Does FXIII Deficiency Impair Wound Healing after Myocardial Infarction?

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Does FXIII Deficiency Impair Wound Healing after Myocardial Infarction?

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Title: Does FXIII Deficiency Impair Wound Healing after Myocardial Infarction?
Author: Ertl, Georg; Nahrendorf, Matthias; Weissleder, Ralph

Note: Order does not necessarily reflect citation order of authors.

Citation: Nahrendorf, Matthias, Ralph Weissleder, and Georg Ertl. 2006. Does FXIII deficiency impair wound healing after myocardial infarction? PLoS ONE 1(1): e48.
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Abstract: Inadequate healing of myocardial infarction may contribute to local expansion of the infarct, frequently leading to chamber dilation, heart failure, or myocardial rupture. Experimental evidence in mouse models suggests that Factor XIII might play a key role in wound healing, and low persistent values lead to increased incidence of cardiac rupture following myocardial infarction. Here we would like to share our initial clinical experiences with strikingly similar observations in patients with this grave disease, and compare these observations to experimental findings.
Published Version: doi:10.1371/journal.pone.0000048
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762326/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:4777433

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