Are Statins Anti-Inflammatory?

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Are Statins Anti-Inflammatory?

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dc.contributor.author Blake, Gavin J.
dc.contributor.author Ridker, Paul M.
dc.date.accessioned 2012-01-17T15:45:00Z
dc.date.issued 2000
dc.identifier.citation Blake, Gavin J. and Paul M. Ridker. 2000. Are statins anti-inflammatory? Current Controlled Trials in Cardiovascular Medicine 1(3): 161-165. en_US
dc.identifier.issn 1468-6708 en_US
dc.identifier.issn 1468-6694 en_US
dc.identifier.uri http://nrs.harvard.edu/urn-3:HUL.InstRepos:7692385
dc.description.abstract Large scale clinical trials demonstrate significant reductions in cardiovascular event rates with statin therapy. The observed benefit of statin therapy, however, may be larger in these trials than that expected on the basis of lipid lowering alone. Emerging evidence from both clinical trials and basic science studies suggest that statins have anti-inflammatory properties, which may additionally lead to clinical efficacy. Measurement of markers of inflammation such as high sensitivity C-reactive protein in addition to lipid parameters may help identify those patients who will benefit most from statin therapy. en_US
dc.language.iso en_US en_US
dc.publisher BioMed Central en_US
dc.relation.isversionof doi:10.1186/cvm-1-3-161 en_US
dc.relation.hasversion http://www.ncbi.nlm.nih.gov/pmc/articles/PMC59622/pdf/ en_US
dash.license LAA
dc.subject atherosclerosis en_US
dc.subject C-reactive protein en_US
dc.subject inflammation en_US
dc.subject statins en_US
dc.title Are Statins Anti-Inflammatory? en_US
dc.type Journal Article en_US
dc.description.version Version of Record en_US
dc.relation.journal Current Controlled Trials in Cardiovascular Medicine en_US
dash.depositing.author Ridker, Paul M.
dc.date.available 2012-01-17T15:45:00Z
dash.affiliation.other SPH^Epidemiology en_US
dash.affiliation.other HMS^Medicine-Brigham and Women's Hospital en_US

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