cluster Creation Tool (AEGIS-CCT), that enables users to create simulated clusters with controlled feature sets, varying the desired cluster radius, density, distance, relative location from a reference point, and temporal epidemiological growth pattern. AEGIS-CCT does not require the use of an external geographical information system program for cluster creation. The cluster creation tool is an open source program, implemented in Java and is freely available under the Lesser GNU Public License at its Sourceforge website. Cluster data are written to files or can be appended to existing files so that the resulting file will include both existing baseline and artificially added cases. Multiple cluster file creation is an automated process in which multiple cluster files are created by varying a single parameter within a user-specified range. To evaluate the output of this software tool, sets of test clusters were created and graphically rendered. Results: Based on user-specified parameters describing the location, properties, and temporal pattern of simulated clusters, AEGIS-CCT created clusters accurately and uniformly. Conclusion: AEGIS-CCT enables the ready creation of datasets for benchmarking outbreak detection systems. It may be useful for automating the testing and validation of spatial and temporal cluster detection algorithms.
Published Version: doi:10.1186/1472-6947-5-22
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182374/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:4738539

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