Are Statins Anti-Inflammatory?

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Are Statins Anti-Inflammatory?

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Title: Are Statins Anti-Inflammatory?
Author: Blake, Gavin J.; Ridker, Paul M.

Note: Order does not necessarily reflect citation order of authors.

Citation: Blake, Gavin J. and Paul M. Ridker. 2000. Are statins anti-inflammatory? Current Controlled Trials in Cardiovascular Medicine 1(3): 161-165.
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Abstract: Large scale clinical trials demonstrate significant reductions in cardiovascular event rates with statin therapy. The observed benefit of statin therapy, however, may be larger in these trials than that expected on the basis of lipid lowering alone. Emerging evidence from both clinical trials and basic science studies suggest that statins have anti-inflammatory properties, which may additionally lead to clinical efficacy. Measurement of markers of inflammation such as high sensitivity C-reactive protein in addition to lipid parameters may help identify those patients who will benefit most from statin therapy.
Published Version: doi:10.1186/cvm-1-3-161
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC59622/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:7692385

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