UniPROBE, Update 2011: Expanded Content and Search Tools in the Online Database of Protein-Binding Microarray Data on Protein–DNA Interactions
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UniPROBE, Update 2011: Expanded Content and Search Tools in the Online Database of Protein-Binding Microarray Data on Protein–DNA Interactions
| Title: | UniPROBE, Update 2011: Expanded Content and Search Tools in the Online Database of Protein-Binding Microarray Data on Protein–DNA Interactions |
| Author: |
Robasky, Kimberly; Bulyk, Martha Leonia
Note: Order does not necessarily reflect citation order of authors. |
| Citation: | Robasky, Kimberly, and Martha L. Bulyk. 2011. UniPROBE, update 2011: expanded content and search tools in the online database of protein-binding microarray data on proteinâ DNA interactions. Nucleic Acids Research 39(Database issue): D124-D128. |
| Full Text & Related Files: |
3013812.pdf (7.095Mb; PDF) 
|
| Abstract: | The Universal PBM Resource for Oligonucleotide-Binding Evaluation (UniPROBE) database is a centralized repository of information on the DNA-binding preferences of proteins as determined by universal protein-binding microarray (PBM) technology. Each entry for a protein (or protein complex) in UniPROBE provides the quantitative preferences for all possible nucleotide sequence variants (‘words’) of length k (‘k-mers’), as well as position weight matrix (PWM) and graphical sequence logo representations of the k-mer data. In this update, we describe >130% expansion of the database content, incorporation of a protein BLAST (blastp) tool for finding protein sequence matches in UniPROBE, the introduction of UniPROBE accession numbers and additional database enhancements. The UniPROBE database is available at http://uniprobe.org. |
| Published Version: | doi://10.1093/nar/gkq992 |
| Other Sources: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013812/pdf/ |
| Terms of Use: | This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA |
| Citable link to this page: | http://nrs.harvard.edu/urn-3:HUL.InstRepos:4745741 |
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