Automating Microfluidics: Reconfigurable Virtual Channels for Cell and Droplet Transport

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Automating Microfluidics: Reconfigurable Virtual Channels for Cell and Droplet Transport

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Title: Automating Microfluidics: Reconfigurable Virtual Channels for Cell and Droplet Transport
Author: Floryan, Caspar Jerzy; Nemiroski, Alex; Westervelt, Robert M.

Note: Order does not necessarily reflect citation order of authors.

Citation: Floryan, Casper, Alex Nemiroski, and Robert M. Westervelt. 2012. Automating microfluidics: reconfigurable virtual channels for cell and droplet transport. School of Engineering and Applied Sciences, Harvard University.
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Abstract: The emerging field of digital microfluidics promises to solve many shortcomings of traditional continuous-flow fluidics. This technology has a few incarnations, including EWOD (eletrowetting on dielectric) and DEP (dielectrophoresis) chips. Both consist of large arrays of electrical pixels which move droplets and cells. They actuate fluids actively, have error feedback, are programmable, perform operations in parallel, and do not rely on external pumps. For these reasons we foresee the increased use of digital microfluidics in the near future. We also foresee a gradual shift away from purpose-built microfluidic devices, towards multi-purpose platforms with specific applications encoded in software. To this extent we present here a new paradigm of encoding and automating microfluidic operations using video files. We use this technology to create several configurations of virtual microfluidic channels and to play film clips using living cells on a DEP chip.
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:9273167

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  • FAS Scholarly Articles [7219]
    Peer reviewed scholarly articles from the Faculty of Arts and Sciences of Harvard University
 
 

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