Depressive symptoms and glycemic control in adolescents with type 1 diabetes

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Depressive symptoms and glycemic control in adolescents with type 1 diabetes

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Title: Depressive symptoms and glycemic control in adolescents with type 1 diabetes
Author: McGrady, Meghan E.; Drotar, Dennis; Repaske, David; Hood, Korey K.; Laffel, Lori Michelle Burtz

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Citation: McGrady, Meghan E., Lori Laffel, Dennis Drotar, David Repaske, and Korey K. Hood. 2009. Depressive symptoms and glycemic control in adolescents with type 1 diabetes. Diabetes Care 32(5): 804-806.
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Abstract: OBJECTIVE—To determine whether the association between depressive symptoms and glycemic control is mediated by blood glucose monitoring (BGM). RESEARCH DESIGN AND METHODS—A total of 276 adolescents with type 1 diabetes (mean age ± SD, 15.6 ± 1.4 years) completed a measure of depressive symptoms. Sociodemographic and family characteristics were obtained from caregivers. BGM frequency and glycemic control were obtained at a clinic visit. RESULTS—Separate regression analyses revealed that depressive symptoms were associated with lower BGM frequency (B = −0.03; P = 0.04) and higher A1C (B = 0.03; P = 0.05) and that lower BGM frequency was associated with higher A1C (B = −0.39; P < 0.001). With depressive symptoms and BGM frequency included together, only BGM frequency was associated with A1C and depressive symptoms became nonsignificant (B = 0.02; P = 0.19). The Sobel test was significant (Z = 1.96; P < 0.05) and showed that 38% of the depression-A1C link can be explained by BGM. CONCLUSIONS—BGM is a mediator between depressive symptoms and glycemic control in adolescents with type 1 diabetes.
Published Version: doi:10.2337/dc08-2111
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671131/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:4874780

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