Protein knot server: detection of knots in protein structures

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Protein knot server: detection of knots in protein structures

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Title: Protein knot server: detection of knots in protein structures
Author: Kolesov, Grigory; Virnau, Peter; Kardar, Mehran; Mirny, Leonid Alex

Note: Order does not necessarily reflect citation order of authors.

Citation: Kolesov, Grigory, Peter Virnau, Mehran Kardar, and Leonid A. Mirny. 2007. Protein knot server: detection of knots in protein structures. Nucleic Acids Research 35: W425-W428.
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Abstract: KNOTS (http://knots.mit.edu) is a web server that detects knots in protein structures. Several protein structures have been reported to contain intricate knots. The physiological role of knots and their effect on folding and evolution is an area of active research. The user submits a PDB id or uploads a 3D protein structure in PDB or mmCIF format. The current implementation of the server uses the Alexander polynomial to detect knots. The results of the analysis that are presented to the user are the location of the knot in the structure, the type of the knot and an interactive visualization of the knot. The results can also be downloaded and viewed offline. The server also maintains a regularly updated list of known knots in protein structures.
Published Version: doi:10.1093/nar/gkm312
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933242/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:4874789

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