The Historical Development of Animal Toxicity Testing

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The Historical Development of Animal Toxicity Testing

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dc.contributor.advisor Hutt, Peter Barton en_US
dc.contributor.author Gertler, N. en_US
dc.date.accessioned 2012-06-15T20:17:49Z
dc.date.issued 1997 en_US
dc.identifier.citation The Historical Development of Animal Toxicity Testing (1997 Third Year Paper) en
dc.identifier.uri http://nrs.harvard.edu/urn-3:HUL.InstRepos:8889439
dc.description.abstract This paper traces the historical development of animal toxicity testing, from its ancient origins through the period of standardization following World War II. It explores the roots of toxicity testing in physiology and experimental medicine, drug development, and the detection and identification of poisons. The discussion then turns to the shift in focus from acute to chronic toxicity which occurred around the turn of the century. The controversy over the potential toxicity of preservatives and pesticide residues illustrates the evolution of toxicity testing in the early to middle part of the twentieth century, as well as the influence of political and economic factors on its development. The paper concludes with the emergence of standardized protocols for toxicity testing during and immediately following the Second World war. en
dc.language.iso en_US en
dash.license LAA en_US
dc.subject Food and Drug Law en
dc.subject animal en
dc.subject toxicity en
dc.subject chemical en
dc.subject testing en
dc.title The Historical Development of Animal Toxicity Testing en
dc.type Paper (for course/seminar/workshop) en_US
dc.date.available 2012-06-15T20:17:49Z

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