Tobacco smoking as a risk factor of bronchioloalveolar carcinoma of the lung: pooled analysis of seven case–control studies in the International Lung Cancer Consortium (ILCCO)

DSpace/Manakin Repository

Tobacco smoking as a risk factor of bronchioloalveolar carcinoma of the lung: pooled analysis of seven case–control studies in the International Lung Cancer Consortium (ILCCO)

Citable link to this page

. . . . . .

Title: Tobacco smoking as a risk factor of bronchioloalveolar carcinoma of the lung: pooled analysis of seven case–control studies in the International Lung Cancer Consortium (ILCCO)
Author: Jayaprakash, Vijayvel; Yang, Ping; Muscat, Joshua E.; Schwartz, Ann G.; Zhang, Zuo-Feng; Le Marchand, Loic; Cote, Michele L.; Stoddard, Shawn M.; Morgenstern, Hal; Hung, Rayjean J.; Boffetta, Paolo; Asomaning, Kofi; Christiani, David C.

Note: Order does not necessarily reflect citation order of authors.

Citation: Boffetta, Paolo, Vijayvel Jayaprakash, Ping Yang, Kofi Asomaning, Joshua E. Muscat, Ann G. Schwartz, Zuo-Feng Zhang, et al. 2010. Tobacco smoking as a risk factor of bronchioloalveolar carcinoma of the lung: pooled analysis of seven case–control studies in the International Lung Cancer Consortium (ILCCO). Cancer Causes & Control 22(1): 73-79.
Full Text & Related Files:
Abstract: Background: The International Lung Cancer Consortium (ILCCO) was established in 2004, based on the collaboration of research groups leading large molecular epidemiology studies of lung cancer that are ongoing or have been recently completed. This framework offered the opportunity to investigate the role of tobacco smoking in the development of bronchioloalveolar carcinoma (BAC), a rare form of lung cancer. Methods: Our pooled data comprised seven case–control studies from the United States, with detailed information on tobacco smoking and histology, which contributed 799 cases of BAC and 15,859 controls. We estimated the odds ratio of BAC for tobacco smoking, using never smokers as a referent category, after adjustment for age, sex, race, and study center. Results: The odds ratio of BAC for ever smoking was 2.47 (95% confidence interval [CI] 2.08, 2.93); the risk increased linearly with duration, amount, and cumulative cigarette smoking and persisted long after smoking cessation. The proportion of BAC cases attributable to smoking was 0.47 (95% CI 0.39, 0.54). Conclusions: This analysis provides a precise estimate of the risk of BAC for tobacco smoking.
Published Version: doi:10.1007/s10552-010-9676-5
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002160/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:4874505

Show full Dublin Core record

This item appears in the following Collection(s)

 
 

Search DASH


Advanced Search
 
 

Submitters