A Therapeutic Method for the Direct Reprogramming of Human Liver Cancer Cells with only Chemicals

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Title:	A Therapeutic Method for the Direct Reprogramming of Human Liver Cancer Cells with only Chemicals
Author:	Moriguchi, Hisashi; Mihara, Makoto; Sato, Chifumi; Zhang, Yue Note: Order does not necessarily reflect citation order of authors.
Citation:	Moriguchi, Hisashi, Yue Zhang, Makoto Mihara, and Chifumi Sato. 2012. A therapeutic method for the direct reprogramming of human liver cancer cells with only chemicals. Scientific Reports 2: 280.
Full Text & Related Files:	3282982.pdf (253.2Kb; PDF)
Abstract:	Various methods for the direct reprogramming of human somatic cells have been developed. However, a therapeutic method to reprogram and eliminate human solid tumor cells has not been developed. Here we show a novel therapeutic method to reprogram and eliminate human solid tumor cells with chemicals. This therapeutic method may be applicable to various human solid tumor cells that express aldo-keto reductase family 1 member B10 (AKR1B10) and retinoid X receptors (RXRs).
Published Version:	doi:10.1038/srep00280
Other Sources:	http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282982/pdf/
Terms of Use:	This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page:	http://nrs.harvard.edu/urn-3:HUL.InstRepos:8623556