dc.contributor.author | Nathanson, Eva | |
dc.contributor.author | Lambregts-van Weezenbeek, Catharina | |
dc.contributor.author | Gupta, Rajesh | |
dc.contributor.author | Blöndal, Kai | |
dc.contributor.author | Caminero, José A. | |
dc.contributor.author | Cegielski, J. Peter | |
dc.contributor.author | Danilovits, Manfred | |
dc.contributor.author | Espinal, Marcos A. | |
dc.contributor.author | Hollo, Vahur | |
dc.contributor.author | Jaramillo, Ernesto | |
dc.contributor.author | Leimane, Vaira | |
dc.contributor.author | Nunn, Paul | |
dc.contributor.author | Pasechnikov, Alexander | |
dc.contributor.author | Tupasi, Thelma | |
dc.contributor.author | Wells, Charles | |
dc.contributor.author | Raviglione, Mario C. | |
dc.contributor.author | Rich, Michael Leonard | |
dc.contributor.author | Bayona, Jaime | |
dc.contributor.author | Mitnick, Carole Diane | |
dc.contributor.author | Mukherjee, Joia Stapleton | |
dc.date.accessioned | 2012-04-24T17:47:35Z | |
dc.date.issued | 2006 | |
dc.identifier.citation | Nathanson, Eva, Catharina Lambregts-van Weezenbeek, Michael L. Rich, Rajesh Gupta, Jaime Bayona, Kai Blöndal, José A. Caminero, et al. 2006. Multidrug-resistant tuberculosis management in resource-limited settings. Emerging Infectious Diseases 12(9): 1389-1397. | en_US |
dc.identifier.issn | 1080-6040 | en_US |
dc.identifier.uri | http://nrs.harvard.edu/urn-3:HUL.InstRepos:8609125 | |
dc.description.abstract | Evidence of successful management of multidrug-resistant tuberculosis (MDRTB) is mainly generated from referral hospitals in high-income countries. We evaluate the management of MDRTB in 5 resource-limited countries: Estonia, Latvia, Peru, the Philippines, and the Russian Federation. All projects were approved by the Green Light Committee for access to quality-assured second-line drugs provided at reduced price for MDRTB management. Of 1,047 MDRTB patients evaluated, 119 (11%) were new, and 928 (89%) had received treatment previously. More than 50% of previously treated patients had received both first- and second-line drugs, and 65% of all patients had infections that were resistant to both first- and second-line drugs. Treatment was successful in 70% of all patients, but success rate was higher among new (77%) than among previously treated patients (69%). In resource-limited settings, treatment of MDRTB provided through, or in collaboration with, national TB programs can yield results similar to those from wealthier settings. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Centers for Disease Control and Prevention | en_US |
dc.relation.isversionof | doi:10.3201/eid1209.051618 | en_US |
dc.relation.hasversion | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294733/pdf/ | en_US |
dash.license | LAA | |
dc.title | Multidrug-Resistant Tuberculosis Management in Resource-Limited Settings | en_US |
dc.type | Journal Article | en_US |
dc.description.version | Version of Record | en_US |
dc.relation.journal | Emerging Infectious Diseases | en_US |
dash.depositing.author | Mitnick, Carole Diane | |
dc.date.available | 2012-04-24T17:47:35Z | |
dc.identifier.doi | 10.3201/eid1209.051618 | * |
dash.authorsordered | false | |
dash.contributor.affiliated | Bayona, Jaime | |
dash.contributor.affiliated | Mukherjee, Joia | |
dash.contributor.affiliated | Mitnick, Carole | |
dash.contributor.affiliated | Rich, Michael | |