Browsing FAS Theses and Dissertations by Title
Now showing items 1074-1093 of 6136
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Delineating HIV-1 Evolutionary Pathways in an Individual With a Broadly Neutralizing Antibody Response
(2020-09-08)Despite the identification of potent broadly neutralizing antibodies (bNAbs) against HIV-1, such as VRC01 and VRC13, the induction of bNAbs through vaccination remains hindered due to an incomplete understanding of the ... -
Delivering Across Boundaries: Social and Structural Features of Service Integration
(2018-05-14)The ability to integrate services across settings and time is increasingly important for healthcare delivery organizations. This dissertation explores the organizational structures and social behaviors that enable service ... -
Delivering the Lotus-Born: Historiography in the Tibetan Renaissance
(2013-02-19)Traditionally recognized as the first of the great Buddhist treasure revealers, Nyang-rel Nyima Özer (1124-1192) historiographically reconstructed the Imperium into a golden age of Tibetan Buddhism. An analysis of his two ... -
Delivering the Right Amount of Care – Sometimes Less Is More
(2017-05-15)New technologies utilized in clinical practice offer improved tools for diagnosing and treating patients. In some cases, these improvements cause unintended consequences by leading to the diagnosis of indolent or otherwise ... -
Demand for Redistribution in the Age of Inequality
(2014-10-21)This dissertation investigates the dynamics of mass attitudes toward redistributive social policies in post-industrial democracies: How have these attitudes changed over time? What factors and mechanisms drive these changes? ... -
Democracy and the University: America and the Reconstruction of German Higher Education, 1945-1966
(2023-06-01)This dissertation explores the intellectual and practical debates over the role of the university in a democratic society by examining the reconstruction and reorientation of German universities in the aftermath of the ... -
Democracy Beyond Disclosure: Secrecy, Transparency, and the Logic of Self-Government
(2017-01-19)"Transparency" is the constant refrain of democratic politics, a promised aid to accountability and integrity in public life. Secrecy is stigmatized as a work of corruption, tolerable (if at all) by a compromise of democratic ... -
Democratic Equality in the Misinformation Age
(2022-11-23)Conventional wisdom blames the “epistemic crisis” of American politics on the leveling force of social media and the collapse of traditional gatekeepers. This dissertation argues democracy’s vulnerability to misinformation ... -
Democratic Performances: How Theater Creates the People
(2023-06-01)This work offers the concept of “democratic performance” as a corollary of “people’s theater.” “People’s theater” is a branch of the performing arts that aims to engage a particular audience, which is made of new spectators, ... -
Democratic Theory and the Question of Character
(2013-02-12)This dissertation uses the history of political thought to shed light on the disconnect between the prominent place of judgments about the character in American democratic life, and the marginalized place of those judgments ... -
Democratizing Money: A Political Theory of Policymaking
(2022-06-06)Political theorists have long wrestled with the appropriate role for experts in democracy. Several recent popular movements have sought to reject expert rule by promising to “take back control” or “topple neoliberal elites.” ... -
Demonic (Dis)Possessions: Indigenous Gold from the Colombia-Panama Borderlands
(2024-03-12)This dissertation takes a long view at the marginalization in archaeological models of pre-Conquest metallurgy from northern Chocó and Urabá in the Colombia-Panama borderlands. It was here, where Europeans found—in the ... -
Dendrite Patterning as a Model for Self-Organizing Systems
(2018-01-05)Biological systems self-organize into complex well-ordered structures and can evolve new patterns when perturbed. To identify principles underlying self-organization, I turned to the model organism C. elegans for its ... -
Dendritic branch structure compartmentalizes calcium-dependent plasticity signals and supports the acquisition of complex tuning functions
(2022-05-12)Life as an organism depends on flexible and intelligent neural activity for perceiving the sensory world, constructing models of the environment, and generating adaptive behaviors. It is evident that the collective activity ... -
Denotational Translation Validation
(2013-01-02)In this dissertation we present a simple and scalable system for validating the correctness of low-level program transformations. Proving that program transformations are correct is crucial to the development of security ... -
Density-Based Separations in Aqueous Multiphase Systems: Tools for Biological Research and Low-Cost Diagnostics
(2014-06-06)Cells often exist in heterogeneous mixtures. Density provides a property to separate several types of cells from the mixed sample in which they originate. Density-based separation methods provide a standard method to ... -
Dental-aspirate presents in Greek and Indo-European
(2023-01-18)This work examines the class of Greek presents in -θε/ο- and, by comparison with cognate formations in the other Indo-European daughter languages, attempts to recover the form and function of the dental aspirate suffix in ... -
Dependence on Persons and Dependence on Things in Rousseau's Social, Psychological, and Aesthetic Theory
(2018-03-02)Jean-Jacques Rousseau is often associated with a certain political form of relating to another as a person, where a person is seen as a locus of enforceable demands. Nevertheless, as I argue in this dissertation, Rousseau ... -
Deploying Affect-Inspired Mechanisms to Enhance Agent Decision-Making and Communication
(2012-12-20)Computer agents are required to make appropriate decisions quickly and efficiently. As the environments in which they act become increasingly complex, efficient decision-making becomes significantly more challenging. This ... -
Derivative synthesis of the transcriptional inhibitor α-amanitin and the translational inhibitor cycloheximide
(2021-08-19)The following work focuses on my efforts towards the synthesis of the transcriptional inhibitor a-amanitin and the translational inhibitor cycloheximide as a means to exploit the potential of these natural products as ...