Expanding Stereochemical and Skeletal Diversity Using Petasis Reactions and 1,3-Dipolar Cycloadditions

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Expanding Stereochemical and Skeletal Diversity Using Petasis Reactions and 1,3-Dipolar Cycloadditions

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Title: Expanding Stereochemical and Skeletal Diversity Using Petasis Reactions and 1,3-Dipolar Cycloadditions
Author: Kaya, Taner; Kumagai, Naoya; Clemons, Paul A.; Muncipinto, Giovanni; Wilson, J. Anthony; Schreiber, Stuart L.

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Citation: Muncipinto, Giovanni, Taner Kaya, J. Anthony Wilson, Naoya Kumagai, Paul A. Clemons, and Stuart L. Schreiber. 2010. Expanding stereochemical and skeletal diversity using petasis reactions and 1,3-dipolar cycloadditions. Organic Letters 12(22): 5230-5233.
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Abstract: A short and modular synthetic pathway using intramolecular 1,3-dipolar cycloaddition reactions and yielding functionalized isoxazoles, isoxazolines, and isoxazolidines is described. The change in shape of previous compounds and those in this study is quantified and compared using principal moment-of-inertia shape analysis.
Published Version: doi:10.1021/ol102266j
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979010/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:8362455

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  • FAS Scholarly Articles [7587]
    Peer reviewed scholarly articles from the Faculty of Arts and Sciences of Harvard University
 
 

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