Hypoglycemia and Clinical Outcomes in Patients With Diabetes Hospitalized in the General Ward

DSpace/Manakin Repository

Hypoglycemia and Clinical Outcomes in Patients With Diabetes Hospitalized in the General Ward

Citable link to this page

. . . . . .

Title: Hypoglycemia and Clinical Outcomes in Patients With Diabetes Hospitalized in the General Ward
Author: Matheny, Michael E.; Shubina, Maria; Scanlon, James V.; Greenwood, Bonnie; Turchin, Alexander; Pendergrass, Merri L.

Note: Order does not necessarily reflect citation order of authors.

Citation: Turchin, Alexander, Michael E. Matheny, Maria Shubina, James V. Scanlon, Bonnie Greenwood, and Merri L. Pendergrass. 2009. Hypoglycemia and clinical outcomes in patients with diabetes hospitalized in the general ward. Diabetes Care 32(7): 1153-1157.
Access Status: At the direction of the depositing author this work is not currently accessible through DASH.
Full Text & Related Files:
Abstract: OBJECTIVE: Hypoglycemia is associated with adverse outcomes in mixed populations of patients in intensive care units. It is not known whether the same risks exist for diabetic patients who are less severely ill. In this study, we aimed to determine whether hypoglycemic episodes are associated with higher mortality in diabetic patients hospitalized in the general ward. RESEARCH DESIGN AND METHODS: This retrospective cohort study analyzed 4,368 admissions of 2,582 patients with diabetes hospitalized in the general ward of a teaching hospital between January 2003 and August 2004. The associations between the number and severity of hypoglycemic (≤50 mg/dl) episodes and inpatient mortality, length of stay (LOS), and mortality within 1 year after discharge were evaluated. RESULTS: Hypoglycemia was observed in 7.7% of admissions. In multivariable analysis, each additional day with hypoglycemia was associated with an increase of 85.3% in the odds of inpatient death (P = 0.009) and 65.8% (P = 0.0003) in the odds of death within 1 year from discharge. The odds of inpatient death also rose threefold for every 10 mg/dl decrease in the lowest blood glucose during hospitalization (P = 0.0058). LOS increased by 2.5 days for each day with hypoglycemia (P < 0.0001). CONCLUSIONS: Hypoglycemia is common in diabetic patients hospitalized in the general ward. Patients with hypoglycemia have increased LOS and higher mortality both during and after admission. Measures should be undertaken to decrease the frequency of hypoglycemia in this high-risk patient population.
Published Version: doi:10.2337/dc08-2127
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699723/pdf/
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:8191185

Show full Dublin Core record

This item appears in the following Collection(s)

 
 

Search DASH


Advanced Search
 
 

Submitters