All for One, and One for All: The Clonality of the Intestinal Stem Cell Niche

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All for One, and One for All: The Clonality of the Intestinal Stem Cell Niche

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Title: All for One, and One for All: The Clonality of the Intestinal Stem Cell Niche
Author: Karpowicz, Phillip Adam; Perrimon, Norbert

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Citation: Karpowicz, Phillip, and Norbert Perrimon. 2010. All for one, and one for all: the clonality of the intestinal stem cell niche. F1000 Biology Reports 2(73).
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Abstract: Intestinal epithelia are maintained by intestinal stem cells (ISCs) that divide to replace dying absorptive and secretory cells that make up this tissue. Lineage labeling studies, both in vertebrates and Drosophila, have revealed the relationships between ISCs and their progeny. In addition, a number of signaling pathways involved in ISC proliferation and differentiation have been identified. Further studies will clarify the signals originating from the ISC niche and determine the processes that control the number and uniform distribution of niches throughout the epithelium.
Published Version: doi://10.3410/B2-73
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989629/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:5346716

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