Cytological profiling: providing more haystacks for chemists' needles
| Title: | Cytological profiling: providing more haystacks for chemists' needles |
| Author: |
Lorang, Janet; King, Randall Wharton
Note: Order does not necessarily reflect citation order of authors. |
| Citation: | Lorang, Janet and Randall W. King. 2005. Cytological profiling: providing more haystacks for chemists' needles. Genome Biology 6(8): 228. |
| Full Text & Related Files: |
1273624.pdf (65.54Kb; PDF) 
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| Abstract: | Conventional high-throughput ‘chemical genetic’ screening seeks to identify small-molecule inhibitors of a specific protein or pathway. A recent study describes how unbiased screening of cellular morphology, followed by affinity purification to identify targets of compounds with interesting effects, can lead to the identification of novel inhibitors. |
| Published Version: | doi:10.1186/gb-2005-6-8-228 |
| Other Sources: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1273624/pdf/ |
| Terms of Use: | This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA |
| Citable link to this page: | http://nrs.harvard.edu/urn-3:HUL.InstRepos:4743815 |
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