A Therapeutic Method for the Direct Reprogramming of Human Liver Cancer Cells with only Chemicals

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A Therapeutic Method for the Direct Reprogramming of Human Liver Cancer Cells with only Chemicals

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Title: A Therapeutic Method for the Direct Reprogramming of Human Liver Cancer Cells with only Chemicals
Author: Moriguchi, Hisashi; Mihara, Makoto; Sato, Chifumi; Zhang, Yue

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Citation: Moriguchi, Hisashi, Yue Zhang, Makoto Mihara, and Chifumi Sato. 2012. A therapeutic method for the direct reprogramming of human liver cancer cells with only chemicals. Scientific Reports 2: 280.
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Abstract: Various methods for the direct reprogramming of human somatic cells have been developed. However, a therapeutic method to reprogram and eliminate human solid tumor cells has not been developed. Here we show a novel therapeutic method to reprogram and eliminate human solid tumor cells with chemicals. This therapeutic method may be applicable to various human solid tumor cells that express aldo-keto reductase family 1 member B10 (AKR1B10) and retinoid X receptors (RXRs).
Published Version: doi:10.1038/srep00280
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282982/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:8623556

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