Imaging of the unstable plaque: how far have we got?

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Imaging of the unstable plaque: how far have we got?

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Title: Imaging of the unstable plaque: how far have we got?
Author: Matter, Christian M.; Stuber, Matthias; Nahrendorf, Matthias

Note: Order does not necessarily reflect citation order of authors.

Citation: Matter, Christian M., Matthias Stuber, and Matthias Nahrendorf. 2009. Imaging of the unstable plaque: how far have we got?. European Heart Journal 30(21): 2566-2574.
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Abstract: Rupture of unstable plaques may lead to myocardial infarction or stroke and is the leading cause of morbidity and mortality in western countries. Thus, there is a clear need for identifying these vulnerable plaques before the rupture occurs. Atherosclerotic plaques are a challenging imaging target as they are small and move rapidly, especially in the coronary tree. Many of the currently available imaging tools for clinical use still provide minimal information about the biological characteristics of plaques, because they are limited with respect to spatial and temporal resolution. Moreover, many of these imaging tools are invasive. The new generation of imaging modalities such as magnetic resonance imaging, nuclear imaging such as positron emission tomography and single photon emission computed tomography, computed tomography, fluorescence imaging, intravascular ultrasound, and optical coherence tomography offer opportunities to overcome some of these limitations. This review discusses the potential of these techniques for imaging the unstable plaque.
Published Version: doi://10.1093/eurheartj/ehp419
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771148/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:4815536

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