Magnetic Resonance Characterization of Ischemic Tissue Metabolism

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Magnetic Resonance Characterization of Ischemic Tissue Metabolism

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dc.contributor.author Cheung, Jerry S
dc.contributor.author Wang, Xiaoying
dc.contributor.author Sun, Phillip Zhe
dc.date.accessioned 2012-04-08T19:06:49Z
dc.date.issued 2011
dc.identifier.citation Cheung, Jerry S, Xiaoying Wang, and Phillip Zhe Sun. 2011. Magnetic resonance characterization of ischemic tissue metabolism. The Open Neuroimaging Journal 5(Suppl. 1-M2):66-73. en_US
dc.identifier.issn 1874-4400 en_US
dc.identifier.uri http://nrs.harvard.edu/urn-3:HUL.InstRepos:8519640
dc.description.abstract Magnetic resonance imaging (MRI) and spectroscopy (MRS) are versatile diagnostic techniques capable of characterizing the complex stroke pathophysiology, and hold great promise for guiding stroke treatment. Particularly, tissue viability and salvageability are closely associated with its metabolic status. Upon ischemia, ischemic tissue metabolism is disrupted including altered metabolism of glucose and oxygen, elevated lactate production/accumulation, tissue acidification and eventually, adenosine triphosphate (ATP) depletion and energy failure. Whereas metabolism impairment during ischemic stroke is complex, it may be monitored non-invasively with magnetic resonance (MR)-based techniques. Our current article provides a concise overview of stroke pathology, conventional and emerging imaging and spectroscopy techniques, and data analysis tools for characterizing ischemic tissue damage. en_US
dc.language.iso en_US en_US
dc.publisher Bentham Open en_US
dc.relation.isversionof doi:10.2174/1874440001105010066 en_US
dc.relation.hasversion http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245409/pdf/ en_US
dash.license LAA
dc.subject MRI en_US
dc.subject MRS en_US
dc.subject cerebral ischemia en_US
dc.subject metabolism en_US
dc.title Magnetic Resonance Characterization of Ischemic Tissue Metabolism en_US
dc.type Journal Article en_US
dc.description.version Version of Record en_US
dc.relation.journal The Open Neuroimaging Journal en_US
dash.depositing.author Sun, Phillip Zhe
dc.date.available 2012-04-08T19:06:49Z

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