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dc.contributor.author	Gibbs, Karine Alexine
dc.contributor.author	Wenren, Larissa Man-Yin
dc.contributor.author	Greenberg, E. Peter
dc.date.accessioned	2012-05-06T19:43:38Z
dc.date.issued	2011
dc.identifier.citation	Gibbs, Karine Alexine, Larissa Man-Yin Wenren, and E. Peter Greenberg. 2011. Identity gene expression in Proteus mirabilis. Journal of Bacteriology 193(13): 3286-3292.	en_US
dc.identifier.issn	0021-9193	en_US
dc.identifier.issn	1098-5530	en_US
dc.identifier.uri	http://nrs.harvard.edu/urn-3:HUL.InstRepos:8667396
dc.description.abstract	Swarming colonies of independent Proteus mirabilis isolates recognize each other as foreign and do not merge together, whereas apposing swarms of clonal isolates merge with each other. Swarms of mutants with deletions in the ids gene cluster do not merge with their parent. Thus, ids genes are involved in the ability of P. mirabilis to distinguish self from nonself. Here we have characterized expression of the ids genes. We show that idsABCDEF genes are transcribed as an operon, and we define the promoter region upstream of idsA by deletion analysis. Expression of the ids operon increased in late logarithmic and early stationary phases and appeared to be bistable. Approaching swarms of nonself populations led to increased ids expression and increased the abundance of ids-expressing cells in the bimodal population. This information on ids gene expression provides a foundation for further understanding the molecular details of self-nonself discrimination in P. mirabilis.	en_US
dc.description.sponsorship	Molecular and Cellular Biology	en_US
dc.language.iso	en_US	en_US
dc.publisher	American Society for Microbiology	en_US
dc.relation.isversionof	doi:10.1128/​JB.01167-10	en_US
dc.relation.hasversion	http://www.ncbi.nlm.nih.gov/pubmed/21551301	en_US
dash.license	OAP
dc.title	Identity Gene Expression in Proteus Mirabilis	en_US
dc.type	Journal Article	en_US
dc.description.version	Author's Original	en_US
dc.relation.journal	Journal of Bacteriology	en_US
dash.depositing.author	Gibbs, Karine Alexine
dc.date.available	2012-05-06T19:43:38Z

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  Peer reviewed scholarly articles from the Faculty of Arts and Sciences of Harvard University

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