Cortical Folding Patterns and Predicting Cytoarchitecture
View/ Open
Author
Rajendran, Niranjini
Busa, Evelina
Hinds, Oliver
Yeo, Boon Thye Thomas
Mohlberg, Hartmut
Amunts, Katrin
Zilles, Karl
Published Version
https://doi.org/10.1093/cercor/bhm225Metadata
Show full item recordCitation
Fischl, Bruce, Niranjini Rajendran, Evelina Busa, Jean Augustinack, Oliver Hinds, Boon Thye Thomas Yeo, Hartmut Mohlberg, Katrin Amunts, and Karl Zilles. 2008. Cortical Folding Patterns and Predicting Cytoarchitecture. Cerebral Cortex 18(8): 1973-1980.Abstract
The human cerebral cortex is made up of a mosaic of structural areas, frequently referred to as Brodmann areas (BAs). Despite the widespread use of cortical folding patterns to perform ad hoc estimations of the locations of the BAs, little is understood regarding 1) how variable the position of a given BA is with respect to the folds, 2) whether the location of some BAs is more variable than others, and 3) whether the variability is related to the level of a BA in a putative cortical hierarchy. We use whole-brain histology of 10 postmortem human brains and surface-based analysis to test how well the folds predict the locations of the BAs. We show that higher order cortical areas exhibit more variability than primary and secondary areas and that the folds are much better predictors of the BAs than had been previously thought. These results further highlight the significance of cortical folding patterns and suggest a common mechanism for the development of the folds and the cytoarchitectonic fields.Other Sources
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2474454/pdf/Terms of Use
This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAACitable link to this page
http://nrs.harvard.edu/urn-3:HUL.InstRepos:7625541
Collections
- HMS Scholarly Articles [17917]
Contact administrator regarding this item (to report mistakes or request changes)