UniPROBE, Update 2011: Expanded Content and Search Tools in the Online Database of Protein-Binding Microarray Data on Protein–DNA Interactions

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UniPROBE, Update 2011: Expanded Content and Search Tools in the Online Database of Protein-Binding Microarray Data on Protein–DNA Interactions

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dc.contributor.author Robasky, Kimberly
dc.contributor.author Bulyk, Martha Leonia
dc.date.accessioned 2011-03-19T08:49:13Z
dc.date.issued 2010
dc.identifier.citation Robasky, Kimberly, and Martha L. Bulyk. 2011. UniPROBE, update 2011: expanded content and search tools in the online database of protein-binding microarray data on proteinâ DNA interactions. Nucleic Acids Research 39(Database issue): D124-D128. en_US
dc.identifier.issn 0305-1048 en_US
dc.identifier.uri http://nrs.harvard.edu/urn-3:HUL.InstRepos:4745741
dc.description.abstract The Universal PBM Resource for Oligonucleotide-Binding Evaluation (UniPROBE) database is a centralized repository of information on the DNA-binding preferences of proteins as determined by universal protein-binding microarray (PBM) technology. Each entry for a protein (or protein complex) in UniPROBE provides the quantitative preferences for all possible nucleotide sequence variants (‘words’) of length k (‘k-mers’), as well as position weight matrix (PWM) and graphical sequence logo representations of the k-mer data. In this update, we describe >130% expansion of the database content, incorporation of a protein BLAST (blastp) tool for finding protein sequence matches in UniPROBE, the introduction of UniPROBE accession numbers and additional database enhancements. The UniPROBE database is available at http://uniprobe.org. en_US
dc.language.iso en_US en_US
dc.publisher Oxford University Press en_US
dc.relation.isversionof doi://10.1093/nar/gkq992 en_US
dc.relation.hasversion http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013812/pdf/ en_US
dash.license LAA
dc.title UniPROBE, Update 2011: Expanded Content and Search Tools in the Online Database of Protein-Binding Microarray Data on Protein–DNA Interactions en_US
dc.type Journal Article en_US
dc.description.version Version of Record en_US
dc.relation.journal Nucleic Acids Research en_US
dash.depositing.author Bulyk, Martha Leonia
dc.date.available 2011-03-19T08:49:13Z
dash.affiliation.other HMS^Pathology en_US
dash.affiliation.other HMS^Medicine-Brigham and Women's Hospital en_US

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