Browsing FAS Theses and Dissertations by Title
Now showing items 163-182 of 6097
-
Advances in the Measurement of the Electron Electric Dipole Moment
(2023-05-10)Searches for the electron electric dipole moment (eEDM) are powerful tests of physics beyond the standard model, as they probe for new evidence of time-reversal violating interactions. In 2018 our ACME collaboration reported ... -
Advances in the Normal-Normal Hierarchical Model
(2014-06-06)This thesis consists of results relating to the theoretical and computational advances in modeling the Normal-Normal hierarchical model. -
Advancing and Applying Precision Genome Editing Technologies
(2021-03-30)Since the discovery of the chemical structure of DNA, researchers have endeavored to understand how the chemical properties of this complex molecule provide a blueprint for biological function. The ability to modulate ... -
Advancing precision genome and transcriptome engineering
(2022-11-23)The cells within all living organisms contain genomic DNA that encodes the information for their structure, function, and capabilities. According to the central dogma of biology, this DNA is transcribed to RNA and this RNA ... -
Advancing the capabilities of base editing and protein delivery
(2023-11-21)Genome editing technologies can in principle enable powerful new therapeutic strategies, including possible cures for deadly genetic disorders. Realizing the therapeutic potential of genome editing requires the ability to ... -
Advection on Graphs
(2017-02-07)We give an overview of advection on graphs and relate it to Markov chains and covering graphs. -
Adverse Birth Outcomes in Botswana: Findings from the Tsepamo Study
(2023-08-08)The Botswana-Harvard AIDS Institute Partnership (BHP) was formed in 1996 between the Government of Botswana’s Ministry of Health and the Harvard T.H. Chan School of Public Health. Research conducted under this partnership ... -
Adverse Experiences, Psychopathology, and Brain Morphology in Longitudinal Cohort Studies
(2023-06-01)Exposure to adverse experiences in childhood, including trauma and poverty, is linked to increased risk for psychopathology, such as depression and posttraumatic stress disorder (PTSD) in adolescence and adulthood. While ... -
Advocacy and Anti-Racism: How Institutions Shape Organizational Responses to Racially Biased Policing in France and the United States
(2017-05-13)Racially biased policing has captured the attention of citizens across the globe. This preoccupation with racial justice and policing is not unique the United States; these questions are on the rise across the Atlantic as ... -
The Aesthetics of Discovery: Text, Image, and the Performance of Knowledge in the Early-Modern Book
(2015-05-21)How does the book-object in early modernity participate in the representation of scientific knowledge? How was the reader meant to approach the book and to comprehend its contents? This project starts from the contention ... -
Affecting Lives: The Politics of Biography in Modern Italy, 1850-1881
(2013-08-09)This study examines the spread of in-life biographies (biographies written and published while their subjects were still alive) in Italy during the later years of the Risorgimento and the early years of Unification. These ... -
Affective and Cognitive Processing in Nonsuicidal Self-Injury
(2014-02-25)Nonsuicidal self-injury (NSSI) is a behavior recently added to the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) as a condition for further study. In this dissertation, I present findings from three studies ... -
African Migrants & Pentecostal World-Making in South Africa
(2022-05-10)This dissertation examines the intersections between African migrant journeys and Pentecostal Christianity in contemporary South Africa. We live in a world ever more in motion, with more international migrants and refugees ... -
After Math: (Re)configuring Minds, Proof, and Computing in the Postwar United States
(2015-01-26)This dissertation examines the history of three early computer programs that were designed to prove mathematical theorems: The Logic Theory Machine, the Program P, and the Automated Reasoning Assistant, all developed between ... -
After-Taste
(2013-08-09)This dissertation investigates the symbolic uses of food in twentieth-century America using, as case studies, major works by Edith Wharton, Toni Morrison, W.H. Auden, and Wallace Stevens. By incorporating different literary ... -
Afterlives of the Culture: Engaging with the Trans-East Asian Cultural Tradition in Modern Chinese, Japanese, Korean, and Taiwanese Literatures, 1880s-1940s
(2014-10-21)This dissertation examines how modern literature in China, Japan, Korea, and Taiwan in the late-nineteenth to the early-twentieth centuries was practiced within contexts of these countries' deeply interrelated literary ... -
Age of Miracles: Religion and Screen Media in Postwar American Fiction
(2014-06-06)This dissertation examines how four postwar American writers, whose lives and fiction reveal a serious and sustained interest in religion and religious belief, treat screen media in their work. More specifically, it argues ... -
The Age of Responsibility: On the Role of Choice, Luck and Personal Responsibility in Contemporary Politics and Philosophy
(2015-01-21)The value of “personal responsibility” increasingly stands at the center of contemporary discussions about distributive justice and the welfare state. While deep disagreements about who is responsible for which acts and ... -
AGE REVERSAL BY TRANSCRIPTOMIC REPROGRAMMING
(2022-11-23)Aging is a progressive multifaceted functional decline of a biological system. Chronic age-related conditions such as cancer, cardiovascular, and neurodegenerative diseases are leading causes of death worldwide. As the ... -
Agent-Based Modeling for Optimal Economic Policy with Exogenous Shocks
(2021-06-17)My thesis explores the application of reinforcement learning and agent-based computational economics to the problem of optimal policy in an environment with exogenous shocks. I develop an agent-based general equilibrium ...