Identification of Conserved Aquilegia Coerulea MicroRNAs and Their Targets

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Identification of Conserved Aquilegia Coerulea MicroRNAs and Their Targets

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dc.contributor.author Puzey, Joshua Robert
dc.contributor.author Kramer, Elena M.
dc.date.accessioned 2012-04-06T19:57:14Z
dc.date.issued 2009
dc.identifier.citation Puzey, Joshua Robert, and Elena M. Kramer. 2009. Identification of conserved Aquilegia coerulea microRNAs and their targets. Gene 448(1): 46-56. en_US
dc.identifier.issn 0378-1119 en_US
dc.identifier.issn 1879-0038 en_US
dc.identifier.uri http://nrs.harvard.edu/urn-3:HUL.InstRepos:8519268
dc.description.abstract Aquilegia is an emerging model organism that is phylogenetically intermediate between the core eudicot and monocot models, Arabidopsis and Oryza. In this study, we have used a comparative genomics approach to identify 45 Aquilegia microRNAs that comprise 20 separate plant microRNA families. We have predicted 84 targets of these newly identified Aquilegia microRNAs including transcription factors and loci involved in metabolism, stress responses, transport, and auxin signaling. microRNA families from 16 plant species and the newly identified microRNAs from Aquilegia were analyzed in a phylogenetic context revealing 40 distantly conserved microRNA families. In addition to these highly conserved plant microRNA families, several families with disjointed phylogenetic distribution were identified. This study provides a phylogenetically important dataset for plant microRNA evolution studies. The current study is the first to identify miRNAs in a lower eudicot in which comprehensive genomic resources are becoming available. en_US
dc.description.sponsorship Organismic and Evolutionary Biology en_US
dc.language.iso en_US en_US
dc.publisher Elsevier en_US
dc.relation.isversionof doi:10.1016/j.gene.2009.08.005 en_US
dc.relation.hasversion http://www.ncbi.nlm.nih.gov/pubmed/19699282 en_US
dash.license OAP
dc.subject Aquilegia en_US
dc.subject microRNA en_US
dc.subject evolution en_US
dc.subject angiosperm en_US
dc.title Identification of Conserved Aquilegia Coerulea MicroRNAs and Their Targets en_US
dc.type Journal Article en_US
dc.description.version Author's Original en_US
dc.relation.journal Gene en_US
dash.depositing.author Kramer, Elena M.
dc.date.available 2012-04-06T19:57:14Z

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  • FAS Scholarly Articles [7106]
    Peer reviewed scholarly articles from the Faculty of Arts and Sciences of Harvard University

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