A Case–Control Analysis of Exposure to Traffic and Acute Myocardial Infarction

DSpace/Manakin Repository

A Case–Control Analysis of Exposure to Traffic and Acute Myocardial Infarction

Citable link to this page

. . . . . .

Title: A Case–Control Analysis of Exposure to Traffic and Acute Myocardial Infarction
Author: Tonne, Cathryn; Goldberg, Robert; Melly, Steven John; Mittleman, Murray A.; Coull, Brent Andrew; Schwartz, Joel David

Note: Order does not necessarily reflect citation order of authors.

Citation: Tonne, Cathryn, Steve Melly, Murray Mittleman, Brent Coull, Robert Goldberg, and Joel Schwartz. 2007. A case-control analysis of exposure to traffic and acute myocardial infarction. Environmental Health Perspectives 115(1): 53-57.
Full Text & Related Files:
Abstract: Background: Long-term exposure to particulate air pollution has been associated with an increased risk of dying from cardiopulmonary and ischemic heart disease, yet few studies have evaluated cardiovascular end points other than mortality. We investigated the relationship between long-term exposure to traffic and occurrence of acute myocardial infarction (AMI) in a case–control study. Methods: A total of 5,049 confirmed cases of AMI were identified between 1995 and 2003 as part of the Worcester Heart Attack Study, a community-wide study examining changes over time in the incidence of AMI among greater Worcester, Massachusetts, residents. Population controls were selected from Massachusetts resident lists. We used cumulative traffic within 100 m of subjects’ residence and distance from major roadway as proxies for exposure to traffic-related air pollution. We estimated the relationship between exposure to traffic and occurrence of AMI using logistic regression, and we adjusted for the following potential confounders: age, sex, section of the study area, point sources emissions of particulate matter with aerodynamic diameter < 2.5 μm, area socioeconomic characteristics, and percentage of open space. Results: An increase in cumulative traffic near the home was associated with a 4% increase in the odds of AMI per interquartile range [95% confidence interval (CI), 2–7%], whereas living near a major roadway was associated with a 5% increase in the odds of AMI per kilometer (95% CI, 3–6%). Conclusions: These results provide support for an association between long-term exposure to traffic and the risk of AMI.
Published Version: doi://10.1289/ehp.9587
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797833/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:5978724

Show full Dublin Core record

This item appears in the following Collection(s)

 
 

Search DASH


Advanced Search
 
 

Submitters