Browsing FAS Theses and Dissertations by Title
Now showing items 295-314 of 6097
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Antigen-specific immune modulation using an injectable biomaterial
(2014-06-06)The field of immunology has advanced tremendously over the last 40 years, with seminal findings that have guided the development of powerful new therapies. However, the ability to induce safe and long-lasting antigen-specific ... -
Antimicrobial Roles for iNKT Cells and GM-CSF in Mycobacterium Tuberculosis Infection
(2014-06-06)Despite effective antibiotics, Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, still infects nearly one-third of the world's population. While key immune factors including CD4+ T cells and IFNg ... -
Any Questions? Polarity as a Window into the Structure of Questions
(2013-09-30)This dissertation investigates the peculiar behavior of negative polarity items in questions and argues that a unified account of their distribution across declarative and interrogative constructions is feasible. These ... -
Apocalypse and the Algorithm: Muslim Spiritual Cultivation as Critique
In this thesis, I advance a Muslim way to think about politics, ground it in an ethics, and then consider what aesthetics accompany that political-ethical orientation. In response to a totalizing and intertwining set of ... -
Apparatus and Methods for a New Measurement of the Electron and Positron Magnetic Moments
(2018-01-05)This thesis presents contributions to two precision measurement experiments: electron and positron $g/2$, and ATRAP antihydrogen spectroscopy. The magnetic moment of the electron in Bohr magnetons, $g/2$, is the most ... -
Application of geospatial analyses for the identification of the favored long-distance routes between Egypt and Punt in pharaonic times.
(2023-05-01)Punt, the fabulous land of the gods, was known to the Egyptians since the Predynastic period. The precious resources from Punt were essential to perform religious rituals and the pharaohs had to insure their continued ... -
Application of noble gas isotopic systems to identify mantle heterogeneities
(2014-10-21)This study addresses the origin of the combined He-Ne-Ar-Xe noble gas isotopic variation in mantle derived oceanic basalts. High precision heavy noble gas compositions of basalts from the Rochambeau Rift along the Northwestern ... -
Application of novel technologies to cardiovascular prevention
(2024-01-11)This dissertation aimed to employ advanced methodologies in machine learning (ML), causal inference, and metabolomics in epidemiological research to contribute to the field of CVD prevention. First, quantifying sodium ... -
Application of the Helium Isotopic System to Accretion of Terrestrial and Extraterrestrial Dust through the Cenozoic
(2013-02-25)The Helium isotopic system provides novel tools to probe the sedimentary record of the earth over the last few hundred million years. Radiogeneically derived \(^4He\) and solar wind implanted \(^3He\) is delivered to ... -
Applications of Coalescent Theory to Introgression Inference and Analysis of Genomic Studies of Sex and Sexuality
(2023-11-21)Coalescent theory uses a backwards-in-time approach to model the genetic ancestry of a sample. The individuals in the sample can be imagined as residing in the same totally mixed population, as in the standard coalescent ... -
Applications of Estimating the Hospitalization Burden of Respiratory Syncytial Virus
(2016-07-06)Annual epidemics of respiratory viruses such as influenza and RSV result in a major burden of associated severe outcomes. Some of those outcomes stem from the underlying health conditions that infected individuals carry, ... -
Applications of High-Resolution Observations of Millimeter Wavelengths
(2015-12-17)nterferometric observations at millimeter wavelengths provide a precious, detailed view of certain astrophysical objects. This thesis is composed of studies that both rely on and enable this technique to study the structure ... -
Applications of Many Body Dynamics of Solid State Systems to Quantum Metrology and Computation
(2013-03-18)This thesis describes aspects of dynamics of solid state systems which are relevant to quantum metrology and computation. It may be divided into three research directions (parts). For the first part, a new method to enhance ... -
Applications of Nonlinear Optics in 3D Direct Laser Writing and Integrated Nanophotonics
(2016-05-17)This thesis presents novel applications of nonlinear optics in laser fabrication and sources of entangled photons for quantum optics. Femtosecond direct laser writing in transparent media enables mask-less fabrication of ... -
Applications of recombineering and recoded genome construction.
(2022-06-06)Genome engineering offers the opportunity to bypass natural selection to generate novel organisms. Although multiple types of genome engineering are currently possible, work described in this dissertation occurred in the ... -
Applications of Vapor Deposition in Microelectronics and Dye-Sensitized Solar Cells
(2012-10-31)Over the past decades, vapor deposition of thin films has gained wide interest in both industry and academia, and a variety of its applications have been demonstrated. As one of the most promising vapor deposition techniques, ... -
Applications of Various Thin Film Deposition Techniques for Oxide Dielectrics, Metal Interconnects and Polymer Insulators
(2022-06-06)As the feature size gradually approaches the physical limit, the downscaling of the semiconductor industry guided by Moore’s law has encounter many challenges. However, recent advances in thin-film materials and deposition ... -
Applying Bayesian Inference to Measurements of Colloidal Dynamics
(2021-05-14)A generative model provides a framework for applying Bayesian methods to complex experimental data like microscope images by describing them as a statistical probability distribution. One of the most valuable features ... -
Applying Next Generation Sequencing to Skeletal Development and Disease
(2014-02-25)Next Generation Sequencing (NGS) technologies have dramatically increased the throughput and lowered the cost of DNA sequencing. In this thesis, I apply these technologies to unresolved questions in skeletal development ... -
Appreciating Housing: The Role of Housing in Politics
(2016-05-03)While the economic implications of housing have been examined extensively, surprisingly limited attention has been devoted to how the housing market impacts politics. My dissertation is a three paper compilation that ...