A Therapeutic Method for the Direct Reprogramming of Human Liver Cancer Cells with only Chemicals

A Therapeutic Method for the Direct Reprogramming of Human Liver Cancer Cells with only Chemicals

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A Therapeutic Method for the Direct Reprogramming of Human Liver Cancer Cells with only Chemicals

dc.contributor.author	Moriguchi, Hisashi
dc.contributor.author	Mihara, Makoto
dc.contributor.author	Sato, Chifumi
dc.contributor.author	Zhang, Yue
dc.date.accessioned	2012-04-26T17:35:29Z
dc.date.issued	2012
dc.identifier.citation	Moriguchi, Hisashi, Yue Zhang, Makoto Mihara, and Chifumi Sato. 2012. A therapeutic method for the direct reprogramming of human liver cancer cells with only chemicals. Scientific Reports 2: 280.	en_US
dc.identifier.issn	2045-2322	en_US
dc.identifier.uri	http://nrs.harvard.edu/urn-3:HUL.InstRepos:8623556
dc.description.abstract	Various methods for the direct reprogramming of human somatic cells have been developed. However, a therapeutic method to reprogram and eliminate human solid tumor cells has not been developed. Here we show a novel therapeutic method to reprogram and eliminate human solid tumor cells with chemicals. This therapeutic method may be applicable to various human solid tumor cells that express aldo-keto reductase family 1 member B10 (AKR1B10) and retinoid X receptors (RXRs).	en_US
dc.language.iso	en_US	en_US
dc.publisher	Nature Publishing Group	en_US
dc.relation.isversionof	doi:10.1038/srep00280	en_US
dc.relation.hasversion	http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282982/pdf/	en_US
dash.license	LAA
dc.title	A Therapeutic Method for the Direct Reprogramming of Human Liver Cancer Cells with only Chemicals	en_US
dc.type	Journal Article	en_US
dc.description.version	Version of Record	en_US
dc.relation.journal	Scientific Reports	en_US
dash.depositing.author	Zhang, Yue
dc.date.available	2012-04-26T17:35:29Z