Magnetic Resonance Characterization of Ischemic Tissue Metabolism

Magnetic Resonance Characterization of Ischemic Tissue Metabolism

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Magnetic Resonance Characterization of Ischemic Tissue Metabolism

dc.contributor.author	Cheung, Jerry S
dc.contributor.author	Wang, Xiaoying
dc.contributor.author	Sun, Phillip Zhe
dc.date.accessioned	2012-04-08T19:06:49Z
dc.date.issued	2011
dc.identifier.citation	Cheung, Jerry S, Xiaoying Wang, and Phillip Zhe Sun. 2011. Magnetic resonance characterization of ischemic tissue metabolism. The Open Neuroimaging Journal 5(Suppl. 1-M2):66-73.	en_US
dc.identifier.issn	1874-4400	en_US
dc.identifier.uri	http://nrs.harvard.edu/urn-3:HUL.InstRepos:8519640
dc.description.abstract	Magnetic resonance imaging (MRI) and spectroscopy (MRS) are versatile diagnostic techniques capable of characterizing the complex stroke pathophysiology, and hold great promise for guiding stroke treatment. Particularly, tissue viability and salvageability are closely associated with its metabolic status. Upon ischemia, ischemic tissue metabolism is disrupted including altered metabolism of glucose and oxygen, elevated lactate production/accumulation, tissue acidification and eventually, adenosine triphosphate (ATP) depletion and energy failure. Whereas metabolism impairment during ischemic stroke is complex, it may be monitored non-invasively with magnetic resonance (MR)-based techniques. Our current article provides a concise overview of stroke pathology, conventional and emerging imaging and spectroscopy techniques, and data analysis tools for characterizing ischemic tissue damage.	en_US
dc.language.iso	en_US	en_US
dc.publisher	Bentham Open	en_US
dc.relation.isversionof	doi:10.2174/1874440001105010066	en_US
dc.relation.hasversion	http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245409/pdf/	en_US
dash.license	LAA
dc.subject	MRI	en_US
dc.subject	MRS	en_US
dc.subject	cerebral ischemia	en_US
dc.subject	metabolism	en_US
dc.title	Magnetic Resonance Characterization of Ischemic Tissue Metabolism	en_US
dc.type	Journal Article	en_US
dc.description.version	Version of Record	en_US
dc.relation.journal	The Open Neuroimaging Journal	en_US
dash.depositing.author	Sun, Phillip Zhe
dc.date.available	2012-04-08T19:06:49Z