Customized Care 2020: How Medical Sequencing and Network Biology Will Enable Personalized Medicine

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Customized Care 2020: How Medical Sequencing and Network Biology Will Enable Personalized Medicine

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Title: Customized Care 2020: How Medical Sequencing and Network Biology Will Enable Personalized Medicine
Author: Hill, Colin; Boguski, Mark S.; Arnaout, Ramy

Note: Order does not necessarily reflect citation order of authors.

Citation: Boguski, Mark S., Ramy Arnaout, and Colin Hill. 2009. Customized care 2020: how medical sequencing and network biology will enable personalized medicine. F1000 Biology Reports 1: 73.
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Abstract: Applications of next-generation nucleic acid sequencing technologies will lead to the development of precision diagnostics that will, in turn, be a major technology enabler of precision medicine. Terabyte-scale, multidimensional data sets derived using these technologies will be used to reverse engineer the specific disease networks that underlie individual patients’ conditions. Modeling and simulation of these networks in the presence of virtual drugs, and combinations of drugs, will identify the most efficacious therapy for precision medicine and customized care. In coming years the practice of medicine will routinely employ network biology analytics supported by high-performance supercomputing.
Published Version: doi:10.3410/B1-73
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948270/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:4874781

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