The Rise and Fall of Estrogen Therapy: The History of HRT

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The Rise and Fall of Estrogen Therapy: The History of HRT

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Title: The Rise and Fall of Estrogen Therapy: The History of HRT
Author: Rothenberg, Carla J.
Citation: The Rise and Fall of Estrogen Therapy: The History of HRT (2005 Third Year Paper)
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Abstract: This paper explores the history of hormone replacement therapy (“HRTâ€). It focuses on the development and marketing of HRT drugs, the regulation of HRT by the Food and Drug Administration (“FDAâ€), and the effect medical studies have had on the development, marketing, and regulation of HRT over the years. First, a discussion of the difficulty of defining menopause is explored. Second, the early history, treatments, and attitudes towards menopause are described. Next, the discovery, manufacture, and FDA approval of estrogen are detailed. The subsequent section examines how the pharmaceutical industry created a perception of menopause as a disease in all midlife women. Then, the cost-benefit analysis of HRT is explored through medical studies’ connection of HRT to various diseases. Finally, the aftermath of the landmark Women’s Health Initiative study is discussed, followed by a few concluding thoughts on what we can learn from the history of HRT.
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:8889430

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